Navigation Links
Southampton scientists begin patient trials of new leukemia cancer vaccine
Date:1/31/2011

myeloid leukaemia."

Dr Katy Rezvani, clinical senior lecturer at Imperial College London and consultant haematologist at Imperial College Healthcare, says: "At Hammersmith Hospital we have been using targeted leukaemia drug therapies, like tyrosine kinase inhibitors, for over 10 years. While these drugs are the first line therapy for chronic myeloid leukaemia patients, they can rarely 'cure' the condition. This new vaccine has the potential to improve the outcome of leukaemia treatments and could serve as a method of managing solid tumours."

Professor Freda Stevenson, an immunologist at the University of Southampton who is also working on the study, adds: "I'm very pleased with the results from the laboratory research, and am optimistic the vaccine will be successful in making a real difference to patients with myeloid leukaemia."

In the study, each participant will receive six doses of DNA vaccine over a six month period, with further booster vaccinations if successful. The vaccine will be administered in a groundbreaking new way, using electroporation, in which controlled, rapid electrical pulses create permeability in cell membranes and enable increased uptake of biological material after its injection into muscle or skin tissue. The electroporation system was developed by the US pharmaceutical company Inovio.

Inovio's CEO Dr J Joseph Kim, says: "This study expands Inovio's long-standing relationship with the University of Southampton into an important disease area. We are proud that Inovio will make a significant contribution to this Phase II trial for these cancers with clear unmet medical needs."

The DNA vaccine was developed at the University with funding from Leukaemia & Lymphoma Research and Cancer Research UK.

Dr David Grant, Scientific Director of Leukaemia & Lymphoma Research, adds: "We are delighted to see this trial in leukaemia go ahead. It is an important step for us to see the laboratory wor
'/>"/>

Contact: Sophie Docker
S.Docker@soton.ac.uk
44-238-059-8933
University of Southampton
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Southampton scientists begin Phase II patient trial for new asthma treatment
2. Southampton to conduct UKs first cochlear implant operation to give sound in both ears
3. Scientists Pinpoint Area of Brain That Fears Losing Money
4. Scientists Discover How HIV Is Transmitted Between Men
5. Prevention Is Key Research Goal for Premature Babies, Scientists Say
6. Scientists Discover Molecular Pathway for Organ Tissue Regeneration and Repair
7. Scientists find donut-shaped structure of enzyme involved in energy metabolism
8. Neuroscientists reveal new links that regulate brain electrical activity
9. Two UCSF Scientists to Receive Prestigious Dementia Research Honor
10. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
11. Scientists Spot Genetic Fingerprints of Individual Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... ... ... sweetFrog Enterprises, LLC. is pleased to announce the opening of its newest location ... The premium frozen yogurt chain was listed as #22 on the Inc. 500 list ... New Albany, MS 38652, will have a grand opening event on July 4, 2015 ...
(Date:7/2/2015)... ... ... sweetFrog Enterprises, LLC. is pleased to announce the opening of its newest ... the Lone Star State. The premium frozen yogurt chain was listed as #22 on ... opened July 1 at Duke’s Travel Plaza, is located at:, 30176 Hwy 64, Suite ...
(Date:7/2/2015)... ... July 02, 2015 , ... The American Association of ... the Stop Overdose Stat (S.O.S.) Act of 2015 on June 23, 2015. Together ... seeks to decrease drug overdose – especially of heroin and opioid medication – ...
(Date:7/2/2015)... Lincoln, RI (PRWEB) , ... July 02, 2015 , ... ... keep safety in mind. That’s why Amica Insurance is sharing some tips ... Safety Commission (CPSC), approximately 230 people go to the emergency room daily with fireworks-related ...
(Date:7/2/2015)... , ... July 02, 2015 , ... In 2012, Patrick Achebe realized that the gift ... alone. He sat down to write his first poem, and three years later he was ... was special and worth sharing with the world. "I have always believed that the best ...
Breaking Medicine News(10 mins):Health News:sweetfrog Opens First Location in Mississippi 2Health News:sweetFrog Expands Texas Footprint with Location in Canton 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 2Health News:AAPCC Supports the Stop Overdose Stat Act of 2015 3Health News:6 Fireworks Safety Tips from Amica Insurance 2Health News:Patrick Achebe Releases Debut Book, Whispering Waves: Poems for Everyday Grace 2
... PRESSURE DOES NOT PREDICT EFFECT ON HEART IN CHILDREN // ... lead to a potentially dangerous enlargement of the heart, according ... Hopkins Children's Center and the Children's Hospital at Montefiore in ... children, at least, that the higher the blood pressure the ...
... with Actonel are more likely to sustain when ... in the peer-reviewed journal Osteoporosis International after collecting ... ,The study of 33,000 postmenopausal women showed that ... most popular osteoporosis treatments, patients taking Actonel? (risedronate ...
... Support to Primary Education (commonly known as Mid-Day Meal ... the world //covering nearly 12 crore children in more ... Innovative Education (AIE) centers. ,The scheme provides ... and 12 gms of protein. The Scheme has been ...
... conducted a survey on “Man Flu”. "Man flu," is that mysterious ... barely seem to affect their female counterparts, " according to Nuts, ... per cent of men had Flu, that forced them to stay ... cent of women said the same. The survey also revealed that ...
... exercise works well for weight loss, but dieters end up ... want to lose weight in their 50s and 60s, to ... calories. ,Both, those who dieted and those who ... from the study on ‘whether a calorie-restriction diet can extend ...
... the stigma of the disease. // ,According to official ... to 1.56 percent in 2005, from 14.7 percent in 2001. ... cured are called, have been roped in since leprosy is on ... Ranchi has gone up to 1.60 percent between April and August, ...
Cached Medicine News:Health News:Children and Chronic Kidney Disease 2Health News:Children and Chronic Kidney Disease 3Health News:Actonel Treats Hip Fractures In A Better Way Than Alendronate 2Health News:Mid-Day Meal Scheme Catches on in India 2Health News:Which Is Better For Losing Weight? - Diet Or Exercise 2
(Date:7/2/2015)... 25, 2015 Research and Markets( http://www.researchandmarkets.com/research/nlfg34/cancer ... by Technology, Imaging and by Application - Forecast to 2020" ... is expected to reach $13.1 Billion in 2020 from an estimated ... The market is dominated by North America ... , and Rest of the World (RoW). The cancer diagnostics ...
(Date:7/2/2015)... Mass. , July 2, 2015   ... and European retinal specialists identify less frequent dosing ... edema (DME), due to the burden on both ... anti-vascular endothelial growth factor (VEGF) injections, which are ... Allergan/Molecular Partners, abicipar pegol, which is in development ...
(Date:7/2/2015)... 2015 BGI gab heute bekannt, ... vom American College of Pathologists (CAP) akkreditiert ... erste klinische Next-Generation-Sequencing Labor, das in ... und somit die höchsten Standards an klinischer ... FDA - 21 CFR Part 11 konformen ...
Breaking Medicine Technology:Global Cancer Diagnostics Market Report 2015 - Technology, Imaging and by Applications Forecasts to 2020 for the $13 Billion Industry 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 3BGI erhält Akkreditierung vom College of American Pathologists (CAP) 2
... MOUNTAIN VIEW, Calif., April 28, 2011 IRIDEX Corporation (NASDAQ: ... quarter 2011 financial results after the market closes on ... the Company will host a conference call with the investment community ... Thursday, May 5, 2011 to discuss the results ...
... April 28, 2011 PharmaNet Development Group, Inc., a ... generic drug and medical device companies, announced today that ... President, Corporate Quality Assurance. "We are ... Newman, MD, President, PharmaNet Development Group. "Valerie brings deep ...
Cached Medicine Technology:
The HEP-3, with a transfer area of 35cmW x 45cmL, is designed specifically for the transfer of nucleic acids from sequencing gels to nylon membranes....
... electrophoretic transfer cell and PowerPac 200 ... Transfers. Minimal Buffer Requirements. ... Reliable Transfers. Single-Step Locking System ... to Transfer Multiple Gels. New ...
PosiBlot 30-30 Sponges...
Ice block will provide sufficient cooling for most normal blotting applications. Sealed block is held submerged in transfer buffer. Ice block will not spill during refreezing....
Medicine Products: