Navigation Links
Smoking during pregnancy increases the risk of wheeze and asthma in preschool children
Date:8/16/2012

Maternal smoking during pregnancy is associated with wheeze and asthma inpreschool children, even among children who were not exposed to maternal smoking late inpregnancy or after birth, according to a new study.

"Epidemiological evidence suggests that exposure to maternal smoking during fetal andearly life increases the risk of childhood wheezing and asthma, but earlier studieswere not able to differentiate the effects of prenatal and postnatal exposure," said lead author sa Neuman. MD, of the Institute of Environmental Medicine at the KarolinskaInstitutet in Stockholm, Sweden. "Our study, a large pooled analysis of eight birth cohorts with data on more than 21,000 children, included 735 children who were exposed to maternal smoking only during pregnancy."

"These childrenwere at increased risk for wheeze and asthma at preschool age. Furthermore, the likelihood of developing wheeze and asthma increased in a significant dose-response pattern in relation to maternal cigarette consumption during the first trimester."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

The eight European birth cohorts included in the study included a total of 21,600 children. Exposure information and information on symptoms of wheeze and asthma were derived from parental questionnaires.

In analyses adjusted for sex, parental education, parental asthma, birth weight and siblings, maternal smoking only during pregnancy was associated with increased risks for wheeze (odd ratio 1.39, 95 % CI 1.08-1.77) and asthma (odds ratio 1.65, 1.18-2.31) at age four to six years. Moreover, maternal smoking during the first trimester of pregnancy, but not during the third trimester or the first year following birth, was associated with increased risks for subsequent wheeze and asthma.

"These results indicate that the harmful effects of maternal smoking on the fetal respiratory system begin early in pregnancy, perhaps before the women is even aware that she is pregnant," said Dr. Neuman.

The study has some limitations, including the use of parental questionnaires to obtain exposure and outcome information.

"Our large pooled analysis confirms that maternal smoking during pregnancy, particularly duringthe first trimester, is associated with a greater risk of offspring developing wheeze and asthma when they reach preschool age," concluded Dr. Neuman. "Teens and young women should be encouraged to quit smoking before getting pregnant."


'/>"/>

Contact: Nathaniel Dunford
ndunford@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Related medicine news :

1. Egg Yolks Almost as Bad for Arteries as Smoking: Study
2. Smoking increases, while alcohol consumption may decrease risk of ALS
3. Attitudes toward outdoor smoking ban at moffitt Cancer Center evaluated
4. Reductions in U.S. Teen Smoking Stalled: CDC
5. Seniors with serious illness find smoking, drinking tough habits to break
6. More College Women Smoking Hookahs
7. Smoking Tied to Risk for Hepatitis Return After Liver Transplant
8. Solving the mystery of how cigarette smoking weakens bones
9. Inactivity May Kill as Many Worldwide as Smoking: Report
10. Hookah smoking increasingly common among first-year college women
11. Quitting Smoking Does Mean Weight Gain for Many: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... , ... October 13, 2017 , ... Ellevate Network, the ... business to advocate for action towards gender equality at their inaugural Summit in New ... the globe, and reached a social audience of over 3 million. To watch the ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... has recently contributed a medical article to the newly revamped Cosmetic Town ... article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations (HLI), creator ... tool, and the Cancer Patient Education Network (CPEN), an independent professional organization that ... new strategic alliance. , As CPEN’s strategic partner, HLI will help support ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 5, 2017  In response to the nationwide ... Maxillofacial Surgeons (AAOMS) released prescribing recommendations that urge ... used as a first-line therapy to manage a ... Recognizing the value and importance ... "Opioid Prescribing: Acute and Postoperative Pain Management" stresses ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... 2017  AllianceRx Walgreens Prime, the combined central specialty ... pharmacy benefit manager Prime Therapeutics LLC (Prime), today officially ... the unveiling of new signage at its headquarters in ... at a few other company-owned facilities across the country. ... some of whom will begin to see the AllianceRx ...
Breaking Medicine Technology: