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South Asian patients require 3 times as much repeat angioplasty as white Europeans
Date:11/21/2011

dure was carried out was similar in both ethnic groups.

  • A total of 111 patients required repeat revascularisation. Of these, 94 had a repeat PCI and 17 underwent coronary artery bypass grafting. South Asian patients were almost three times as likely to be readmitted for PCI (15.7% v 5.5%) or coronary artery bypass grafting (2.7% v 1.0%).

  • Following the initial procedure, South Asian patients also required more PCI for treatment of non-index lesions (24.2% v 8.9%). After controlling for baseline clinical and procedural characteristics, South Asian ethnicity was a significant independent predictor of target lesion revascularisation, with levels approximately three times higher (18.4% v 6.6%).

  • The patients were followed up for a median of 54 months. During this period 12% of the patients died, but there was no statistically significant difference in the two groups when it came to all-cause death.

  • Social deprivation was three times higher among South Asian patients (10.2 v 3.3 points) as measured by the Carstairs index, which is based on key census indicators. The hospital's catchment area includes areas with unemployment rates of twice the national average and the second lowest average earnings in England and Wales.

  • Each one point increase in the Carstairs social deprivation score was matched by a 5% increase in the risk of long-term, all-cause death.

  • Further analysis (Cox regression) showed that age, history of heart attacks, social deprivation score and creatinine levels before treatment were independent predictors of long-term, all-cause death in the whole study group.

    "South Asians develop symptomatic coronary artery disease at an earlier age and also have a higher prevalence than White Europeans" concludes Dr Varma. "PCI can be used for symptomatic relief in stable angina and to improve prognosis in acute coronary syndrome.

    "Despite needing more urgent hospi
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    • Contact: Annette Whibley
    annette.wizard@gmail.com
    Wiley-Blackwell
    Source:Eurekalert

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