Navigation Links
Some types of papilloma virus might prevent cervical cancer
Date:4/10/2013

Certain types of papilloma virus might actually prevent cervical cancer, according to a new study by researchers from The University of Manchester.

There are over 100 different types of human papilloma virus (HPV). Cervical cancer is known to be caused by infection with approximately 14 so-called "high-risk" types of this virus. Researchers from Manchester looked at the different types of HPV found in cervical smears and invasive cervical cancers from HIV positive and HIV negative women in Kenya. They found high numbers of a specific type of HPV (type 53) in normal cervical smears from HIV positive women, but this was rarely found in HIV negative women. This sub-type was also never found in cervical cancers from either HIV positive or negative women.

Dr Ian Hampson, a Senior Lecturer in Viral Oncology from The University of Manchester who lead the study, said: "It is well known that HIV increases the number of different types of HPV found in any one patient which implies that HIV opens the door for infection with multiple types of HPV. If only high-risk types are present these will undoubtedly accelerate progression to cancer whereas if other types (eg type 53) are also present they may actually compete with the high-risk types to inhibit progression to cervical cancer."

There are 270,000 deaths from cervical cancer globally each year with 85% of these occurring in countries with low resources. In Kenya it is the most common malignancy accounting for between 18 and 23 per cent of all diagnosed cases of cancer.

The study looked at women at samples taken from women in Kenya and results were analysed at The University of Manchester's Viral Oncology Laboratories based at the Saint Mary's Hospital. Completed by Dr Ian Hampson, Dr Lynne Hampson and Dr Innocent Orora Maranga the results have been published in The Open Virology Journal.

Dr Hampson said the study suggested one possible explanation for why, in spite of a large increase in the numbers of HPV infections in HIV positive African women, there was not a corresponding increase in numbers of cases of cervical cancer. This could also explain why another African study had actually shown the risk of developing one specific type of cervical cancer actually dropped in HIV-positive women, he said.

The researchers now plan to do more research in this area. "Our study was quite small and more research with larger sample numbers is now needed," Dr Hampson said. "We also need to work out exactly how one type of HPV might suppress the cancer causing properties of another. If it can be proved that HPV type 53 can inhibit the cancer-causing properties of other high-risk types of HPV, this could potentially form the basis of a simple biological therapy to prevent this disease. This could be extremely useful in low resource countries who cannot afford expensive HPV vaccines."


'/>"/>

Contact: Alison Barbuti
alison.barbuti@manchester.ac.uk
44-016-172-58383
University of Manchester
Source:Eurekalert

Related medicine news :

1. FreelanceCoach.com Adds Two More Professional Types, Plans Release of New Chat Feature
2. More Genetic Insights Into 3 Types of Cancer
3. Avanquest Recommends MOD, MOV, and MP4 Types of Software
4. UNC-led study documents head and neck cancer molecular tumor subtypes
5. Negative stereotypes about boys hinder their academic achievement
6. Zane Benefits Publishes New Information on Types of Health Insurance Plans
7. Breast Milk Contains More Than 700 Bacteria Types: Study
8. Survival Equal in 2 Types of Abdominal Aneurysm Repair: Study
9. World Trade Center rescue, recovery workers have had increased incidence of certain types of cancer
10. Transport infrastructure determines spread of HIV subtypes in Africa
11. Ponatinib acts against the most resistant types of chronic myeloid leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to ... app. The fitness app plans to fix the two major problems leading the fitness industry ... fits all type program , They don’t eliminate all the reasons people quit ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 26, 2016 Story ... operating models within the health care industry is causing ... efficiency , Deloitte offers a suite of solutions ... issues impacting efficient cost optimization: labor resource analysis, revenue ... services facilitate better outcomes and better economics ...
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: