Navigation Links
Songbird brain synapses and glial cells capable of synthesizing estrogen
Date:1/3/2012

Colin Saldanha, a biology professor at American University in Washington, D.C., has always been intrigued by the hormone estrogen. Specifically, how the hormone that does so much (for example, it promotes sexual behavior in women but can also increase susceptibility to seizures) does not cause major cross circuit meltdowns.

"In the extreme case, once every 28 days, women should be having seizuresand when they do, it's a condition called Catamenial Epilepsybut that's obviously not the norm and there's the mystery," Saldanha said. "Somehow, the vertebrate body has figured out a way to produce and provide estrogen to precisely the right part of the body at precisely the right time."

To attempt to find out how the bodies of animals and humans can do this, Saldanha has been studying the brains of songbirdsspecifically, adult male zebra finches. Why adult male zebra finches? Male zebra finches sing, but the females do not. During the springmating season, when males court prospective mates with their songsparts of the male birds' brains nearly double in size only to shrink back to normal size in the fall when mating season has ended. Estrogen is behind the phenomenon.

Discovery Leads to a New Term

Previous research on hormone synthesis outlines three ways the body makes and delivers estrogen to different parts:

  • Endocrine signaling (estrogen produced in the ovaries and made available to the entire body through the bloodstream);
  • Paracrine signaling (estrogen made in the brain but stays local/ in the area where it was made);
  • And autocrine signaling (estrogen made in an individual cell for use in that cell).

Recently, Saldanha and colleagues from the University of MassachussettsAmherst and the University of CaliforniaLos Angeles, published research that introduced a fourth and new method of estrogen synthesis to the scientific community: synaptocrine signaling, or at the synapse.


'/>"/>
Contact: American University Communications
aumedia@american.edu
202-885-5950
American University
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Songbirds strategy for changing its tune could inform rehab efforts
2. Gadgets not related to teenagers brain pain
3. Dementia Rates Escalate as Brain Capacity Diminishes with Age
4. Researchers discover new way to kill pediatric brain tumors
5. Scientists Pinpoint Area of Brain That Fears Losing Money
6. Physical Changes in Brain Linked to Altered Spirituality
7. Pro Athletes Brains React at Olympic Speed
8. Neuroscientists reveal new links that regulate brain electrical activity
9. Brain Scan Shows What Beauty is Worth
10. Study supports alternative anti-seizure medication following acute brain injury
11. Exercise helps protect brain of multiple sclerosis patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... The ALS Association, along with its Western Pennsylvania ... Health Network as a Certified Treatment Center of ... (AGH), is the only ALS treatment program in western ... highest levels of established national standards of care in ... to as Lou Gehrig’s Disease. , Allegheny Health Network’ ...
(Date:8/22/2014)... Human induced pluripotent stem cells (hiPSCs) ... because they can be coaxed to turn into specific ... anticipated. They sometimes mutate, develop into tumors or produce ... recently published in STEM CELLS Translational Medicine, researchers appear ... removing the material used to reprogram the stem cell ...
(Date:8/22/2014)... News) -- The air in American cities is getting ... Thursday. Significant progress has been made in reducing ... decades, the agency said in a news release. ... reduction in mercury from human sources such as coal-fired ... 84 percent fall in lead, which harms brain development ...
(Date:8/22/2014)... Dennis Thompson HealthDay ... -- The two American health-care workers infected with the ... West Africa have been released from the Atlanta hospital ... officials said Thursday. Dr. Kent Brantly, 33, was ... Writebol left the hospital Tuesday. Her family said the ...
(Date:8/22/2014)... Ticket Down is a reliable source for cheap ... Rentschler Field. There has never been a better time to be ... After the strong showing at the 2014 World Cup in Brazil, ... featured in large stadiums around the country. Since the World Cup ... some of the best club teams in the sport played on ...
Breaking Medicine News(10 mins):Health News:Allegheny Health Network ALS Program Named Certified Treatment Center of Excellence 2Health News:Allegheny Health Network ALS Program Named Certified Treatment Center of Excellence 3Health News:Removing Programming Material After Inducing Stem Cells Could Improve Their Regeneration Ability 2Health News:Air in U.S. Cities Getting Cleaner, EPA Says 2Health News:Both U.S. Health-Care Workers Infected With Ebola Released From Hospital 2Health News:Both U.S. Health-Care Workers Infected With Ebola Released From Hospital 3Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 2Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 3
... cold and flu and ,allergy products , ... Los ... selected GolinHarris as agency of record to lead its public relations ... charged with ongoing strategic counsel, product messaging, traditional media outreach and ...
... peoples , , THURSDAY, Jan. 8 (HealthDay News) -- Genetic evidence ... is now Siberia at about the same time to become ... , Approximately 15,000 to 17,000 years ago, one group ... which once connected northeast Siberia to Alaska, and moved down ...
... is much more likely to be deadly for women and ... account for only part of the differences for such patients ... published in the Jan. 1 issue of the journal ... patients: If age, tumor type, and stage of the disease ...
... support local programs as part of a nationwide Special ... Olympics Minnesota recently received $20,000 in funding to support ... national program. Project UNIFY is an initiative to activate ... to promote school communities where all young people are ...
... from the University of Granada and the University of ... triterpenoid compound isolated from olive-skin pomace, results in a ... in colon-cancer cells. Maslinic acid is a novel natural ... programmed death in human HT29 colon-cancer cells via the ...
... nasal spray vaccine to provide complete protection against a major ... Nature journal Gene Therapy . , Botulism is caused ... that cause paralysis and often death, as the muscles that ... cases each year, 65 percent are infant botulism (infants, intestines, ...
Cached Medicine News:Health News:Matrixx Initiatives Selects GolinHarris as Agency of Record for Zicam Brand 2Health News:Matrixx Initiatives Selects GolinHarris as Agency of Record for Zicam Brand 3Health News:First Americans Arrived on 2 Separate Paths 2Health News:Why Bladder Cancer Is Deadlier for Some 2Health News:Why Bladder Cancer Is Deadlier for Some 3Health News:Why Bladder Cancer Is Deadlier for Some 4Health News:Special Olympics Minnesota Launches Project UNIFY to Energize Youth 2Health News:Nose-spray vaccine against botulism effective in first tests 2Health News:Nose-spray vaccine against botulism effective in first tests 3Health News:Nose-spray vaccine against botulism effective in first tests 4
(Date:8/21/2014)... , Aug. 21, 2014  Zacks.com announces the list ... Zacks Equity Research analysts discuss the latest news and events ... the blog include the Hewlett-Packard (NYSE: HPQ - Free Report ... Bulkers, Inc. (NYSE: SB - Free Report ), GlaxoSmithKline ... International N.V. (NYSE: FI - Free Report ). ...
(Date:8/21/2014)... 21, 2014 InfinityQS International, Inc., the ... Intelligence , today announces Infusion Chicago, its 9 ... be held Oct. 9-10, 2014, at the Chicago ... showcase the necessity for implementing a quality system ... Intelligence to gain insight into production processes. Complimentary ...
(Date:8/21/2014)... , Aug. 21, 2014  The board of directors ... leading provider of clinical trial imaging solutions, today announced ... chief financial officer, effective immediately.  Mr. Groff has held ... 2013.  He joined VirtualScopics in January 2006 as an ... 2013. "When the board of VirtualScopics asked ...
Breaking Medicine Technology:The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 2The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 3The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 4The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 5The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 6The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 7The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 8The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 9The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 10The Zacks Analyst Blog Highlights: Hewlett-Packard, IBM, Safe Bulkers, GlaxoSmithKline and Frank's International 11InfinityQS to Host Manufacturing Intelligence Conference in Chicago 2VirtualScopics, Inc. Names James Groff Chief Financial Officer 2VirtualScopics, Inc. Names James Groff Chief Financial Officer 3VirtualScopics, Inc. Names James Groff Chief Financial Officer 4
... FRANCISCO, June 22, 2011 Autonomy Corporation plc ... infrastructure software for the enterprise, today announced that the ... Autonomy,s flagship Web Content Management (WCM) platform, has twice ... Site Monitor performance report. The Swiss Pharma Site Monitor ...
... FALL RIVER, Mass., June 21, 2011 Millstone ... introduced an advanced version of its online inventory ... refinement, Millstone launched a new online, password-protected system ... place orders, and manage distribution.  Benefits of the ...
Cached Medicine Technology:Autonomy Powers Award-Winning Website for Leading Swiss Pharmaceutical Company 2Autonomy Powers Award-Winning Website for Leading Swiss Pharmaceutical Company 3Autonomy Powers Award-Winning Website for Leading Swiss Pharmaceutical Company 4Millstone Medical Outsourcing Introduces Advanced Version of Online Inventory Management System 2
Hard protective shields for post-operative or post-injury use. Universal, or Left/Right specific. Packaged 12 per box....
... a broad selection of tip ... wide variety of ophthalmic procedures. ... packaged sterile, complete with a ... in the "off " position ...
... broad selection of tip styles for ... ophthalmic procedures. Each single use cautery ... safety cap to lock switch in ... in use, and carries a 3-4 ...
... provide a broad selection of tip ... variety of ophthalmic procedures. Each single ... with a safety cap to lock ... when not in use, and carries ...
Medicine Products: