Navigation Links
Sodium buildup in brain linked to disability in multiple sclerosis
Date:7/16/2012

lop techniques to perform 3T sodium MRI on patients," Dr. Zaaraoui said. "To better understand this disease, we need to probe new molecules. The time has come for probing brain sodium concentrations."

Using specially developed hardware and software, the researchers conducted sodium MRI on 26 MS patients, including 14 with early-stage RRMS (less than five years in duration) and 12 with advanced disease (longer than five years), and 15 age- and sex-matched control participants.

In the early-stage RRMS patients, sodium MRI revealed abnormally high concentrations of sodium in specific brain regions, including the brainstem, cerebellum and temporal pole. In the advanced-stage RRMS patients, abnormally high sodium accumulation was widespread throughout the whole brain, including normal appearing brain tissue.

"In RRMS patients, the amount of sodium accumulation in gray matter associated with the motor system was directly correlated to the degree of patient disability," Dr. Zaaraoui said.

Current treatments for MS are only able to slow the progress of the disease. The use of sodium accumulation as a biomarker of neuron degeneration may assist pharmaceutical companies in developing and assessing potential treatments.

"Brain sodium MR imaging can help us to better understand the disease and to monitor the occurrence of neuronal injury in MS patients and possibly in patients with other brain disorders," Dr. Ranjeva said.


'/>"/>
Contact: Linda Brooks
lbrooks@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Poor Sleep May Age Your Brain
2. Low-cal diets effects seen in fly brain, mouthpart
3. Brain power shortage
4. Exercise Can Shield the Aging Brain, Studies Show
5. Mayo Clinic creates tool to track real-time chemical changes in brain
6. The Ben & Catherine Ivy Foundation contributes $10 million to TGen for brain cancer research
7. Brain Scans Using New Dye May Predict Alzheimers
8. Strong communication between brain and muscle requires both having the protein LRP4
9. Better treatment for brain cancer revealed by new molecular insights
10. Pediatric tumors traced to stem cells in developing brain​​
11. Electrical brain stimulation can alleviate swallowing disorders after stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... (PRWEB) August 30, 2014 Serving contented ... in India, Profit By Outsourcing is now offering ... services. The company gives emphasize on putting forward the ... product to clients. Their dedicated team of professionals and ... results. They can handle even the critical issues of ...
(Date:8/30/2014)... 30, 2014 "I had a handicapped friend ... crutches," said an inventor from Wetumpka, Ala. "In order to ... of the shore, I came up with a way for ... created a prototype for the patent-pending Deezers to allow crutches ... individual to use crutches, walkers, or canes at the beach. ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 In today’s ... and increasingly difficult to get. Snoring and sleep apnea ... and breathing stops) robs people and their bed partners ... challenges. Up to 45% of the population snores and ... sleep apnea. Of these, only 10% have been diagnosed ...
(Date:8/30/2014)... The new review published by Daily Gossip ... Karen Brimeyer, who wanted to make her guide accessible to ... is now easy to find in the form of an ... the author of the new method shares all her tips ... writes in its review that the leaky gut syndrome can ...
(Date:8/30/2014)... 2014 LiveStreamingFitness.com, a company dedicated to providing ... lifestyle resources, is proud to announce it has been recognized ... home fitness solutions by ABC’s Good Morning America. ... ABC’s Good Morning America, “Live Streaming Fitness is the hottest ... day by streamlining your workout…to boot camp at Life Streaming ...
Breaking Medicine News(10 mins):Health News:Profit By Outsourcing Offering Discount for Labor Day on all Web Development Services 2Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Leaky Gut Cure Review Reveals Unique Method to Stop Chronic Symptoms 2Health News:LiveStreamingFitness.com is New Trend In Fitness 2
... System for Rapid Testing for Infectious Diseases Incorporates the ... ARBOR, Mich., May 18 BD Diagnostics, a segment ... BDX ), and HandyLab, Inc. announced today that they ... commercialize its molecular assays on a new BD MAX(TM) ...
... Payment Support Insurance Industry Corporate GreeningSAN DIEGO and ... a leading provider of medical cost containment, provider ... over 70% of U.S. automotive insurance payers, and ... and Gateway Services to Workers, Compensation, Auto Medical ...
... be presented on Abbott,s market-leading XIENCE V(R) stent- Educational ... stent in developmentBARCELONA, Spain, May 18 Abbott (NYSE: ... of major events and news announcements during EuroPCR 2009 ... presentation of new data from the SPIRIT V post-approval, ...
... and PrEP Research and Calls for Urgent Coordination and Leadership ... "It,s an exciting time in HIV prevention research. We will ... research trials this year, as well as see the start ... answers in the years to come," said Mitchell Warren, AVAC ...
... SAN DIEGOCystic fibrosis patients may benefit from a new ... mucous, which is a key factor in the disease, ... The research will be presented on Sunday, May 17, ... San Diego., "Our results suggest that we have identified ...
... help physicians solve a perennial problem: patients who don,t ... the Kaiser Permanente Center for Health Research, in Portland, ... patients with asthma to fill or refill their prescriptions ... be presented on May 17 at the 105th International ...
Cached Medicine News:Health News:BD and HandyLab Announce Exclusive Collaboration to Commercialize Molecular Assays 2Health News:BD and HandyLab Announce Exclusive Collaboration to Commercialize Molecular Assays 3Health News:BD and HandyLab Announce Exclusive Collaboration to Commercialize Molecular Assays 4Health News:Mitchell and Jopari Say 'Green Transaction Initiatives' Play Key Role in P&C and Group Health Industry Environmental Best Practices 2Health News:Mitchell and Jopari Say 'Green Transaction Initiatives' Play Key Role in P&C and Group Health Industry Environmental Best Practices 3Health News:Mitchell and Jopari Say 'Green Transaction Initiatives' Play Key Role in P&C and Group Health Industry Environmental Best Practices 4Health News:Abbott Announces EuroPCR 2009 Activities 2Health News:Abbott Announces EuroPCR 2009 Activities 3Health News:Abbott Announces EuroPCR 2009 Activities 4Health News:Piecing Together the HIV Prevention Puzzle 2Health News:Piecing Together the HIV Prevention Puzzle 3Health News:Piecing Together the HIV Prevention Puzzle 4Health News:Sodium channel blocker shows promise as a potential treatment for cystic fibrosis 2Health News:Increasing ICS compliance: The voice may be recorded, but the results are real 2Health News:Increasing ICS compliance: The voice may be recorded, but the results are real 3
(Date:8/29/2014)... 2014 According to a ... Extraction type (SFE, Cold Pressed, Organic Solvent, & Others), ... Food Supplements, Fragrance, & Others) - Global Trends & ... segments the Amaranth Seed Oil Market with an ... terms of value. The Amaranth Seed Oil Market ...
(Date:8/29/2014)... SPRING, Md. , Aug. 29, 2014  United ... that the U.S. District Court for the District of ... its favor in the company,s case against Sandoz, Inc. ... Judge Peter Sheridan ruled that U.S. Patent ... Inc., and enjoined Sandoz from marketing its generic product ...
(Date:8/29/2014)... Aug. 29, 2014 Diseases largely eradicated in ... ago are returning. Measles was declared eliminated in 2000, ... as of August 15—the highest incidence in 20 years. ... department declared whooping cough a problem of "epidemic ... sick and dying from these preventable diseases—in part because ...
Breaking Medicine Technology:Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4District Court Decision Received In Remodulin Patent Case 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 2Vaccines at the Crossroads: Outbreaks On the Rise Across America 3
... Oct. 10, 2011 IRIDEX Corporation (Nasdaq: IRIX ... named President and Chief Executive Officer effective today. Dr. Beck ... become Chief Technology Officer, and will also replace Mr. Boutacoff ... 47, has spent the majority of his career in leadership ...
... Cantel Medical Corp. (NYSE: CMN ) will ... ended July 31, 2011 on Thursday, October 13 before the ... results at 11:00 AM ET.  Participating in the call will ... CEO; Seth R. Segel, Executive Vice President; and Craig A. ...
Cached Medicine Technology:IRIDEX Names Veteran Healthcare Executive Dominik Beck President, CEO 2IRIDEX Names Veteran Healthcare Executive Dominik Beck President, CEO 3IRIDEX Names Veteran Healthcare Executive Dominik Beck President, CEO 4Cantel Medical Corp. to Hold Conference Call to Discuss Fourth Quarter and Fiscal 2011 Results 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: