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Social class and changes in mortality from liver cirrhosis over the 20th Century
Date:1/10/2011

en in obese women who drank less than 70 g of alcohol a week (a drink a day).

Multiple risk factors for hepatic cirrhosis: While alcohol is generally considered the most important risk factor for hepatic cirrhosis, there are a number of other factors. One International Scientific Forum on Alcohol Research member stated: "The general impression is that approximately one half of the cases of cirrhosis are related to alcohol consumption; the second important cause is "fatty liver" associated with abdominal obesity, followed by autoimmune diseases, virus hepatitis, and metabolic diseases." Another factor may be the ingestion of medications, such as paracetamol or acetaminophen, which break down to more toxic metabolites. Heavy use of acetaminophen has been shown to relate to cirrhosis.

To conclude, certain medications, coffee consumption, and many other lifestyle factors are associated with hepatic cirrhosis. The actual reasons for the changes over time reported in this paper remain unclear.


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Contact: R Curtis Ellison
ellison@bu.edu
508-333-1256
Boston University Medical Center
Source:Eurekalert

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