Navigation Links
Smoking Withdrawal Shows Up in Brain Mood Centers
Date:8/3/2011

WEDNESDAY, Aug. 3 (HealthDay News) -- Changes in brain areas that control mood may explain why some heavy smokers become depressed after they quit smoking, which increases their risk of resuming smoking.

That's the finding of Canadian researchers who conducted PET brain scans on 24 nonsmokers, 12 moderate smokers (15 to 24 cigarettes a day) and 12 heavy smokers (25 or more cigarettes a day).

The scans revealed that after quitting smoking, heavy smokers had an elevation of the enzyme monoamine oxidase A (MAO-A) in regions of the brain that regulate mood, such as the prefrontal cortex (24 percent increase) and the anterior cingulate cortex (33 percent increase).

Previous research has linked elevated MAO-A with depression.

Researchers did not find increased levels of MAO-A, which metabolizes mood-enhancing chemicals, in nonsmokers or moderate smokers after they kicked the habit.

The heavy smokers also reported experiencing a depressed mood after they quit smoking.

The study appears in the August issue of the journal Archives of General Psychiatry.

"Understanding the neurobiology of heavy cigarette smoking is important because those who smoke heavily are much more likely to have major depressive disorder and to experience medical complications resulting from cigarette smoking," wrote Ingrid Bacher and colleagues at the Centre for Addiction and Mental Health in Toronto in a journal news release.

They recommended clinical trials to test the effects of MAO-A- inhibiting drugs in heavy smokers immediately after they quit smoking.

More information

The American Cancer Society offers a guide to quitting smoking.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Aug. 1, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. The effects of smoking and alcohol use on risk of upper aero-digestive cancers
2. Licence to smoke: Taking vitamin pills may undermine motivation to reduce smoking
3. Smoking, Diabetes, Obesity May Shrink Your Brain
4. Smoking After Heart Attack Raises Risk of Dying
5. First-ever review finds smoking causes serious birth defects
6. Talking to Teens May Help Them Cut Back on Pot Smoking
7. Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study
8. Varenicline for smoking cessation linked to increased risk of serious harmful cardiac events
9. A Childs Surgery May Prompt Parents to Try to Quit Smoking
10. Smoking During Pregnancy May Predispose Kids to Heart Trouble
11. Smoking may increase risk of prostate cancer recurrence, death
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... and Scientific Sessions in Dallas that it will receive two significant new grants ... grants came as PHA marked its 25th anniversary by recognizing patients, medical professionals ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Dublin ... the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global market ... its applications in various applications. The report deals with ... main industries: pharmaceutical and biotechnology, food and beverage, and ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
Breaking Medicine Technology: