Navigation Links
Smoking may strongly increase long-term risk of eye disease
Date:8/13/2007

Current and past smokers appear to have a higher risk of developing late age-related macular degeneration than those who have never smoked, according to a report in the July issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Age-related macular degeneration (AMD) [a progressive eye disease that affects the central portion of the retina] is the leading cause of blindness in the Western world, according to background information in the article. In addition to smoking, AMD is postulated to share other risk factors with cardiovascular disease, such as elevated cholesterol level and hypertension. Smoking may also interact with AMD gene susceptibility and other environmental risk factors.

Jennifer S. L. Tan, M.B.B.S., B.E., University of Sydney and Westmead Hospital, Sydney, Australia, and colleagues examined 2,454 Australians age 49 and older to study the association between smoking and the 10-year incidence of AMD, as well as the possible links between smoking and other common risk factors. The participants answered a food frequency questionnaire and had retinal photos taken at five-year and 10-year follow-up exams. An interviewer-administered questionnaire assessed participants smoking status. BMI and blood pressure were also measured.

Current smokers were found to be four times more likely to develop age-related macular degeneration and past smokers were three times as likely to have geographic atrophy, an advanced form of the disease, than those who had never smoked. Joint exposure to current smoking and (1) the lowest level of high-density lipoprotein (HDL) [good] cholesterol, (2) the highest total to HDL cholesterol ratio, or (3) low fish consumption was associated with a higher risk of late AMD than the effect of any risk factor alone. However, interactions between smoking and HDL cholesterol level, ratio of total to HDL cholesterol and fish consumption were not statistically significant, the authors write.

In summary, the findings from this large population-based prospective study add evidence to a possible causal relationship between smoking and the long-term risk of late, but not early, AMD, the authors conclude. This supports speculation that AMD is a condition with multiple etiologic factors, and such joint effects contributing to the pathogenesis (origin and development) of AMD could mirror the pathogenesis of cardiovascular disease.


'/>"/>

Contact: Jie Jin Wang, M.Med., Ph.D.
jiejin_wang@wmi.usyd.edu.au
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Vaccine to quit smoking?
2. New hope on the Horizon for People Wishing to Quit Smoking
3. Cancers of Colon & Rectum linked to Cigarette Smoking
4. Smoking a greater risk than HIV? Yes say health experts!!!!
5. Kick Smoking with Nicotine Drink
6. Smoking spreads Cancer
7. ZYBAN, The smoking cessation drug marked for its adverse reactions
8. A boost to quit smoking
9. Quitting smoking stops lung decline
10. Passive smoking affects respiratory system
11. Prescription Drug - Helps People Stop Smoking
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Pixel Film ... Pro X. , "Film editors can give their videos a whole new perspective by ... Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over 30 ...
(Date:6/26/2016)... ... , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a ... fitness app plans to fix the two major problems leading the fitness industry today:, ... type program , They don’t eliminate all the reasons people quit their exercise ...
(Date:6/25/2016)... ... 25, 2016 , ... Experts from the American Institutes for ... Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR ... care planning, healthcare costs and patient and family engagement. , AIR researchers will ...
(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due ... up a new, often overlooked aspect of head lice: the parasite’s ability to live away ... a common occurrence, but a necessary one in the event that lice have simply gotten ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... addition of the "Structural Electronics 2015-2025: Applications, ... In-Mold Electronics, Smart ... Integrated Photovoltaics Structural electronics involves ... as load-bearing, protective structures, replacing dumb structures such ...
(Date:6/24/2016)... According to a new market ... Needles, Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, ... of Purchase (Retail, Non-Retail) - Trends & Global Forecasts ... market for the forecast period of 2016 to 2021. ... by 2021 from USD 1.65 Billion in 2016, growing ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
Breaking Medicine Technology: