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Snake venom studies yield insights for development of therapies for heart disease and cancer
Date:7/29/2010

an assistant professor at the University of Yamanashi.

"We speculate that the interaction between the platelet's CLEC-2 protein and the podoplanin molecule in lymphatic cells plays an essential role in the creation of lymphatic vessels, thereby facilitating tumor growth. If this is the case, a drug that blocks that interaction would prevent the spread of tumors through lymphatic vessels," Inoue said.

By being deemed a "Paper of the Week," the team's work is categorized in the top 1 percent of papers reviewed by the JBC editorial board in terms of significance and overall importance. Other contributors included Guo Ding, Satoshi Nishimura, Kazuya Hokamura, Koji Eto, Hirokazu Kashiwagi, Yoshiaki Tomiyama, Yutaka Yatomi and Kazuo Umemura.


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Contact: Angela Hopp
ahopp@asbmb.org
301-634-7389
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

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