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Some on Statins May Not Need Boost in 'Good' Cholesterol
Date:7/22/2010

risk of cardiovascular events by 25 to 50 percent, it has been speculated that low HDL cholesterol levels may account for a large component of the residual vascular risk that remains despite statin therapy."

In the cases of primary prevention patients treated with statins, this latest finding challenges that hypothesis, Fonarow said.

"The most evidence-based and effective approach to reduce the risk of heart attack and stroke is lowering LDL cholesterol with maximally tolerated doses of statin therapy, along with lifestyle modification, even in the setting of low HDL," he said.

More information

For more information on cholesterol, visit the American Heart Association.

SOURCES: Paul Ridker, M.D., M.P.H., Eugene Braunwald Professor of Medicine, Harvard Medical School, director, Center for Cardiovascular Disease Prevention, Brigham and Women's Hospital, Boston; Gregg C. Fonarow, M.D., professor, medicine, and director, Ahmanson-UCLA Cardiomyopathy Center, University of California, Los Angeles; July 22, 2010, The Lancet


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