Navigation Links
Some Antibiotics, Blood Pressure Meds a Bad Mix: Study
Date:1/17/2011

hat they interfere with an enzyme in the liver that is needed to break down the calcium channel blocker. When this enzyme is "turned off," too much of the calcium blocker accumulates and causes blood pressure to drop dangerously low, Juurlink explained.

Dr. Barry J. Materson, a professor of medicine at the University of Miami Miller School of Medicine and a specialist in blood pressure, said that this study "is of practical interest."

The researchers have established that the combination of a macrolide antibiotic and a calcium channel blocker can cause hypotension or even shock because of increased blood levels of the calcium channel blocker, Materson said.

"This happens because of the interference with an enzyme that metabolizes the calcium blocker," Materson noted.

Materson added that grapefruit juice can also interfere with the same enzyme and lead to elevated levels of calcium channel blockers. "Grapefruit juice is consumed much more frequently than macrolide antimicrobials," he pointed out.

One limitation of the study is not knowing how many of these patients had hypotension or shock from the infection for which they were receiving the antibiotic. "We also do not know how many, if any, consume grapefruit juice," Materson said.

"Nevertheless, it is important for practitioners, pharmacists and patients to appreciate that both grapefruit juice and macrolide antibiotics, with the possible exception of azithromycin, can increase the blood level of the calcium channel blockers to an unpredictable degree and may rarely result in hypotension or even shock," he said.

More information

For more information on drug interactions, visit the U.S. Food and Drug Administration.

SOURCES: David Juurlink, M.D., Ph.D., scientist, Sunnybrook Research Institute, Toronto; Barry J. Materson, M.D., professor, medicine, Uni
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Smarten Up About Antibiotics, CDC Urges
2. Blood Type O Associated With Less Risk for Heart Attack
3. Bioactive compounds in berries can reduce high blood pressure
4. Room light before bedtime may impact sleep quality, blood pressure and diabetes risk
5. International research team reports major findings in prevention and treatment of blood clots
6. UNC researchers inch closer to unlocking potential of synthetic blood
7. Secondhand Smoke Tied to High Blood Pressure in Kids
8. Embryonic stem cells help deliver good genes in a model of inherited blood disorder
9. Immune Disorders May Raise Blood Clot Risk in Hospitalized Patients
10. Engineering team invents lab-on-a-chip for fast, inexpensive blood tests
11. Early Steps Toward an Alzheimers Blood Test
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Some Antibiotics, Blood Pressure Meds a Bad Mix: Study
(Date:10/30/2014)... October 30, 2014 PreDiabetes Centers ... PreD Store shoppers with a supply of sugardown®, ... to reduce post-meal blood sugar spikes. Learning how to ... an important part of a diabetes prevention plan. , ... receive one complimentary tube of sugardown. The offer expires ...
(Date:10/30/2014)... Reinberg HealthDay Reporter , WEDNESDAY, ... men with prostate cancer who also have certain heart problems ... a new study suggests. , , The therapy in question is ... to reduce levels of male hormones to prevent the growth ... current research, this hormone therapy was linked to triple the ...
(Date:10/30/2014)... Toronto, Canada (PRWEB) October 30, 2014 ... the area’s leading provider of non-medical, in-home senior care, ... activity to increased brain health. , The study, performed ... the ages of 60 and 78 over a week-long ... as opposed to daily physical activity. By examining the ...
(Date:10/30/2014)... 30, 2014 Global prebiotics market is ... to a new study by Grand View Research, Inc. ... for sugar and fat free products owing to increased ... for prebiotics over the forecast period. , View full ... Food & beverage was the largest application segment with ...
(Date:10/30/2014)... South Carolina (PRWEB) October 30, 2014 ... and should be more vigorously exercised to help maintain ... recently authored the book ‘Dementia Express: Lose Your Memory ... book uses counterintuitive reasoning and sometimes conflicting attitudes to ... course for the mind, a reader must decipher the ...
Breaking Medicine News(10 mins):Health News:PreDiabetes Treatment Company Offers PreD Store Shoppers Supplements to Support Healthy Blood Sugar 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 3Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 2Health News:Home Care Assistance – Halton/Peel Region, a Top Provider of In-Home Care, Responds to Study Linking Exercise to Healthier Senior Brains 3Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 2Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 3Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 4Health News:Prebiotics Market Is Expected To Grow At A CAGR Of 9.3% From 2014 To 2020: Grand View Research, Inc. 5Health News:‘Dementia Express’ Offers Contradictory and Sometimes Reverse Thinking, All to Keep its Reader on Their Toes With an Active Mind. 2
... -- Winner Medical Group Inc.,(OTC Bulletin Board: WMDG) (,Winner Medical, ... quarter ended December 31,2008. The Company,s results are detailed in ... Exchange Commission. , , First Quarter 2009 ... by 33.14% over the first quarter of, ...
... development, today announces that it has appointed Riccardo Nisato, MBA, PhD, ... CH. Dr. Nisato will be responsible for replicating Stemedica,s U.S. ... , ... San Diego, Calif. (PRWEB) February 13, 2009 -- ...
... Feb. 12 The Ensign Group, Inc. (Nasdaq: ... the Ensign(TM) group of skilled nursing, rehabilitative care ... it expects to issue its fourth quarter and ... close on Wednesday, February 18, 2009.(Logo: ...
... and Valentine,s Day LOS ANGELES, Feb. 12 Don,t ... In celebration of National Condom Week, Planned Parenthood Los ... application on Facebook to help remind everyone -- and ... against sexually transmitted diseases (STDs) and unplanned pregnancy. " ...
... , , THURSDAY, Feb. 12 (HealthDay News) -- People exposed ... 44 percent increased risk of developing dementia, a new ... connection between smoking and increased risk for dementia and ... to date showing a link between secondhand smoke and ...
... legislation intended to help reduce cardiovascular disease in ... that could force some women to make tough ... Lisa Murkowski (R-AK) and Congresswomen Lois Capps (D-CA) ... that would expand access to screening and lifestyle ...
Cached Medicine News:Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 2Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 3Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 4Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 5Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 6Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 7Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 8Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 9Health News:Winner Medical Reports First Quarter Fiscal 2009 Results 10Health News:Stemedica Announces the Appointment of Riccardo Nisato, MBA, PhD as Director of Manufacturing and Clinical Business Development for Stemedica International 2Health News:Stemedica Announces the Appointment of Riccardo Nisato, MBA, PhD as Director of Manufacturing and Clinical Business Development for Stemedica International 3Health News:The Ensign Group Schedules 2008 Year End Earnings Call for Thursday, February 19, 2009 2Health News:Planned Parenthood Offers E-Condoms on Facebook 2Health News:Secondhand Smoke Linked to Dementia 2Health News:Stabenow, Murkowski, Capps and Bono Mack Reintroduce HEART for Women Act 2Health News:Stabenow, Murkowski, Capps and Bono Mack Reintroduce HEART for Women Act 3Health News:Stabenow, Murkowski, Capps and Bono Mack Reintroduce HEART for Women Act 4
(Date:10/30/2014)... Oct. 30, 2014 Molecular Profiles Ltd., a ... ) and Maryland -based Xceleron have ... efficiency during clinical development that will be launched at ... week. This partnership extends Molecular Profiles, new ... launched earlier this month. The company also has complementary ...
(Date:10/30/2014)... October 30, 2014 ... beim Aufbau von Kuhmilchverträglichkeit     Kuhmilchproteinallergie ... bei Säuglingen und Kleinkindern. Der bisher übliche ... Ernährung der Babys bzw. deren stillenden Mütter ... dass sich bei einer beträchtlichen Anzahl von ...
(Date:10/30/2014)... 29, 2014 nebulizer is a medical device ... and cystic fibrosis) that converts liquid medication into mist ... the lungs of a patient when inhaled through the ... is dominated by various devices powered by electric current ... asthma, COPD and cystic fibrosis and growing number of ...
Breaking Medicine Technology:Molecular Profiles To Launch US Strategic Alliance At AAPS 2Molecular Profiles To Launch US Strategic Alliance At AAPS 3Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 2Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 3Nebulizers Market (Pneumatic Nebulizers, Ultrasonic Nebulizers and Mesh Nebulizers) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019 2Nebulizers Market (Pneumatic Nebulizers, Ultrasonic Nebulizers and Mesh Nebulizers) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019 3
... Langan, Vice President of Marketing and Business Development, announced ... labeling for sterile intravenous compounded ICU Services at ... May 19-24, 2012 in Orlando, Florida. (Logo: ... care professionals to visit Booth #2668 to see how ...
...  Varian Medical Systems (NYSE: VAR ) will ... and other conditions non-invasively at the 2012 International Conference ... in San Francisco.  "We,re excited about ... not be familiar with radiosurgery as a treatment option ...
Cached Medicine Technology:PharMEDium Highlights Enhanced Labeling for ICU Services at Critical Care Expo 2Varian Medical Systems to Showcase Radiosurgery Technology for Non-invasive Treatment of Early Stage Inoperable Lung Cancer 2Varian Medical Systems to Showcase Radiosurgery Technology for Non-invasive Treatment of Early Stage Inoperable Lung Cancer 3Varian Medical Systems to Showcase Radiosurgery Technology for Non-invasive Treatment of Early Stage Inoperable Lung Cancer 4
Inquire...
Inquire...
Inquire...
... Recognized for classic styling, Tura's original ... women with discriminating taste. Tura designs exemplify ... beauty and style with quality and durability. ... details set the Tura woman apart. Rich ...
Medicine Products: