Navigation Links
Snake spills venomous secrets
Date:11/17/2011

ins Research Center at Texas A&M University.

By exposing neurons cultured in Petri dishes to the various venoms, Bohlen found that the venom from the Texas coral snake targets a receptor protein found on nerve endings all over the body that is sensitive to acid.

Our nerves are very sensitive to acid think lemon juice on a paper cut and for good reason: acid is often an early warning sign for injury.

The researchers found that the snake venom contains two proteins that bind to each other and attach themselves to the human acid receptors much tighter than acid itself does. The proteins also resist being degraded, which may account for their ability to remain on the channels for a long period of time much longer than acid would.

According to Julius, this accounts for the prolonged, intense pain suffered by people bitten by the coral viper.

The toxin provides a tool for looking at the physiological effects of pain receptors, he said. It also suggests that naturally produced components of the human body might be able to mimic the effect of the toxin as part of the normal physiology of modulating pain through these receptors. Having an activator for this channel, like the snake venom, will help researchers search for such natural products and use them in the design of new compounds to block pain.

Moreover the snake venom was found to target a human protein known as the acid-sensing ion channel 1 (ASIC1). For years work in the field has focused on a similar receptor called ASIC3. The work on the Texas coral snake has suggested for the first time that ASIC1 may be a viable target for painkillers.


'/>"/>
Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Antivenom against lethal snake gives hope to developing countries
2. Treat Snakebites With Adrenaline, Study Says
3. What to do if you are bitten by a snake
4. Snake venom studies yield insights for development of therapies for heart disease and cancer
5. Good Bye, Snake Oil! Grab your Orange Juice and Daily Virus Viper™ to Safeguard Against Micro-nutrient Deficiencies
6. New radiation mechanism may ward off cancer, oil spills and terrorism
7. Google Earth typhoid maps reveal secrets of disease outbreaks
8. International team works out secrets of one of worlds most successful patient safety programs
9. Sandia Labs unlocks secrets of plague with stunning new imaging techniques
10. Genome of marine organism reveals hidden secrets
11. Bilingual neurons may reveal the secrets of brain disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Snake spills venomous secrets
(Date:12/20/2014)... Today, Balfleet.com, one of the most outstanding dressmakers ... off on its Mother of the Bride Dresses ... the bride dresses from Balfleet.com feature gorgeous looks and ... takes pride in providing high quality dresses to its ... discounts on our mother of the bride dresses, and ...
(Date:12/19/2014)... (PRWEB) December 20, 2014 Sweetdressy.com ... market, has introduced its newest selection of cheap prom ... are very popular in the world and clients can ... , Meanwhile, these prom dresses feature cool cuts and ... $200 now, targeting the middle-end market. Discount shipping costs ...
(Date:12/19/2014)... CA (PRWEB) December 19, 2014 ... corporation dedicated to developing educational events, tools and ... Rouxbe Cooking School , the world’s leading ... the prescription every human being needs: Culinary Rx. ... plant-based cooking course, Culinary Rx, scheduled for debut ...
(Date:12/19/2014)... Eufaula, Oklahoma, located just 9 miles ... state’s largest lake with more than 600 miles of ... a little more than 3,000 residents, hosted its annual ... 6th of December. , Featuring Santa, Christmas lights and ... on Main Street. Narconon Arrowhead’s parade float participated ...
(Date:12/19/2014)... (PRWEB) December 20, 2014 The Medspa ... new injectable filler from respected cosmetic brand Juvéderm. Voluma ... naturally with age. The Medspa at Hendrick is pleased ... in skin care technology to its clients. , Voluma ... to be FDA-approved to treat the mid-face and cheek ...
Breaking Medicine News(10 mins):Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 2Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 3Health News:The Plantrician Project and the Rouxbe Cooking School Join Forces to Develop Culinary Rx – a Plant-Prescription Course 4Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 2Health News:Narconon Arrowhead Debuts Float at Checotah and Eufaula Christmas Parades 3Health News:Breakthrough New Injectable Dermal Filler Voluma XC Offered by The MedSpa at Hendrick 2
... ... a common technology infrastructure for Policy, Compliance, Risk, SOX, Internal Audits and IT ... ... -- MetricStream, Inc. (“MetricStream”), the market leader in the enterprise-wide Governance, Risk ...
... (NYSE Alternext: ULU), a specialty pharmaceutical company ... and oral care products, today announced it has entered into ... at a price per share of $0.14 pursuant to a ... of approximately $1.5 million. , Investors will also receive warrants ...
... Mass., Nov. 12 Cequent Pharmaceuticals, a pioneer in ... to prevent and treat human disease, has announced that ... application with the U.S. Food and Drug Administration (FDA). ... candidate, targets beta-catenin, a key oncogene implicated in the ...
... Nov. 12 Mary Elizabeth Derig, of Seattle, Washington, ... Edition for her outstanding contributions and achievements in the ... ) , ABOUT MARY ELIZABETH ... an extensive career as a Registered Nurse including work ...
... (NYSE: ABT ) announced today a definitive agreement to ... antibody to Nerve Growth Factor (NGF), expanding the company,s pain ... a novel biologic in Phase I clinical trial development that ... released at sites of tissue damage and inflammation, and plays ...
... ... Mary Alexander will present during Class Action/Mass Torts session discussing tainted food products , ... San Francisco, CA (PRWEB) November 12, ... product law firms in the nation, will take the podium during the 48th Annual Consumer ...
Cached Medicine News:Health News:Amedisys Selects MetricStream for Integrated Enterprise-wide GRC 2Health News:ULURU Inc. to Raise $1.5 Million in Registered Direct Offering 2Health News:Cequent Files its First IND with FDA: CEQ508, a tkRNAi Drug Candidate in Oncology 2Health News:Cequent Files its First IND with FDA: CEQ508, a tkRNAi Drug Candidate in Oncology 3Health News:Cequent Files its First IND with FDA: CEQ508, a tkRNAi Drug Candidate in Oncology 4Health News:Mary Elizabeth Derig Recognized by Strathmore's Who's Who Worldwide Publication 2Health News:Abbott to Acquire Novel Investigational Biologic to Treat Chronic Pain 2Health News:California Consumer Attorney Mary Alexander to Present at 48th Annual COAC Convention 2
(Date:12/19/2014)... has witnessed robust development with the growth pace keeping at ... In 2012, the size of China ... worldwide soaring to 16.3%. It is projected that ... rate by around 20% in the upcoming years and that ... An integrated membrane industrial system has taken shape ...
(Date:12/17/2014)... , Dec. 17, 2014  Strategic Health Services, Inc. ... solutions, today announced a strategic agreement with QualCare, Inc., a ... New Jersey regional marketplace.  This agreement will ... health and wellness solutions QualCare brings to its clients ... surrounding region. QualCare plans cover more ...
(Date:12/17/2014)... December 17, 2014 , ... than a hub of information concerning the biopharmaceutical Group,s national ... A further addition to the recently launched institutional website that ... now been enriched by a new chapter in the fascinating ... A richly detailed and panoramic hub on the world of ...
Breaking Medicine Technology:Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 2Strategic Health Services to collaborate with QualCare on Population Health and Wellness Technology for QualCare Members 3Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3
... NEW YORK, April 27, 2011 ... biopharmaceutical company leveraging its proprietary drug-delivery platforms to develop treatments ... year,s Oncology Nursing Society (ONS) Congress at the Boston Convention ... booth (#652) will be displayed in the Exhibition Hall ...
... Medical Industries, Inc. (OTC: PDMI.PK) announced its success at ... which was held at the Houston Convention Center in ... practice optometrists from many of the most highly regarded ... the annual meeting.  The meeting provided opportunities for participating ...
Cached Medicine Technology:Access Pharmaceuticals to Attend the 36th Annual Oncology Nursing Society Congress 2Access Pharmaceuticals to Attend the 36th Annual Oncology Nursing Society Congress 3Paradigm is Successful at Annual Vision Source Meeting in Houston, Texas 2
... C-terminal cleavage product produced during processing of ... molecule. Although the C-peptide of insulin is ... or extra-renal metabolism and therefore has a ... In addition, C-peptide assays may be analytically ...
... C-peptide of insulin is the C-terminal cleavage ... prohormone to the mature insulin molecule. Although ... it does undergo significant liver or extra-renal ... circulating half-life than insulin [1]. In addition, ...
... 1-2% of circulating testosterone exists as unbound ... is bound to SHBG with high affinity ... to albumin. Both the albumin-bound and free ... effectively inhibits testosterone action. Measurement of the ...
... the first, easy-to-use, non-invasive diagnostic technology ... cardiac dysfunction including acute heart failure, ... cardiac conditions. Designed to seamlessly fit ... enable clinicians caring for cardiac patients ...
Medicine Products: