Navigation Links
Some Oral Contraceptives May Reduce Pregnancy Chances in In Vitro Fertilization (IVF), According to New Research by CHR

New York, NY (PRWEB) May 06, 2013

Some oral contraceptives with stronger androgenic characteristics may reduce pregnancy chances with IVF, reports a new study conducted by the Center for Human Reproduction (CHR), a research-driven fertility center in New York City.

The study, just published in Reproductive Biology and Endocrinology(1), investigated 43 young oocyte (egg) donors, some of whom were taking various forms of oral contraceptives. According to the study, donors who took contraceptives with stronger androgenic characteristics before their treatment cycles had significantly lower number of eggs retrieved after ovarian stimulation. Donors who took androgenic contraceptives developed 11 eggs on average, while those with no contraceptives had 16, and those using anti-androgenic contraceptives had 19.

Because oral contraceptives suppress secretion of gonadotropins from the pituitary, hormonal contraceptive use may lead to suppression of ovarian function, interrupting the normal development of eggs in the ovaries. Lower egg yields after ovarian stimulation is also likely to result in lower IVF pregnancy rates.

“Many fertility centers routinely use oral contraceptives in preparatory stages of IVF cycles,” says David H. Barad, MD, MS, Director of Clinical ART and Senior Scientist at CHR, who is the lead author of the study. “Our results show that this routine use of oral contraceptives before IVF may have a negative impact on oocyte numbers, and may require rethinking on the part of treating physicians.

In the study, some hormonal contraceptives’ negative effects on oocyte yields were apparent even in young oocyte donors with normal ovarian reserve. “These negative effects on IVF outcomes may be even greater in women with diminished ovarian reserve,” cautions Dr. Barad, “who already produce only a small number of eggs under the best of circumstances.”

The study is the first to report on the potentially negative effects of at least some hormonal contraceptives on IVF outcomes. Larger studies are needed to determine whether use of some forms of oral contraceptives should be avoided in the context of fertility treatments.

(1)Barad DH, Kim A, Kubba H, Weghofer A and Gleicher N. Does hormonal contraception prior to in vitro fertilization (IVF) negatively affect oocyte yields? – A pilot study. Reprod Biol Endocrinol 2013;11:28.

About Center for Human Reproduction
The Center for Human Reproduction (, located in New York City, is one of the world’s leading fertility centers. As "fertility center of last resort,” CHR has treated countless women with diminished ovarian reserve (DOR), whether due to advanced age or premature ovarian aging (POA). To serve its patient population, Dr. Barad is available for further comments.

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. More Teen Girls Using Contraceptives: CDC
2. Blood Clot Risk Linked to Some Non-Pill Contraceptives
3. 70 percent of women use contraceptives during their first sexual encounter
4. IUDs Safe Contraceptives for Teens, Study Finds
5. Huntingtons Disease Linked to Reduced Cancer Risk in Study
6. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
7. Decision guide reduced uncertainty over breast cancer prevention, study finds
8. Scoliosis Treatment Might Reduce Need for Surgeries
9. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
10. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
11. Groundbreaking Nigeria summit results in major commitment to reduce child deaths
Post Your Comments:
(Date:6/26/2016)... ... ... On June 10-11, 2016, A Forever Recovery, a holistic treatment center for ... Table in Battle Creek, MI, where the rehabilitation facility is located. This annual celebration ... world’s leading providers of cereal and other breakfast foods. Its residents often refer to ...
(Date:6/25/2016)... Washington, D.C. (PRWEB) , ... June 25, 2016 ... ... will discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June ... share their work on several important health care topics including advance care planning, ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... the "Pharmaceutical Excipients Market by Type (Organic Chemical ... Preservative), Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast ... The global pharmaceutical excipients ... 2021 at a CAGR of 6.1% in the forecast ...
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Global MEMS Devices Medical Market Analysis 2016 - Forecast to ... The report contains up to date financial ... reliable analysis. Assessment of major trends with potential impact on ... dive analysis of market segmentation which comprises of sub markets, ...
Breaking Medicine Technology: