Navigation Links
Some Oral Contraceptives May Reduce Pregnancy Chances in In Vitro Fertilization (IVF), According to New Research by CHR
Date:5/6/2013

New York, NY (PRWEB) May 06, 2013

Some oral contraceptives with stronger androgenic characteristics may reduce pregnancy chances with IVF, reports a new study conducted by the Center for Human Reproduction (CHR), a research-driven fertility center in New York City.

The study, just published in Reproductive Biology and Endocrinology(1), investigated 43 young oocyte (egg) donors, some of whom were taking various forms of oral contraceptives. According to the study, donors who took contraceptives with stronger androgenic characteristics before their treatment cycles had significantly lower number of eggs retrieved after ovarian stimulation. Donors who took androgenic contraceptives developed 11 eggs on average, while those with no contraceptives had 16, and those using anti-androgenic contraceptives had 19.

Because oral contraceptives suppress secretion of gonadotropins from the pituitary, hormonal contraceptive use may lead to suppression of ovarian function, interrupting the normal development of eggs in the ovaries. Lower egg yields after ovarian stimulation is also likely to result in lower IVF pregnancy rates.

“Many fertility centers routinely use oral contraceptives in preparatory stages of IVF cycles,” says David H. Barad, MD, MS, Director of Clinical ART and Senior Scientist at CHR, who is the lead author of the study. “Our results show that this routine use of oral contraceptives before IVF may have a negative impact on oocyte numbers, and may require rethinking on the part of treating physicians.

In the study, some hormonal contraceptives’ negative effects on oocyte yields were apparent even in young oocyte donors with normal ovarian reserve. “These negative effects on IVF outcomes may be even greater in women with diminished ovarian reserve,” cautions Dr. Barad, “who already produce only a small number of eggs under the best of circumstances.”

The study is the first to report on the potentially negative effects of at least some hormonal contraceptives on IVF outcomes. Larger studies are needed to determine whether use of some forms of oral contraceptives should be avoided in the context of fertility treatments.

(1)Barad DH, Kim A, Kubba H, Weghofer A and Gleicher N. Does hormonal contraception prior to in vitro fertilization (IVF) negatively affect oocyte yields? – A pilot study. Reprod Biol Endocrinol 2013;11:28.

About Center for Human Reproduction
The Center for Human Reproduction (https://www.centerforhumanreprod.com/), located in New York City, is one of the world’s leading fertility centers. As "fertility center of last resort,” CHR has treated countless women with diminished ovarian reserve (DOR), whether due to advanced age or premature ovarian aging (POA). To serve its patient population, Dr. Barad is available for further comments.

Read the full story at http://www.prweb.com/releases/pregnancychanceswithivf/birthcontrol/prweb10701484.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. More Teen Girls Using Contraceptives: CDC
2. Blood Clot Risk Linked to Some Non-Pill Contraceptives
3. 70 percent of women use contraceptives during their first sexual encounter
4. IUDs Safe Contraceptives for Teens, Study Finds
5. Huntingtons Disease Linked to Reduced Cancer Risk in Study
6. BMC study shows diverting passengers to elevators could help reduce falls at Logan Airport
7. Decision guide reduced uncertainty over breast cancer prevention, study finds
8. Scoliosis Treatment Might Reduce Need for Surgeries
9. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
10. Additional blood pressure screening may reduce incidence of CVD events and death by up to 3 percent
11. Groundbreaking Nigeria summit results in major commitment to reduce child deaths
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder ... of ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership ... rules. It also provides a forum to network with elder law attorneys nationwide,” said ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one ... an innovative new design of the shoulder pad. The shoulder pad provides optimal ... controlling your pain while using cold therapy. By utilizing ice and water that is ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)...  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), today provided ... Piedras, Puerto Rico , where the ... Following a comprehensive onsite ... structural damage, temporary loss of power and minimal water ... manufacturing operations have resumed, and the company expects to ...
(Date:10/10/2017)... Oct. 10, 2017   West Pharmaceutical Services, Inc. ... for injectable drug administration, today shared the results of ... for improving the intradermal administration of polio vaccines. The ... Summit in May 2017 by Dr. Ondrej Mach ... World Health Organization (WHO), and recently published in the ...
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
Breaking Medicine Technology: