Navigation Links
Smoking Withdrawal Shows Up in Brain Mood Centers
Date:8/3/2011

WEDNESDAY, Aug. 3 (HealthDay News) -- Changes in brain areas that control mood may explain why some heavy smokers become depressed after they quit smoking, which increases their risk of resuming smoking.

That's the finding of Canadian researchers who conducted PET brain scans on 24 nonsmokers, 12 moderate smokers (15 to 24 cigarettes a day) and 12 heavy smokers (25 or more cigarettes a day).

The scans revealed that after quitting smoking, heavy smokers had an elevation of the enzyme monoamine oxidase A (MAO-A) in regions of the brain that regulate mood, such as the prefrontal cortex (24 percent increase) and the anterior cingulate cortex (33 percent increase).

Previous research has linked elevated MAO-A with depression.

Researchers did not find increased levels of MAO-A, which metabolizes mood-enhancing chemicals, in nonsmokers or moderate smokers after they kicked the habit.

The heavy smokers also reported experiencing a depressed mood after they quit smoking.

The study appears in the August issue of the journal Archives of General Psychiatry.

"Understanding the neurobiology of heavy cigarette smoking is important because those who smoke heavily are much more likely to have major depressive disorder and to experience medical complications resulting from cigarette smoking," wrote Ingrid Bacher and colleagues at the Centre for Addiction and Mental Health in Toronto in a journal news release.

They recommended clinical trials to test the effects of MAO-A- inhibiting drugs in heavy smokers immediately after they quit smoking.

More information

The American Cancer Society offers a guide to quitting smoking.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Aug. 1, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. The effects of smoking and alcohol use on risk of upper aero-digestive cancers
2. Licence to smoke: Taking vitamin pills may undermine motivation to reduce smoking
3. Smoking, Diabetes, Obesity May Shrink Your Brain
4. Smoking After Heart Attack Raises Risk of Dying
5. First-ever review finds smoking causes serious birth defects
6. Talking to Teens May Help Them Cut Back on Pot Smoking
7. Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study
8. Varenicline for smoking cessation linked to increased risk of serious harmful cardiac events
9. A Childs Surgery May Prompt Parents to Try to Quit Smoking
10. Smoking During Pregnancy May Predispose Kids to Heart Trouble
11. Smoking may increase risk of prostate cancer recurrence, death
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... ... enough sleep affects much more than energy – it also has mental and physical benefits. ... motor reaction time, which can increase the risk of having a car accident. , ... the NSF to help you sleep better and feel better:, , ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... http://www.wiredlifesolutions.com , “Computers are everywhere and they’re here to stay,” said ... Global Climate Change and Your Health on Voice America sponsored by Nature’s Tears® ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... The ... board members and officers for 2017-2018. The annual board election process has been in ... a volunteer basis. , Thomas C. Dickerson, Ed.D., FACHE, succeeds Jim Hamilton, MHA, CMM, ...
(Date:4/28/2017)... ... April 28, 2017 , ... Children and adolescents who ... experiences than children in the general population. That’s because foster care is designed ... family challenges. While no fault of their own, youth who have experienced trauma ...
(Date:4/28/2017)... Harbor, Md. (PRWEB) , ... April 28, 2017 ... ... Care Association of America (UCAOA) and College of Urgent Care Medicine will host ... 2017 workshops, sessions and speakers will help those in the industry adapt to ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... 2017  AbbVie (NYSE: ABBV), a global biopharmaceutical ... chronic hepatitis C virus (HCV) infected patients with ... compensated cirrhosis (Child-Pugh A) achieved sustained virologic response ... its investigational, pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These ... 12 weeks of G/P treatment without ribavirin. Patients ...
(Date:4/20/2017)... Sweden , April 20, 2017 ... NEVPF) ("NeuroVive") today announced positive preclinical results ... preclinical compound for non-alcoholic steatohepatitis (NASH), in ... NV556 has previously shown ... NASH model. Today, NeuroVive,s scientists present novel ...
(Date:4/19/2017)... , April 19, 2017 Cardiology devices segment ... projected period The Cardiology Devices segment is likely ... US$ 15 Mn in 2018 over 2017. By the end ... market valuation close to US$ 700 Mn, expanding at a ... segment dominated the Asia Pacific reprocessed ...
Breaking Medicine Technology: