Navigation Links
Solid-pseudopapillary neoplasm of the pancreas or pancreatic endocrine tumor?
Date:3/17/2010

Solid-pseudopapillary neoplasm (SPN) of the pancreas is relatively rare. There are some similarities between SPN and pancreatic endocrine tumor (PET), especially the non-functioning ones, in clinical and pathological manifestations. Even the results of immunohistochemistry reported in the literature showed that the expression profiles of the two tumors overlapped, which sometimes results in difficulty distinguishing the two entities. In recent years, studies have shown that the vast majority of SPN harbor a point mutation on exon 3 of β-catenin gene, which has not yet been discovered in other pancreas tumors.

A research article published on February 28, 2010 in the World Journal of Gastroenterology addresses this question. A total of 24 cases pathologically diagnosed as SPN or PET, including 10 SPN and 14 PET, were reviewed.

Their results showed SPN of the pancreas, compared with PET, is a cystic-solid or cystic tumor with a larger size mostly seen in young women, and has the morphological features of hemorrhage and necrosis on the cut surface and exclusive pseudopapillary structures on light microscopy caused by cellular dyscohesive degeneration. If necessary, immunostaining of b-catenin and E-cadherin is quite helpful to make the differential diagnosis.


'/>"/>

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. A long-term survival offered by resection of solid-pseudopapillary tumor of the pancreas?
2. What are simple ways to judge the efficacy of 5-fluorouracil in colonic neoplasm?
3. Fudan-Cinpathogen Study Shows Chronic Lymphoid Neoplasms are More Common in Shanghai Than Thought
4. Imaging features of intraductal papillary mucinous neoplasms of the pancreas
5. Circulating fats kill transplanted pancreas cells, study shows
6. Pancreas May Be Key to Pregnancy-Linked Diabetes
7. Stem Cells Finally Found in Pancreas
8. A tumor of the pancreas mimicked by colonic duplication?
9. Laparoscopic Surgery on Pancreas Has Fewer Complications
10. Minimally invasive pancreas surgery leads to fewer complications, study finds
11. Combo Kidney-Pancreas Transplant Boosts Survival in Diabetics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best Buy Eyeglasses, ... the United States and Canada wear eyeglasses. Once considered to be a purely functional ... a fashion statement. Even celebrities use glasses as a way of creating an iconic ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many ... been diagnosed with endometriosis. These women need a treatment plan to not only ... approach that can help for preservation of fertility and ultimately achieving a pregnancy. ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... Austin ... of the American College of Mohs Surgery and to Dr. Russell Peckham for medical ... and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 One of ... has announced the formation of a new biotechnology company, Noxopharm Limited ... $6m in an IPO and to list on the ASX. ... candidate, NOX66, ready to enter a Phase 1 clinical study later ... designed to address one of the biggest problems facing cancer patients ...
(Date:6/26/2016)... Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) announced ... Act of 1976, as amended ("HSR"), with respect to ... CPXX ) expired effective June 24, 2016, ... previously announced on May 31, 2016, Jazz Pharmaceuticals and ... Jazz Pharmaceuticals has commenced a tender offer for all ...
(Date:6/26/2016)...  VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) reported ... required to build a strong and stable market for ... on the OTC Markets-pink current trading platform. ... are seeing an anomaly in market trading activities that ... the Company, but shareholders and market players as well. ...
Breaking Medicine Technology: