Navigation Links
Some Antibiotics, Blood Pressure Meds a Bad Mix: Study
Date:1/17/2011

hat they interfere with an enzyme in the liver that is needed to break down the calcium channel blocker. When this enzyme is "turned off," too much of the calcium blocker accumulates and causes blood pressure to drop dangerously low, Juurlink explained.

Dr. Barry J. Materson, a professor of medicine at the University of Miami Miller School of Medicine and a specialist in blood pressure, said that this study "is of practical interest."

The researchers have established that the combination of a macrolide antibiotic and a calcium channel blocker can cause hypotension or even shock because of increased blood levels of the calcium channel blocker, Materson said.

"This happens because of the interference with an enzyme that metabolizes the calcium blocker," Materson noted.

Materson added that grapefruit juice can also interfere with the same enzyme and lead to elevated levels of calcium channel blockers. "Grapefruit juice is consumed much more frequently than macrolide antimicrobials," he pointed out.

One limitation of the study is not knowing how many of these patients had hypotension or shock from the infection for which they were receiving the antibiotic. "We also do not know how many, if any, consume grapefruit juice," Materson said.

"Nevertheless, it is important for practitioners, pharmacists and patients to appreciate that both grapefruit juice and macrolide antibiotics, with the possible exception of azithromycin, can increase the blood level of the calcium channel blockers to an unpredictable degree and may rarely result in hypotension or even shock," he said.

More information

For more information on drug interactions, visit the U.S. Food and Drug Administration.

SOURCES: David Juurlink, M.D., Ph.D., scientist, Sunnybrook Research Institute, Toronto; Barry J. Materson, M.D., professor, medicine, Uni
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Smarten Up About Antibiotics, CDC Urges
2. Blood Type O Associated With Less Risk for Heart Attack
3. Bioactive compounds in berries can reduce high blood pressure
4. Room light before bedtime may impact sleep quality, blood pressure and diabetes risk
5. International research team reports major findings in prevention and treatment of blood clots
6. UNC researchers inch closer to unlocking potential of synthetic blood
7. Secondhand Smoke Tied to High Blood Pressure in Kids
8. Embryonic stem cells help deliver good genes in a model of inherited blood disorder
9. Immune Disorders May Raise Blood Clot Risk in Hospitalized Patients
10. Engineering team invents lab-on-a-chip for fast, inexpensive blood tests
11. Early Steps Toward an Alzheimers Blood Test
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Some Antibiotics, Blood Pressure Meds a Bad Mix: Study
(Date:10/19/2014)... been working in the garment industry for decades, LunaDress’ dress ... James, one of the company’s top designers, many ladies like ... that add beauty to them. Chiffon floor length outfits are ... new selection of 2014 long prom dresses. , As ... available in over 20 popular designs. The company intends to ...
(Date:10/19/2014)... 20, 2014 Recently, Fancyflyingfox.com, an innovative ... clothes, has announced its latest designs of 2014 ... the new elegant outfits are offered with big discounts, ... order before October 30 can enjoy this special offer. ... marketing strategies, it has become one of the leading ...
(Date:10/19/2014)... (PRWEB) October 19, 2014 Visual ... program has just been released to the public ... online body building and fitness community. The commotion ... of DietsAndFitnessGuides.com's Vin Delmonico prompting an investigative review. ... of hitting what is commonly known as a ...
(Date:10/19/2014)... 2014 (HealthDay News) -- New stem cell-based research could ... new treatments, a new study suggests. Scientists used ... tissue in a lab dish. They then transplanted the ... intestinal disorders, according to the researchers. "This provides ... conditions that can cause intestinal failure, from genetic disorders ...
(Date:10/19/2014)... 20, 2014 – The U.S. Government has initiated ... Alzheimer,s disease by 2025. However, a workgroup of ... research milestones in the U.S. Government,s National Plan ... scope, increased in scale, and adequately funded in ... of proposals by the workgroup to enlarge and ...
Breaking Medicine News(10 mins):Health News:2014 Long Prom Dresses From LunaDress Now Available In Over 20 Popular Designs 2Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2Health News:Scientists Grow, Implant Human Intestinal Tissue in Mice 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6
... MA Coronary heart disease (CHD) is the leading cause ... and economic costs, especially among older adults. It has ... least in middle-aged, low- and moderate-risk white men. Now ... Journal of the American College of Cardiology reports ...
... "Performance Excellence and Accountability in Kidney Care" to reduce mortality by ... , , WASHINGTON, June 8 ... campaign pledging to reduce mortality among first-year dialysis patients - those ... by 20 percent by the end of 2012. , ...
... electrical stimulation to prevent airway closure during sleep , ... Inc., a private medical device company, today announced it ... Earlier in 2009, Inspire announced the first human ... Obstructive Sleep Apnea (OSA). Since this announcement, Inspire ...
... depression and anxiety, research suggests , MONDAY, June 8 (HealthDay ... caregivers who may need a break. For children aged 4 ... help reduce hyperactivity, anxiety and depression, new study findings show. ... napping (77 percent) or non-napping (23 percent), researchers found that ...
... SEEKS INVOLVEMENT ACROSS THE UNITED STATES; ASKS PUBLIC TO DIRECT ... June 8 Tom,s of Maine introduces 50 States for ... difference in their communities. The national program asks the public ... lasting, positive change. , , Tom,s of Maine ...
... of Arts and Sciences has published a volume of ... Questions," examining the scientific support for using functional magnetic ... seven essays, authored by scholars of neuroscience, law, and ... when machine-based means are employed to identify deceit. ...
Cached Medicine News:Health News:Cardiac rehabilitation saves lives 2Health News:Rep. Lewis Commends Kidney Care Partners' Health Care Campaign to Improve Survival Rates of First-Year Dialysis Patients in Georgia 2Health News:Rep. Lewis Commends Kidney Care Partners' Health Care Campaign to Improve Survival Rates of First-Year Dialysis Patients in Georgia 3Health News:Inspire Medical Systems Completes $17 Million Series B Financing 2Health News:Inspire Medical Systems Completes $17 Million Series B Financing 3Health News:Tom's of Maine Invites Public Participation in 50 States for Good Program 2Health News:New essays examine the use of fMRI to recognize deceit 2
(Date:10/20/2014)... Oct. 20, 2014 Pharmaceutic Labs announces the ... Albany, NY for admixing, compounding, ... meets and/or exceeds the FDA standards for safety and ... Part 211. The 10,000 square foot ... of quality assurance and quality control. The company will ...
(Date:10/19/2014)... Wash. , Oct. 20, 2014 CTI ... that it will report its third quarter 2014 financial ... of the U.S. financial markets. Following the announcement, members ... call to discuss the results and provide a general ... Access to the event can be obtained as follows: ...
(Date:10/17/2014)... , Oct. 17, 2014  Training market ... a critical success factor in today,s highly competitive ... market research organizations that effectively and efficiently produce ... or service area. Effective training ... and earn recognition from internal clients by developing ...
Breaking Medicine Technology:CTI BioPharma to Report Third Quarter 2014 Financial Results on October 29, 2014 2Effective Training Programs for Market Research Groups can Boost Overall Organizational Success 2
... Keystone Symposia HIV Pathogenesis Conference, SAN ... ANX ) announced that it presented ... product candidate at the,Keystone Symposia HIV Pathogenesis ... The preclinical results demonstrate a unique resistance ...
... question with today,s ... ... uses a combination of catheter-mounted balloons and stents,to open a completely ... the best treatment for heart attack when performed rapidly.,However, few hospitals ...
Cached Medicine Technology:ANX-201 Demonstrates a Unique Resistance Profile in Preclinical Tests 2ANX-201 Demonstrates a Unique Resistance Profile in Preclinical Tests 3ANX-201 Demonstrates a Unique Resistance Profile in Preclinical Tests 4Is PCI Safe, Effective After Clot-Busters for Heart Attack? 2Is PCI Safe, Effective After Clot-Busters for Heart Attack? 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: