Navigation Links
Soy Chemicals May Lower Risk for Invasive Breast Cancer
Date:11/9/2010

By Amanda Gardner
HealthDay Reporter

TUESDAY, Nov. 9 (HealthDay News) -- The more isoflavone-containing soy products a young woman eats, the lower her odds for developing invasive breast cancers, according to research slated to be presented at a meeting of the American Association of Cancer Research in Philadelphia.

That was among the good news, but other research at the meeting found that hormone replacement therapy might raise women's odds for ovarian cancer.

The soy study looked specifically at isoflavones, organic compounds found in certain foods. These compounds contain antioxidants that are thought to be protective against breast cancer.

The study included 683 women with breast cancer and 611 women without the disease. It found that participants who consumed the most isoflavones had a 30 percent lower risk of developing an invasive tumor.

Examining the data more closely, researchers found that among premenopausal women, those who consumed the most isoflavones had a 30 percent decreased risk of early, stage I disease, a 70 percent decreased risk of having a tumor larger than 2 centimeters, and a 60 percent decreased risk of having stage 2 breast cancer. These connections were not seen among postmenopausal women, the researchers reported.

"Eating isoflavones seems to be associated mainly with breast cancer characteristics that are more treatable and less severe than other types," said study lead author Anne Weaver, a graduate student at the University at Buffalo and a research apprentice with Roswell Park Cancer Institute in Buffalo. She and the other researchers noted that the findings were not definitive and needed to be confirmed through further research.

"The biggest source of isoflavones are soy and soy products but they're also found in beans, cooked cereal, potato chips, coffee, cookies and cake," Weaver said. She cautioned that the overall intake of soy in the study was low -- in fact, 75 percent of participants reported never eating soy at all.

The hormone replacement therapy study aimed to see if different types of treatment (estrogen alone or estrogen-plus-progestin), the form of treatment (pill, patch, cream), or whether or not it was taken sequentially or continuously affected ovarian cancer risk.

During the 1990s, hormone replacement therapy was widely used by women to help control menopausal symptoms. However, data from the Women's Health Initiative study in 2002 suggested that the treatment raised risks for cardiovascular events and breast cancer, and rates of use fell precipitously.

In the new study, the authors examined data on almost 127,000 postmenopausal women in 10 European countries.

"Current use of hormone therapy was associated with a small but significant increased risk of ovarian cancer [29 percent compared to women who had never used hormone therapy] but there was no association for former use," said study lead author Konstantinos Tsilidis, a postdoctoral fellow in the Cancer Epidemiology Unit at the University of Oxford.

The longer a woman used the therapy, the higher the risk, although the only significant risk was seen among women who used hormone therapy for over five years. There seemed to be no difference in risk between type of therapy, by regimen or route of administration.

A third study presented at the conference found a heavy burden of side effects -- including hot flashes, sleep aberrations, hair loss and leg cramps -- in women taking aromatase inhibitor medications to treat their breast cancer.

"Aromatase inhibitors are associated with the new onset of a number of symptoms that occur much more frequently in women with breast cancer compared to women of the same age without cancer," said study lead author Lisa Gallicchio, an epidemiologist with the Prevention and Research Center at Mercy Medical Center in Baltimore. "These symptoms may affect quality of life and medication adherence which is crucial in reducing breast cancer recurrence and breast cancer-related mortality."

A previous study found that only 49 percent of patients took aromatase inhibitors "at the full duration at the optimal schedule," Gallicchio said. "That means 51 percent did not."

The current research was partially funded by pharmaceutical company Astra Zeneca.

A final study, this time by researchers at Yale University, found that exercising for at least 150 minutes a week reduces the odds of developing endometrial cancer by 34 percent.

The benefit was greater for slim women, who had a 73 percent reduced risk compared with heavy, sedentary women. But even overweight and obese women who exercised had a 52 percent reduced risk compared to their counterparts who didn't exercise.

More information

The U.S. National Cancer Institute has more on breast cancer.

SOURCE: Nov. 9, 2010 teleconference with Anne Weaver, graduate student, University at Buffalo and research apprentice, Roswell Park Cancer Institute; Konstantinos Tsilidis, Ph.D., postdoctoral fellow, Cancer Epidemiology Unit, University of Oxford; and Lisa Gallicchio, Ph.D., epidemiologist, The Prevention and Research Center, Mercy Medical Center, Baltimore; study abstracts.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Workplace Chemicals May Boost Breast Cancer Risk
2. Exposure to 3 classes of common chemicals may affect female development
3. Chemicals in Beauty Products Tied to Early Puberty in Girls
4. Two New Phytochemicals with Anti-Inflammatory Activity Found in Noni Fruit
5. Selenium Helped Cells Reboot After Exposure to Cancer-Causing Chemicals
6. Prenatal exposure to endocrine-disrupting chemicals linked to breast cancer
7. Endocrine-disrupting chemicals pose cancer risk
8. Natural Chemicals Act As Cancer Killers
9. Prenatal Exposure to Chemicals Linked to Breast Cancer Risk
10. Better animal-free test for chemicals that can cause contact dermatitis
11. More Cancer-Causing Chemicals in U.S. Cigarettes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Soy Chemicals May Lower Risk for Invasive Breast Cancer
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... Lori ... Greenberg Traurig, LLP’s Atlanta office, will speak at the American Conference Institute’s 21st ... Greenberg Traurig is also a Lead Sponsor of the conference. , Cohen, who chairs ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... Advanced Inc., ... it has appointed Jason Bice, CPA, MBA to serve as Advanced Inc.’s Chief Financial ... Advanced, Inc. , Jason brings extensive financial and operational leadership experience to Advanced ...
(Date:12/2/2016)... PITTSBURGH, PA (PRWEB) , ... December 02, 2016 , ... ... or struggling through rehabilitation of an injury, patients must find the one that works ... for his pain, he created a machine that worked and decided to share it ...
(Date:12/2/2016)... Delaware (PRWEB) , ... December 02, 2016 , ... ... released a new version of its SaaS LIMS, CloudLIMS Lite. CloudLIMS Lite helps ... sample entry through labeling, storing, shipping and disposal. The new version is a ...
(Date:12/2/2016)... Texas (PRWEB) , ... December 02, 2016 , ... Yisrayl ... that delves into how this current generation fits into Bible Prophecy. Yisrayl says this ... various facts pointing to this conclusion, showing how the details line up exactly with ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 2, 2016 Quantum Radiology,s Mobile Breast Center ... interpretation directly to women at the workplace, thereby maximizing ... as Delta Air Lines and SunTrust Bank, and community ... component of wellness initiatives. "I think it,s ... enables them to have a mammogram without taking a ...
(Date:12/2/2016)... CORDOBA, Spain , Dec. 2, 2016 ... additional natural sources apart from those derived from C. ... Córdoba, the Universita` di Napoli Federico II , ... have created the first comprehensive, critical, integrated and unified ... The article focuses on the remarkable chemical ...
(Date:12/2/2016)... , Dec. 2, 2016  The Addiction ... the Academy of Managed Care Pharmacy (AMCP), has ... can better address the opioid addiction crisis, including ... Therapies (MAT). ATAG,s newly released paper, ... Access to Naloxone," addresses many issues around gaps ...
Breaking Medicine Technology: