Navigation Links
Some types of papilloma virus might prevent cervical cancer
Date:4/10/2013

Certain types of papilloma virus might actually prevent cervical cancer, according to a new study by researchers from The University of Manchester.

There are over 100 different types of human papilloma virus (HPV). Cervical cancer is known to be caused by infection with approximately 14 so-called "high-risk" types of this virus. Researchers from Manchester looked at the different types of HPV found in cervical smears and invasive cervical cancers from HIV positive and HIV negative women in Kenya. They found high numbers of a specific type of HPV (type 53) in normal cervical smears from HIV positive women, but this was rarely found in HIV negative women. This sub-type was also never found in cervical cancers from either HIV positive or negative women.

Dr Ian Hampson, a Senior Lecturer in Viral Oncology from The University of Manchester who lead the study, said: "It is well known that HIV increases the number of different types of HPV found in any one patient which implies that HIV opens the door for infection with multiple types of HPV. If only high-risk types are present these will undoubtedly accelerate progression to cancer whereas if other types (eg type 53) are also present they may actually compete with the high-risk types to inhibit progression to cervical cancer."

There are 270,000 deaths from cervical cancer globally each year with 85% of these occurring in countries with low resources. In Kenya it is the most common malignancy accounting for between 18 and 23 per cent of all diagnosed cases of cancer.

The study looked at women at samples taken from women in Kenya and results were analysed at The University of Manchester's Viral Oncology Laboratories based at the Saint Mary's Hospital. Completed by Dr Ian Hampson, Dr Lynne Hampson and Dr Innocent Orora Maranga the results have been published in The Open Virology Journal.

Dr Hampson said the study suggested one possible explanation for why, in spite of a large increase in the numbers of HPV infections in HIV positive African women, there was not a corresponding increase in numbers of cases of cervical cancer. This could also explain why another African study had actually shown the risk of developing one specific type of cervical cancer actually dropped in HIV-positive women, he said.

The researchers now plan to do more research in this area. "Our study was quite small and more research with larger sample numbers is now needed," Dr Hampson said. "We also need to work out exactly how one type of HPV might suppress the cancer causing properties of another. If it can be proved that HPV type 53 can inhibit the cancer-causing properties of other high-risk types of HPV, this could potentially form the basis of a simple biological therapy to prevent this disease. This could be extremely useful in low resource countries who cannot afford expensive HPV vaccines."


'/>"/>

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-172-58383
University of Manchester
Source:Eurekalert

Related medicine news :

1. FreelanceCoach.com Adds Two More Professional Types, Plans Release of New Chat Feature
2. More Genetic Insights Into 3 Types of Cancer
3. Avanquest Recommends MOD, MOV, and MP4 Types of Software
4. UNC-led study documents head and neck cancer molecular tumor subtypes
5. Negative stereotypes about boys hinder their academic achievement
6. Zane Benefits Publishes New Information on Types of Health Insurance Plans
7. Breast Milk Contains More Than 700 Bacteria Types: Study
8. Survival Equal in 2 Types of Abdominal Aneurysm Repair: Study
9. World Trade Center rescue, recovery workers have had increased incidence of certain types of cancer
10. Transport infrastructure determines spread of HIV subtypes in Africa
11. Ponatinib acts against the most resistant types of chronic myeloid leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2017)... , ... June 27, 2017 , ... Today, June 27th ... from PTSD. Yet less than 20% will receive adequate care due to lack of ... won't receive any care at all. And left untreated, veterans are at an increased ...
(Date:6/26/2017)... ... 2017 , ... Antoine Dental Center is now offering various types of dental implants ... as a support for prosthetic teeth, such as crowns, bridges, or dentures. An implant is ... sturdy, lasting new root for the tooth. , Several types of dental implants are ...
(Date:6/26/2017)... , ... June 26, 2017 , ... LARKR™ , ... health professionals in every state across the country to join its online treatment platform. ... way for therapists to reach a substantially greater number of people in need nationwide, ...
(Date:6/25/2017)... ... June 24, 2017 , ... Create a feel-good lyric music video in Final Cut Pro X ... the timeline and write in the lyrics to any song. ProLyric flies in the text ... of the text can be added modularly for optimal control. ProLyric makes editing any music ...
(Date:6/25/2017)... ... ... Health Month and the focus is on prostate cancer. Second only to skin cancer, ... most common cause of cancer related death today; lung cancer remains in the number one ... cancer during his lifetime. Those at highest risk are men who have a ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... 8, 2017  StatLab Medical Products ("StatLab" ... manufacturer of diagnostic supplies for the anatomic ... & Company LP ("Cressey & Company"), a ... growth-focused investment in the Company. Cressey & ... from selling shareholder, Prairie Capital, L.P., with ...
(Date:6/5/2017)... June 5, 2017 Kohll,s Pharmacy & Homecare is the ... the United States . The Raizer is a simple ... person up to an almost-standing position within a ... by one assistant and does not require any ... that a child can operate it, and lightweight ...
(Date:5/30/2017)... CHICAGO , May 30, 2017 Hill-Rom Holdings, ... th Annual Global Healthcare Conference on Tuesday, June 13, ... John Greisch , Hill-Rom,s president and chief executive officer, ... The live audio webcast can be accessed at ... after conclusion of the live event through September 13, 2017. ...
Breaking Medicine Technology: