Navigation Links
Snake spills venomous secrets
Date:11/17/2011

Examining venom from a variety of poisonous snakes, a group of researchers at the University of California, San Francisco has discovered why the bite of one small black, yellow and red serpent called the Texas coral snake can be so painful.

The finding offers insights into chronic and acute pain and provides new research tools that may help pharmaceutical companies design drugs to combat pain.

The venom contains a toxic mixture of chemicals that includes two special proteins that join together, glom tightly onto tiny detectors on human nerve endings and don't let go. These detectors normally sense acid burns, and after the snake bites, the victim's brain receives unrelenting signals of an acid-like burn.

"Bites from this snake are associated with really intense, unremitting pain," said David Julius, PhD, the Morris Herzstein Chair in Molecular Biology & Medicine at UCSF, who led the research. "This work helps to explains why and gives us new tools for examining how our brains perceive pain."

Described this week in the journal Nature, the work teases apart the components of the Texas coral snake's venom and shows how they work in the human body.

While common in Texas and Louisiana, the snake is not considered a major threat to humans. It does not bite people often doing so only defensively when trapped. When it does, however, its neurotoxic venom is so potent that those bitten often have to be hospitalized and given large doses of morphine and other drugs to dampen the intense pain, which can last for weeks.

Venom, Pain, and the Brain

Many of the venoms and toxins in the natural world work by triggering normal mechanisms in the human body designed to detect things like temperature, pressure, and other physical and chemical factors in our environment.

All the information the brain receives about sights, smells, textures and tastes comes through molecular detectors. Found at the en
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Antivenom against lethal snake gives hope to developing countries
2. Treat Snakebites With Adrenaline, Study Says
3. What to do if you are bitten by a snake
4. Snake venom studies yield insights for development of therapies for heart disease and cancer
5. Good Bye, Snake Oil! Grab your Orange Juice and Daily Virus Viper™ to Safeguard Against Micro-nutrient Deficiencies
6. New radiation mechanism may ward off cancer, oil spills and terrorism
7. Google Earth typhoid maps reveal secrets of disease outbreaks
8. International team works out secrets of one of worlds most successful patient safety programs
9. Sandia Labs unlocks secrets of plague with stunning new imaging techniques
10. Genome of marine organism reveals hidden secrets
11. Bilingual neurons may reveal the secrets of brain disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Snake spills venomous secrets
(Date:12/21/2014)... Concept Plus, LLC. a SDB and 8(a) ... VA., today announced it has been recognized by Washington ... ranks the fastest growing government contracting small businesses by calculating ... This is the first year that Concept Plus, LLC., participated ... a 95.92% compound annual growth rate. “For Concept Plus to ...
(Date:12/20/2014)... York, NY (PRWEB) December 20, 2014 ... the healthcare sector have benefited the Massage Services ... the discretionary characteristics of industry products, the anticipated 1.0% ... five-year period has provided consumers with the means to ... that have received a massage in a given year ...
(Date:12/20/2014)... Recently, VogueQueen.com, a leading wedding dress ... Sale Online for 2015. Great discounts are now ... old consumers can get a discount, up to 80% ... website before January 30, 2015. , VogueQueen.com has recently ... a prom dress promotion. Many customers worldwide like VogueQueen’s ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 The aftermath of ... quite a stir, not only in Hollywood, but worldwide. ... 18th , the ripples of that attack are starting a ... jobs at risk. But they are not the only ... could be in for some embarrassing times ahead, agents and ...
(Date:12/20/2014)... Parker & Sons, Inc. a focused and dedicated ... contractor services announces reaching a milestone by providing 40 ... Arizona. Parker and Sons is comprised of a reliable ... customer service the number one priority. The company was ... one service vehicle and has since grown to become ...
Breaking Medicine News(10 mins):Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 3Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 4Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 5Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 2Health News:Parker & Sons Announces Reaching A Milestone By Providing 40 Years Of Dedicated Contractor Services For Homeowners Of Arizona 3
... , , PARK RIDGE, ... sure they,re getting the nutritious breakfast they need for the intense days ... breakfast like eggs can help them stay more focused in class. In ... percent of moms serve hard-cooked eggs for breakfast because of their ease ...
... , , , , ... Four Practicing Physicians Named Runners-Up, also Awarded Cash Prizes ... O,Connell of Boston has been awarded the prestigious J.H. Kanter Prize for his ... homeless people in Boston. , , The inaugural prize, ...
... , , SIGNAL HILL, ... medical technology systems integrator transforming critical care, announced that it ... from the U.S. Army,s Medical Research Material Command for acquisition ... care unit (ICU). , , "Following last ...
... ... will expand the career options of professionals and students in the medical coding field with ... ... company, has announced the launch of a new Inpatient and Outpatient Medical Coding and Billing ...
... ... AllMeds EMR v8.0 has received CCHIT,s 2008 certification for ambulatory electronic ... 100% of CCHIT,s latest functional, interoperability and security requirements. AllMeds ... to ensure that its future solutions will assist physicians and their ...
... , , , ... Inc. ("Astellas") announced today that the U.S. Food and Drug ... ensure the safe and effective use of immunosuppressants (also called ... In their petition, Astellas requested that the FDA take additional ...
Cached Medicine News:Health News:Start the School Year Off Right With an Eggcellent Breakfast 2Health News:Start the School Year Off Right With an Eggcellent Breakfast 3Health News:Dr. James O'Connell Named J.H. Kanter Prize Laureate 2Health News:Dr. James O'Connell Named J.H. Kanter Prize Laureate 3Health News:Integrated Medical Systems Receives $3.25 Million from the U.S. Army for World's First 'Suitcase' Intensive Care Unit 2Health News:Integrated Medical Systems Receives $3.25 Million from the U.S. Army for World's First 'Suitcase' Intensive Care Unit 3Health News:Career Step Announces New Career Training Program for Medical Coding Field 2Health News:AllMeds' EMR Receives CCHIT 2008 Certification Software Complies with 100 Percent of Certification Criteria 2Health News:AllMeds' EMR Receives CCHIT 2008 Certification Software Complies with 100 Percent of Certification Criteria 3Health News:AllMeds' EMR Receives CCHIT 2008 Certification Software Complies with 100 Percent of Certification Criteria 4Health News:Astellas Seeks Rigorous Testing and Safety-Related Labeling for Anti-Rejection Medications 2Health News:Astellas Seeks Rigorous Testing and Safety-Related Labeling for Anti-Rejection Medications 3Health News:Astellas Seeks Rigorous Testing and Safety-Related Labeling for Anti-Rejection Medications 4Health News:Astellas Seeks Rigorous Testing and Safety-Related Labeling for Anti-Rejection Medications 5
(Date:12/17/2014)... , Dec. 17, 2014  Northstar Global Business ... Trust Company (DTC) has made their final decision ... on the Company,s stock effective December 15, 2014, ... stock for depository and book entry transfer services. All ... is now once again fully "DTC Eligible", and ...
(Date:12/17/2014)... LOS ANGELES , Dec. 17, 2014 /PRNewswire/ ... that the US Patent and Trademark Office (USPTO) ... candidate ICT-107, a dendritic cell-based immunotherapeutic vaccine targeting ... glioblastoma. The claims of US Patent No. 8,871,211, ... treating neural cancer by administering a dendritic cell ...
(Date:12/17/2014)... , Dec. 17, 2014 PCCA ... Approved ( http://bit.ly/1382OkS ) program seal for ... community. The program highlights medical practices, materials and ... "autism-community friendly." Children affected by autism ... can be exacerbated by ingredients found in food ...
Breaking Medicine Technology:Northstar announces that the DTC chill on MDIN has been officially lifted 2Northstar announces that the DTC chill on MDIN has been officially lifted 3ImmunoCellular Therapeutics Announces Issuance of Key Patent For ICT-107 Cancer Vaccine 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: