Navigation Links
Snake venom studies yield insights for development of therapies for heart disease and cancer
Date:7/29/2010

BETHESDA, Md., July 29, 2010 Researchers seeking to learn more about stroke by studying how the body responds to toxins in snake venom are this week releasing new findings that they hope will aid in the development of therapies for heart disease and, surprisingly, cancer.

The Japanese team is reporting in a Journal of Biological Chemistry "Paper of the Week" that they are optimistic that inhibiting a protein found on the surface of blood cells known as platelets may combat both irregular blood clotting and the spread of certain cancers throughout the body.

"The finding that platelets not only play a role in blood clotting but also in the development of vessels that allow tumors to flourish was quite unexpected and paves the way for new research on the role or roles of platelets," says Katsue Suzuki-Inoue, the associate professor at the University of Yamanashi who oversaw the 13-person team's work in professor Yukio Ozaki's laboratory.

About platelets, blood clots and stroke

Under normal conditions, platelets are activated to become sticky when blood vessels are injured, and their clumping together (aggregation or clotting) naturally stops bleeding. But, irregular platelet aggregation caused by disease can lead to dangerous clots or even stroke if a clot clogs or bursts in a vessel that carries oxygen and nutrients to the brain.

"When a blood clot, or thrombus, forms during the body's normal repair process, it's doing its job," says Suzuki-Inoue. "But, thrombotic diseases, such as heart attack and stroke, are leading causes of death in developed countries. Understanding and manipulating the underlying chemical reactions could help us save many lives."

But what does this have to do with snake venom? It's sort of a long story.

How venom can prevent or cause clotting

"Snake venom contains a vast number of toxins that target proteins in platelets," says Yonchol Shin, a
'/>"/>

Contact: Angela Hopp
ahopp@asbmb.org
301-634-7389
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Good Bye, Snake Oil! Grab your Orange Juice and Daily Virus Viper™ to Safeguard Against Micro-nutrient Deficiencies
2. CIHR team grant to fund multidisciplinary breast cancer survivorship studies
3. FDA accepts historical controls for epilepsy monotherapy studies
4. Studies explore effects of war on former child soldiers
5. Pediatric clinical studies appear prone to bias, Hopkins review shows
6. Studies of womens attitudes to social egg freezing find reasons differ with age
7. Studies confirm presence, severity of pollution in national parks
8. Vitamin D Deficiency Linked to Diabetes, Metabolic Syndrome in Studies
9. 2 studies: Social factors, super users and urban emergency departments
10. MSU team studies connection between statins, tendon ruptures
11. Quincy Bioscience Launches HOPETrials.com; Research Studies More Accessible For Participants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... 22, 2015 In efforts to offer ... section containing particular muscles stretches has been a large ... of stretches now complete, Chunk Fitness envisions a mid-June ... be filmed and released at a later point in ... here: http://www.chunkfitness.com/stretches . , About the Company: Chunk ...
(Date:5/22/2015)... May 22, 2015 Javon Bea ... be recognized for providing the highest quality emergency care ... health care decision-making,” said Javon R. Bea, President and ... commitment of our employee/partners to care for and respond ... Hospitals do not apply for this award, but are ...
(Date:5/22/2015)... Orlando, FL (PRWEB) May 22, 2015 ... United States and developmental projects in rural India. India ... most popular community projects that continues to help hundreds ... is pleased to sponsor a music concert by famous ... fundraise for the Hindu Society of Central Florida ...
(Date:5/21/2015)... May 21, 2015 Her popular Love Seminar ... Hilton Hotel in San Gabriel on Saturday, May 23rd. ... again from men and women who are unhappy in their ... partner." , "Many singles think that their biggest problem is ... would go from one relationship to another trying to find ...
(Date:5/21/2015)... CA (PRWEB) May 21, 2015 Absolute ... has a highly interactive, state-of-the-art website that is filled ... latest trade show resource information. With its original and ... well as practical. The website shows hundred of pictures ... trade show floor. This is not an exhibit rendering ...
Breaking Medicine News(10 mins):Health News:Mercy Hospital and Trauma Center Receives Women’s Choice Award for Emergency Care - Mercy Health System Javon Bea 2Health News:India Network Visitor Health Insurance Announces Corporate Sponsorship of Anuradha Paudwal Musical in Orlando to Help Fundraise for Hindu Society of Central Florida. 2Health News:Bestselling Author Sheds Light on Why Modern Dating is Hurting People's Chances of Finding a Lasting Relationship 2Health News:New Convention and City Travel Guides Within the Absolute Exhibits’ Website 2
... returned sound to young adults with acoustic neuromas , FRIDAY, ... no longer hear her mother,s voice or the sound of ... earlier, Garrett learned she had neurofibromatosis type 2 (NF2), a ... tumors, acoustic neuromas, damaged the eighth cranial nerve in one ...
... , DETROIT, Sept. 11 United American Healthcare ... its financial results for the fourth fiscal quarter and full year ... close. The Company expects to file its Form 10-K for ... (SEC) on a timely basis in compliance with applicable regulations. ...
... that are now emerging from various clinical trials of ... We expect additional companies to announce their preliminary trial ... that 2009 H1N1 influenza vaccines are well tolerated and ... when administered in a single unadjuvanted 15-microgram dose. We ...
... treatment, researchers say , FRIDAY, Sept. 11 (HealthDay News) ... to develop the most common form of the autoimmune ... it, new research shows. , Lupus, also known ... that often affects the joints, kidneys, blood and nervous ...
... The U.S. Food and Drug Administration today released ... articles can be accessed from the agency,s Web page ... can sign-up for e-mail notices of new consumer updates ... https://service.govdelivery.com/service/subscribe.html?code=USFDA_9 . An RSS feed is also ...
... hard-of-hearing may benefit from electronic assistance, researchers say , ... lips better than people can, new research suggests. , ... the deaf and hard-of-hearing learn to read lips, according ... England. , Researchers compared the accuracy of an automated ...
Cached Medicine News:Health News:Cancer Drug Shrinks Benign Tumors That Steal Hearing 2Health News:Cancer Drug Shrinks Benign Tumors That Steal Hearing 3Health News:United American Healthcare Corporation Announces Release Date for Fiscal 2009 Fourth Quarter and Full Year Results 2Health News:Early results from clinical trials of 2009 H1N1 influenza vaccines in healthy adults 2Health News:Lupus Worse in Blacks, Hispanics Than in Whites, Study Finds 2Health News:FDA Consumer Health Information Updates 2Health News:FDA Consumer Health Information Updates 3Health News:Computers Might Make Learning Lip Reading Easier 2
(Date:5/21/2015)... 21, 2015  Today, eight groups representing ... biologics – Alliance for Patient Access, American ... Rheumatology, Biologics Prescribers Collaborative, Clinical Immunology Society, ... and North American Society for Pediatric Gastroenterology, ... to U.S. Food and Drug Administration (FDA) ...
(Date:5/21/2015)... CITY and SEATTLE , ... leader in the development of robotics, sensors and medical ... as the company,s Chief Financial Officer and head ... of experience in corporate development, business development and finance ... Intellectual Ventures and Pendrell Corporation.  Mr. Woo will be ...
(Date:5/21/2015)... May 21, 2015 Increasing requirements, including ... made flat gaskets indispensable in the chemical and ... internal pressure pose major challenges to their performance. ... of three different materials whose scope covers the ... The white FG-360, based on DIN 28091-3, ...
Breaking Medicine Technology:Physician Groups Urge FDA to Ensure Patient Safety With Greater Transparency in Biosimilar Labeling 2Physician Groups Urge FDA to Ensure Patient Safety With Greater Transparency in Biosimilar Labeling 3Physician Groups Urge FDA to Ensure Patient Safety With Greater Transparency in Biosimilar Labeling 4Sarcos Corp. Announces Preston Woo as CFO and Head of Corporate Development 2Flat gaskets for especially demanding applications in the processing industry 2
... , CLEVELAND, Dec. 16 ... services company focused on global eClinical solutions for the ... version 9.0 eClinical Software. This release advances the ... introduces two new mechanisms for facilitating DATATRAK ONE,s Knowledge(TM) ...
... , , , , ... at,deCODE genetics, Inc. (Nasdaq: DCGN ) publish in the journal Nature the,discovery ... human genome (SNP) with a major impact on susceptibility to type 2,diabetes ... unusual:,if an individual inherits it from their father, the variant increases risk ...
Cached Medicine Technology:DATATRAK's eClinical(TM) 9.0 Software Release furthers Vision of DATATRAK ONE(TM) 2DATATRAK's eClinical(TM) 9.0 Software Release furthers Vision of DATATRAK ONE(TM) 3DATATRAK's eClinical(TM) 9.0 Software Release furthers Vision of DATATRAK ONE(TM) 4deCODE Discovers a Major Risk Factor for Type 2 Diabetes Dependent on Parent of Origin 2deCODE Discovers a Major Risk Factor for Type 2 Diabetes Dependent on Parent of Origin 3deCODE Discovers a Major Risk Factor for Type 2 Diabetes Dependent on Parent of Origin 4
Fine .12mm Tip With 5mm Platform; In Titanium....
45 Degree Angle With 0.3, 12 Teeth with 5mm Tying Platform; In Titanium....
Curved 30mm shaft (in stainless steel); rubber coated for safer use; includes 1.5 meter cable and connectors....
0.3mm tips; 9.5mm from tips to cross action; in Titanium....
Medicine Products: