Navigation Links
Some People With Alzheimer's Take Conflicting Drugs
Date:10/28/2011

FRIDAY, Oct. 28 (HealthDay News) -- Many Alzheimer's patients who take cholinesterase inhibitors to slow their brain disease also take drugs that counter the effects of those Alzheimer's medications, a new study says.

Clinical trials have shown that cholinesterase inhibitors such as Aricept (donepezil) have a modest impact on the functional and cognitive decline caused by Alzheimer's disease, noted the researchers at the Group Health Research Institute in Seattle.

"Cholinesterase inhibitors are today's primary therapy for slowing Alzheimer's disease," study leader Denise Boudreau said in an institute news release.

"Anticholinergic properties are often found in drugs commonly used to treat gastrointestinal disorders, allergies, urinary incontinence, depression and Parkinson's disease, and they can have negative effects on cognition and function in the elderly. There's concern that if someone is taking both types of drugs -- cholinesterase inhibitors and anticholinergic medications -- they will antagonize each other, and neither will work," she explained.

Common anticholinergic medications include Benadryl (diphenhydramine) and Ditropan (oxybutynin), which is prescribed for overactive bladders.

Boudreau and colleagues analyzed data from more than 5,600 patients aged 50 and older who had cholinesterase inhibitors prescribed to them for the first time between 2000 and 2007. Of those patients, 37 percent also took at least one anticholinergic drug and more than 11 percent took two or more anticholinergic drugs.

Among the patients who took both classes of drugs, dual use generally lasted three to four months, but one-quarter of the patients used both classes of drugs for more than a year.

The researchers also found that 23 percent of patients who received a new prescription for cholinesterase inhibitors were already using at least one anticholinergic drug, and 77 percent of those patients continued taking an anticholinergic drug after they began taking a cholinesterase inhibitor.

"It's reassuring that we did not observe an association between simultaneous use of the two types of drugs and increased risk of death or nursing home placement," Boudreau said in the release. "But concomitant use of these drugs is, at the very least, not optimal clinical practice."

The study was published online Oct. 22 in the Journal of the American Geriatrics Society.

Alzheimer's patients often have multiple health problems, which may help explain why doctors might prescribe conflicting medications for these patients, the researchers said.

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.

-- Robert Preidt

SOURCE: Group Health Research Institute, news release, Oct. 25, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Obese people regain weight after dieting due to hormones
2. Multiple malaria vaccine offers protection to people most at risk
3. Computer games help people with Parkinsons disease
4. People With Mental Health Issues More Likely to Be Uninsured
5. Researcher identifies autism employment resources, tips for people with autism spectrum disorders
6. We discount the pain of people we dont like
7. Older people are happier in Brazil and South Africa
8. Easily embarrassed? Study finds people will trust you more
9. First detection of pregnancy protein in older people destined for Alzheimers disease
10. People learn while they sleep, study suggests
11. Interactive mobile app from UCSF and QuantiaMD teaches people how to manage diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Some People With Alzheimer's Take Conflicting Drugs
(Date:10/13/2017)... ... October 13, 2017 , ... ... that offers insurance and financial preparation services, is providing an update on a ... organization. , Rock City Rescue is a locally recognized nonprofit that provides shelter ...
(Date:10/13/2017)... ... 13, 2017 , ... PurhealthRX , a leading Health and Nutrition Company, ... Purzorbâ„¢process to full spectrum CBD oil will revolutionize the rapidly growing CBD market by ... be easily incorporated into liquid products, while reducing costs to end users. , The ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... The Visiting ... Day Market. Featuring a collection of specialty vendors and unique items from across the ... and quality-focused health and wellness services offered by the VNA. The boutique will ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the ... today its plans to open a flagship location in Covington, LA at 401 N. ... To Go store next to Office Depot in the Holiday Square shopping center. Its ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance ... a medical-grade battery-powered display stand specifically designed for endoscopy environments. An ... technology into a clinical solution to support the improvement of patient ... Innovative Design ... Wireless Solution ...
(Date:10/4/2017)... the Centers for Disease Control and Prevention (CDC), influenza vaccination should ... helping communities across Massachusetts , Connecticut ... shots through the end of the month. *Some exclusions apply ... ... is by the end of October, according to the Centers for Disease ...
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
Breaking Medicine Technology: