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Soy-based natural S-equol supplements improve crow's feet skin wrinkles in menopausal women
Date:9/21/2011

WASHINGTON, DC (Sept. 21, 2011) A soy germ-based nutritional supplement containing Natural S-equol significantly improved the appearance of crow's feet skin wrinkles of the outer corner of the eyes in Japanese menopausal women, suggesting that supplements containing Natural S-equol have potential to slow skin aging, according to data from a controlled pilot study simultaneously published online in the peer-review journal Menopause and presented in a poster session at the North American Menopause Society (NAMS) annual meeting.

"While earlier studies have documented the beneficial effects of the Natural S-equol supplement on menopausal symptoms in postmenopausal women, this is the first study to examine its effects on menopausal skin, which were quite remarkable," said Belinda H. Jenks, Ph.D., Director of Scientific Affairs & Nutrition Education at Pharmavite LLC., and coauthor of the NAMS poster. "However, other larger studies using a longer treatment period and in menopausal women of different ethnicities are warranted to confirm and further characterize the effects of the Natural S-equol supplement on skin aging."

S-equol [7-hydroxy-3-(4'-hydroxyphenyl)-chroman] is a compound resulting -- when certain bacteria are present in the digestive tract -- from the natural metabolism, or conversion, of daidzein, an isoflavone found in whole soybeans. Not everyone can produce S-equol after soy consumption, as the production depends on the types of bacteria present in the large intestine and may be influenced by the amount of soy consumed. About 50 percent of Asians and 20 to 30 percent of North Americans and Europeans, who in general consume less soy than Asians, have the ability to produce high levels of S-equol naturally. Preliminary evidence from observational studies suggests that among Japanese women, those who produce S-equol naturally may have fewer menopausal symptoms. Controlled clinical trials have documented that a supplemen
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Contact: Stephen McCauley
smccauley@porternovelli.com
202-973-3615
Porter Novelli
Source:Eurekalert

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