Navigation Links
Solid-pseudopapillary neoplasm of the pancreas or pancreatic endocrine tumor?
Date:3/17/2010

Solid-pseudopapillary neoplasm (SPN) of the pancreas is relatively rare. There are some similarities between SPN and pancreatic endocrine tumor (PET), especially the non-functioning ones, in clinical and pathological manifestations. Even the results of immunohistochemistry reported in the literature showed that the expression profiles of the two tumors overlapped, which sometimes results in difficulty distinguishing the two entities. In recent years, studies have shown that the vast majority of SPN harbor a point mutation on exon 3 of β-catenin gene, which has not yet been discovered in other pancreas tumors.

A research article published on February 28, 2010 in the World Journal of Gastroenterology addresses this question. A total of 24 cases pathologically diagnosed as SPN or PET, including 10 SPN and 14 PET, were reviewed.

Their results showed SPN of the pancreas, compared with PET, is a cystic-solid or cystic tumor with a larger size mostly seen in young women, and has the morphological features of hemorrhage and necrosis on the cut surface and exclusive pseudopapillary structures on light microscopy caused by cellular dyscohesive degeneration. If necessary, immunostaining of b-catenin and E-cadherin is quite helpful to make the differential diagnosis.


'/>"/>

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. A long-term survival offered by resection of solid-pseudopapillary tumor of the pancreas?
2. What are simple ways to judge the efficacy of 5-fluorouracil in colonic neoplasm?
3. Fudan-Cinpathogen Study Shows Chronic Lymphoid Neoplasms are More Common in Shanghai Than Thought
4. Imaging features of intraductal papillary mucinous neoplasms of the pancreas
5. Circulating fats kill transplanted pancreas cells, study shows
6. Pancreas May Be Key to Pregnancy-Linked Diabetes
7. Stem Cells Finally Found in Pancreas
8. A tumor of the pancreas mimicked by colonic duplication?
9. Laparoscopic Surgery on Pancreas Has Fewer Complications
10. Minimally invasive pancreas surgery leads to fewer complications, study finds
11. Combo Kidney-Pancreas Transplant Boosts Survival in Diabetics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... 2016 , ... People across the U.S. are sharpening their pencils and honing ... contest in which patients and their families pay tribute to a genetic counselor by ... Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In ...
(Date:6/24/2016)... Nevada (PRWEB) , ... June 24, 2016 , ... ... Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations ... in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a ...
(Date:6/24/2016)... ... 24, 2016 , ... Venture Construction Group (VCG) sponsors Luke’s Wings ... 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. ... service members that have been wounded in battle and their families. Venture Construction Group ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
(Date:6/23/2016)... , June 23, 2016 Research ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, Petrochemical, ... (Oral, Topical, Coating, Parenteral) - Global Forecast to 2021" ... The global pharmaceutical excipients market is ... a CAGR of 6.1% in the forecast period 2016 ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology: