Navigation Links
Soy May Reduce Breast Cancer Recurrence: Study

By Kathleen Doheny
HealthDay Reporter

MONDAY, Oct. 18 (HealthDay News) -- For women past menopause who have had breast cancer, a higher intake of soy may help reduce the risk of the disease's recurrence, a new study of Chinese women suggests.

The same link was not found in premenopausal women with breast cancer, whatever their soy intake, the study authors said.

The study, while called intriguing by U.S. experts, was not large and included only women with breast cancer receiving care in China. It's not known if the results would apply to other groups of women, said Marji McCullough, a spokeswoman for the American Cancer Society.

"Chinese women may have been likely to have a lifelong high consumption of soy," she said. "We don't know whether starting on a diet high in soy after a breast cancer diagnosis would have the same effect as eating a lifelong diet high in soy."

For the study, Dr. Qingyuan Zhang of the Cancer Hospital of Harbin Medical University in Harbin, China, evaluated 524 women who had undergone breast cancer surgery between August 2002 and July 2003. They were receiving endocrine therapy such as anastrozole (Arimidex) or tamoxifen to reduce cancer recurrence risk.

The researchers measured the women's dietary intake of soy isoflavones at the start of the study, and then followed them for about five years to see if breast cancer recurred.

For the premenopausal women, soy had no apparent effect on the risk of subsequent breast cancer.

But postmenopausal women with the highest intake of soy -- more than 42.3 milligrams of soy isoflavones a day -- had a 33 percent reduced risk of cancer recurrence. For patients receiving anastrozole and whose breast cancer was estrogen receptor-positive and progesterone receptor-positive, the risk reduction link was even stronger.

The study findings were published Oct. 18 in CMAJ (the Canadian Medical Association Journal).

A serving of soy milk has about 30 or 40 milligrams of isoflavones.

But Zhang cautioned that larger studies with women from many medical centers are needed before scientists can say that soy may help reduce the risk of breast cancer's return.

McCullough agreed. "It's still possible that other lifestyle differences in women in China who were eating less soy" might explain their higher likelihood of getting breast cancer again, she said.

There have been concerns about the effect of soy consumption on women with estrogen receptor-positive and progesterone receptor-positive breast cancer because soy isoflavones are similar to estrogen in chemical structure, and because tumor growth is dependent on estrogen, the study authors said in a news release.

Dr. Joanne Mortimer, director of the women's cancers programs at the City of Hope Comprehensive Cancer Center in Duarte, Calif., said some doctors tell women to avoid soy, concerned that too much might be hazardous. "I think this is yet another study that confirms that soy products do not cause an increased risk of breast cancer or even recurrence," she said.

But, it's not a reason to go overboard on soy, Mortimer said. "I wouldn't tell people they should eat a lot of soy," she said. Rather, "they should eat a healthy diet and if they eat soy, this study suggests there is not harm in it."

According to current American Cancer Society guidelines, which are under review, up to three servings a day of soy foods is considered safe, McCullough said. But women are advised to avoid the high soy dose found in more concentrated sources such as soy powders and isoflavone supplements, she said.

More information

To learn more about soy, visit the American Cancer Society.

SOURCES: Joanne Mortimer, M.D., director, women's cancers program, City of Hope Comprehensive Cancer Center, Duarte, Calif.; Marji McCullough Sc.D., R.D., strategic director, nutritional epidemiology, American Cancer Society, Atlanta; Oct. 18, 2010, CMAJ (Canadian Medical Association Journal)

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Vigorous exercise reduces breast cancer risk in African-American women
2. Adjunctive rufinamide reduces refractory partial-onset seizures
3. Dog ownership is associated with reduced eczema in children with dog allergies
4. After traumatic event, early intervention reduces odds of PTSD in children by 73 percent
5. Self-Touch May Reduce Pain, Study Finds
6. Nonstick coating of a protein found in semen reduces HIV infection
7. FDA Approves 1st Oral Drug to Reduce MS Relapses
8. Better marker for breast cancer may reduce need for second surgeries
9. Low-Dose Aspirin May Reduce Colon Cancer Risk
10. Successful periodontal therapy may reduce the risk of preterm birth, according to Penn dental study
11. Stopping smoking cessation treatments too soon may reduce odds of success for 45 percent of smokers
Post Your Comments:
Related Image:
Soy May Reduce Breast Cancer Recurrence: Study
(Date:11/27/2015)... , ... November 27, 2015 , ... A team of ... ways to treat it. Surviving Mesothelioma has just posted the findings on the website. ... Hospital Zurich analyzed the cases of 136 mesothelioma patients who were treated with chemotherapy ...
(Date:11/27/2015)... ... 27, 2015 , ... ProSidebar: Fashion is a set of 30 ... ProSidebar: Fasion, video editors can easily add an informative sidebar to any FCPX production. ... Utilize presets featuring self-animating drop zones, lines, bars, and text with the ease of ...
(Date:11/27/2015)... ... 27, 2015 , ... The moment you stop improving is ... fulfilling the needs of advisers and clients but going above and beyond to ... customer service. However, there's always room for improvement, which is why the entire ...
(Date:11/27/2015)... ... 2015 , ... Avid collector, Andrew Hawley from Vintage Rock Posters, announces his ... is one of Joplin's most famous and beautiful concert posters. The concert was held ... Ann Arbor. The According to Hawley, "It is hard to believe that Joplin's stardom ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... Travel Representative. As a franchise owner, Somu now offers travelers, value and care ... wedding packages, private cruise sales, as well as, cabin upgrades and special amenities ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 Research and ... "Asia Pacific Cardiac Pacemaker Market Outlook to 2019 - ... Drive the Demand " report to their offering. ... --> Boston scientific and others. ... global players including Medtronic, Biotronik, Boston ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 /PRNewswire/ ... the addition of the "2016 Future ... Drugs of Abuse Testing Market: Supplier Shares, ... report to their offering. --> ... of the "2016 Future Horizons and ...
(Date:11/26/2015)... , November 26, 2015 ... Juntendo universitetssjukhus ser potential att använda ... magnetresonansbilder (MR-bilder) för patienter med multipel ... ett forskningsavtal med SyntheticMR AB för att ... forskningsprojekt på sjukhuset. Med SyMRI kan man ...
Breaking Medicine Technology: