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Smoking and depressive symptoms in adolescent girls are 'red flag' for postmenopausal osteoporosis
Date:4/3/2013

Philadelphia, PA, April 3, 2013 Depression, anxiety, and smoking are associated with lower bone mineral density (BMD) in adults, but these factors have not previously been studied during adolescence, when more than 50% of bone accrual occurs. This longitudinal preliminary study is the first to demonstrate that smoking and depressive symptoms in adolescent girls have a negative impact on adolescent bone accrual and may become a red flag for a future constrained by low bone mass or osteoporosis and higher fracture rates in postmenopausal years. The study is published in the Journal of Adolescent Health, the official journal of the Society for Adolescent Health and Medicine (SAHM).

Osteoporosis is a costly health problem. Although it is primarily evident in postmenopausal women, its roots can be traced to periods of growth, including adolescence. The National Osteoporosis Foundation estimates that ten million Americans already have osteoporosis and an additional 34 million are at risk. In 2005, there were an estimated two million fractures attributed to osteoporosis costing an estimated $19 billion. These numbers are expected to rise to three million fractures and $25.3 billion in costs each year by 2025, presenting a significant public health burden.

Meta-analyses have shown that adult depression is associated with osteoporosis and lower bone mineral density (BMD). Smoking also has a negative impact on bone health, with adult smokers having lower BMD compared to nonsmokers, likely increasing lifetime fracture risk by as much as 31%.

Depression and anxiety increase in adolescence, particularly in girls, and smoking and alcohol use are often initiated at this time. Both depression and substance use often become chronic after adolescence. There is however a dearth of information on whether these factors affect bone accrual in adolescence.

Investigators from the Cincinnati Children's Hospital, University of Cincinnati Coll
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Contact: Eileen Leahy
e.leahy@elsevier.com
732-238-3628
Elsevier Health Sciences
Source:Eurekalert

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