Navigation Links
Some People With Alzheimer's Take Conflicting Drugs
Date:10/28/2011

FRIDAY, Oct. 28 (HealthDay News) -- Many Alzheimer's patients who take cholinesterase inhibitors to slow their brain disease also take drugs that counter the effects of those Alzheimer's medications, a new study says.

Clinical trials have shown that cholinesterase inhibitors such as Aricept (donepezil) have a modest impact on the functional and cognitive decline caused by Alzheimer's disease, noted the researchers at the Group Health Research Institute in Seattle.

"Cholinesterase inhibitors are today's primary therapy for slowing Alzheimer's disease," study leader Denise Boudreau said in an institute news release.

"Anticholinergic properties are often found in drugs commonly used to treat gastrointestinal disorders, allergies, urinary incontinence, depression and Parkinson's disease, and they can have negative effects on cognition and function in the elderly. There's concern that if someone is taking both types of drugs -- cholinesterase inhibitors and anticholinergic medications -- they will antagonize each other, and neither will work," she explained.

Common anticholinergic medications include Benadryl (diphenhydramine) and Ditropan (oxybutynin), which is prescribed for overactive bladders.

Boudreau and colleagues analyzed data from more than 5,600 patients aged 50 and older who had cholinesterase inhibitors prescribed to them for the first time between 2000 and 2007. Of those patients, 37 percent also took at least one anticholinergic drug and more than 11 percent took two or more anticholinergic drugs.

Among the patients who took both classes of drugs, dual use generally lasted three to four months, but one-quarter of the patients used both classes of drugs for more than a year.

The researchers also found that 23 percent of patients who received a new prescription for cholinesterase inhibitors were already using at least one anticholinergic drug, and 77 percent of those patients continued taking an anticholinergic drug after they began taking a cholinesterase inhibitor.

"It's reassuring that we did not observe an association between simultaneous use of the two types of drugs and increased risk of death or nursing home placement," Boudreau said in the release. "But concomitant use of these drugs is, at the very least, not optimal clinical practice."

The study was published online Oct. 22 in the Journal of the American Geriatrics Society.

Alzheimer's patients often have multiple health problems, which may help explain why doctors might prescribe conflicting medications for these patients, the researchers said.

More information

The U.S. National Institute on Aging has more about Alzheimer's medications.

-- Robert Preidt

SOURCE: Group Health Research Institute, news release, Oct. 25, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Obese people regain weight after dieting due to hormones
2. Multiple malaria vaccine offers protection to people most at risk
3. Computer games help people with Parkinsons disease
4. People With Mental Health Issues More Likely to Be Uninsured
5. Researcher identifies autism employment resources, tips for people with autism spectrum disorders
6. We discount the pain of people we dont like
7. Older people are happier in Brazil and South Africa
8. Easily embarrassed? Study finds people will trust you more
9. First detection of pregnancy protein in older people destined for Alzheimers disease
10. People learn while they sleep, study suggests
11. Interactive mobile app from UCSF and QuantiaMD teaches people how to manage diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Some People With Alzheimer's Take Conflicting Drugs
(Date:10/13/2017)... Pa. (PRWEB) , ... October 13, 2017 , ... While ... dark poses a problem. Fortunately, an inventor from Austin, Texas, has identified a solution. ... to medication in darkness or restricted lighting. As such, it eliminates the need to ...
(Date:10/13/2017)... ... ... Lori R. Somekh, founder of the Law Office of Somekh & ... and special needs planning attorneys. “Membership in ElderCounsel helps our office remain up to ... with elder law attorneys nationwide,” said Somekh. , ElderCounsel was founded ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids this ... by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited about ... ages; it is a non-competitive, non-timed event, which is all about having fun and ...
(Date:10/13/2017)... ... , ... “America On The Brink”: the Christian history of the United States ... creation of published author, William Nowers. Captain Nowers and his wife, Millie, have ... thirty years in the Navy. Following his career as a naval aviator and ...
(Date:10/12/2017)... Fla. (PRWEB) , ... October 12, 2017 , ... IsoComforter, ... therapy products, announced today the introduction of an innovative new design of the shoulder ... pad so you get maximum comfort while controlling your pain while using cold therapy. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... -- Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided an ... Puerto Rico , where the company ... Following a comprehensive onsite assessment, ... damage, temporary loss of power and minimal water damage ... operations have resumed, and the company expects to return ...
(Date:10/4/2017)... South Korea , Oct. 4, 2017  South ... its next-generation CPR training aide "cprCUBE" on Kickstarter. The ... chest compression during cardiac arrests with better efficiency compared ... It also offers real-time feedback on efficacy of the ... The crowdfunding campaign has a goal to raise $5,000. ...
(Date:10/2/2017)... , Oct. 2, 2017  AllianceRx Walgreens Prime, the ... by Walgreens and pharmacy benefit manager Prime Therapeutics LLC ... brand, which included the unveiling of new signage at ... as well as at a few other company-owned facilities ... brand to patients, some of whom will begin to ...
Breaking Medicine Technology: