Navigation Links
Solid-pseudopapillary neoplasm of the pancreas or pancreatic endocrine tumor?
Date:3/17/2010

Solid-pseudopapillary neoplasm (SPN) of the pancreas is relatively rare. There are some similarities between SPN and pancreatic endocrine tumor (PET), especially the non-functioning ones, in clinical and pathological manifestations. Even the results of immunohistochemistry reported in the literature showed that the expression profiles of the two tumors overlapped, which sometimes results in difficulty distinguishing the two entities. In recent years, studies have shown that the vast majority of SPN harbor a point mutation on exon 3 of β-catenin gene, which has not yet been discovered in other pancreas tumors.

A research article published on February 28, 2010 in the World Journal of Gastroenterology addresses this question. A total of 24 cases pathologically diagnosed as SPN or PET, including 10 SPN and 14 PET, were reviewed.

Their results showed SPN of the pancreas, compared with PET, is a cystic-solid or cystic tumor with a larger size mostly seen in young women, and has the morphological features of hemorrhage and necrosis on the cut surface and exclusive pseudopapillary structures on light microscopy caused by cellular dyscohesive degeneration. If necessary, immunostaining of b-catenin and E-cadherin is quite helpful to make the differential diagnosis.


'/>"/>

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. A long-term survival offered by resection of solid-pseudopapillary tumor of the pancreas?
2. What are simple ways to judge the efficacy of 5-fluorouracil in colonic neoplasm?
3. Fudan-Cinpathogen Study Shows Chronic Lymphoid Neoplasms are More Common in Shanghai Than Thought
4. Imaging features of intraductal papillary mucinous neoplasms of the pancreas
5. Circulating fats kill transplanted pancreas cells, study shows
6. Pancreas May Be Key to Pregnancy-Linked Diabetes
7. Stem Cells Finally Found in Pancreas
8. A tumor of the pancreas mimicked by colonic duplication?
9. Laparoscopic Surgery on Pancreas Has Fewer Complications
10. Minimally invasive pancreas surgery leads to fewer complications, study finds
11. Combo Kidney-Pancreas Transplant Boosts Survival in Diabetics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... ... March 27, 2017 , ... A study by the founder of ... colleague, Sudeep Roy, MD, was recently published in the American Journal of Cosmetic ... details Drs. Buckingham and Roy’s study on the use of Electro Lube during the ...
(Date:3/27/2017)... Scottsdale, Arizona (PRWEB) , ... March 27, 2017 , ... ... in the top 10 for Rent the Runway Foundation and UBS’ Project Entrepreneur. Mayo ... New York on April 8. , Project Entrepreneur’s second annual venture competition ignites ...
(Date:3/27/2017)... Niles, IL (PRWEB) , ... March 27, 2017 ... ... testing systems, recently received the CE Certificate of Conformity for the Smart System® ... meet or exceed the highest industry standards and specifications such as ANSI, ISO ...
(Date:3/27/2017)... ... March 27, 2017 , ... ... and conference coverage on veterinary medicine, announces the launch of Veterinarian’s Money Digest™, ... packaged with the April edition of American Veterinarian™. , “We look ...
(Date:3/27/2017)... Orion, Michigan (PRWEB) , ... March 27, 2017 ... ... results. The comprehensive weight management program at Women’s Excellence will help patients ... initial evaluation and physical exam. The specialists at Women's Excellence will measure ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... 2017 To mark the end of Save Your ... leader in digital imaging solutions, will showcase Canon eye care ... New York,s Jacob Javits Center from ... sponsored by the American Optometric Association, is observed annually in ... comprehensive eye exams. In recognition of this observance, Canon ...
(Date:3/27/2017)... British Columbia, March 27, 2017  Sophiris Bio ... or "Sophiris"), a clinical late-stage biopharmaceutical company developing ... urological diseases, today reported fourth quarter and full ... Key Corporate Highlights: ... Localized Prostate Cancer. During 2016, the Company reported ...
(Date:3/27/2017)... March 27, 2017 BioLineRx Ltd. (NASDAQ/TASE: ... announced today that AGI-134, an immunotherapy for the treatment of ... Ltd., will be featured at the upcoming American Association ... Washington, DC to be held on April 1-5, ... ...
Breaking Medicine Technology: