Navigation Links
Smoking linked with worse urothelial cancer prognosis in patients, especially women
Date:3/14/2013

Smoking significantly increases individuals' risk of developing serious forms of urothelial carcinoma and a higher likelihood of dying from the disease, particularly for women. That is the conclusion of a recent study published in BJU International. While the biological mechanisms underlying this gender difference are unknown, the findings indicate that clinicians and society in general should focus on smoking prevention and cessation to safeguard against deadly cancers of the bladder, ureters, and renal pelvis, especially in females.

To evaluate the gender-specific effects of smoking habits and cumulative smoking exposure on the health of patients with urothelial carcinoma, investigators led by Shahrokh Shariat, MD, of the Weill Medical College of Cornell University and New York-Presbyterian Hospital in New York City, studied 864 patients (553 men and 311 women) from five international institutions who underwent surgery to treat urothelial carcinoma.

Cancer was more likely to recur in female current smokers than in male current smokers. In heavy long-term smokers, women were 70 percent more likely to experience a cancer recurrence and twice as likely to die from cancer than men. In female patients only, smoking quantity, duration, and cumulative exposure were linked with cancer recurrence and death. For both men and women, those who stopped smoking for more than 10 years saw their risk of dying from cancer revert to that of non-smokers.

"The biological and clinical effect of smoking seems to be different in females than in males. More effort needs to be spent on the science of how normal human biology differs between men and women and how the diagnosis and treatment of urothelial carcinoma differs as a function of gender," said Dr. Shariat. "Also, gender-specific smoking prevention and cessation can have a major health care impact in urothelial carcinoma."


'/>"/>

Contact: Amy Molnar
sciencenewsroom@wiley.com
Wiley
Source:Eurekalert

Page: 1

Related medicine news :

1. Anti-tobacco TV ads help adults stop smoking, study finds
2. Exercise helps smokers to quit smoking, to remain smoke-free and to reduce the risk of death
3. Small neural focus groups predict anti-smoking ad success
4. Some women may be genetically predisposed to smoking-related hot flashes
5. Friends Parents Can Sway Teens Odds for Drinking, Smoking
6. Fewer Young Americans Smoking, Survey Finds
7. Vitamin C improves pulmonary function in newborns of pregnant smoking women
8. Genetic marker may predict smoking quantity in African Americans
9. 5 percent of workers gave up smoking when the anti-tobacco law took effect
10. Vitamin C improves lung function in newborns of pregnant smoking women
11. States Use Only Fraction of Tobacco Revenues to Fight Smoking, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) Board ... Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will ... Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of President ...
(Date:10/13/2017)... ... 2017 , ... PurhealthRX , a leading Health and Nutrition Company, is ... to full spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing ... easily incorporated into liquid products, while reducing costs to end users. , The team ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Lori R. Somekh, ... member of ElderCounsel, a national organization of elder law and special needs planning attorneys. ... and rules. It also provides a forum to network with elder law attorneys nationwide,” ...
(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Oct. 12, 2017   Divoti USA will ... to the standard of the latest FDA requirements, which stipulates new ... Anyone in need of Medical ID jewelry such as Medical ... are engraved in terms of the new FDA requirements ... Divoti offers this dark ...
(Date:10/11/2017)... Oct. 11, 2017  Caris Life Sciences ® , ... the promise of precision medicine, today announced that St. ... Precision Oncology Alliance™ (POA) as its 17 th ... St. Jude Crosson Cancer Institute will help develop standards ... of tumor profiling, making cancer treatment more precise and ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance in ... medical-grade battery-powered display stand specifically designed for endoscopy environments. An innovative ... into a clinical solution to support the improvement of patient outcomes, ... Design ... Solution ...
Breaking Medicine Technology: