Navigation Links
Smoking Withdrawal Shows Up in Brain Mood Centers
Date:8/3/2011

WEDNESDAY, Aug. 3 (HealthDay News) -- Changes in brain areas that control mood may explain why some heavy smokers become depressed after they quit smoking, which increases their risk of resuming smoking.

That's the finding of Canadian researchers who conducted PET brain scans on 24 nonsmokers, 12 moderate smokers (15 to 24 cigarettes a day) and 12 heavy smokers (25 or more cigarettes a day).

The scans revealed that after quitting smoking, heavy smokers had an elevation of the enzyme monoamine oxidase A (MAO-A) in regions of the brain that regulate mood, such as the prefrontal cortex (24 percent increase) and the anterior cingulate cortex (33 percent increase).

Previous research has linked elevated MAO-A with depression.

Researchers did not find increased levels of MAO-A, which metabolizes mood-enhancing chemicals, in nonsmokers or moderate smokers after they kicked the habit.

The heavy smokers also reported experiencing a depressed mood after they quit smoking.

The study appears in the August issue of the journal Archives of General Psychiatry.

"Understanding the neurobiology of heavy cigarette smoking is important because those who smoke heavily are much more likely to have major depressive disorder and to experience medical complications resulting from cigarette smoking," wrote Ingrid Bacher and colleagues at the Centre for Addiction and Mental Health in Toronto in a journal news release.

They recommended clinical trials to test the effects of MAO-A- inhibiting drugs in heavy smokers immediately after they quit smoking.

More information

The American Cancer Society offers a guide to quitting smoking.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Aug. 1, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. The effects of smoking and alcohol use on risk of upper aero-digestive cancers
2. Licence to smoke: Taking vitamin pills may undermine motivation to reduce smoking
3. Smoking, Diabetes, Obesity May Shrink Your Brain
4. Smoking After Heart Attack Raises Risk of Dying
5. First-ever review finds smoking causes serious birth defects
6. Talking to Teens May Help Them Cut Back on Pot Smoking
7. Stop-Smoking Drug Chantix Ups Risk of Heart Problems: Study
8. Varenicline for smoking cessation linked to increased risk of serious harmful cardiac events
9. A Childs Surgery May Prompt Parents to Try to Quit Smoking
10. Smoking During Pregnancy May Predispose Kids to Heart Trouble
11. Smoking may increase risk of prostate cancer recurrence, death
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... More than 20,000 pairs of shoes made their ... to an ambitious venture that conjoined the passions of an NBA star, a Liberty ... Liberty community. These shoes will save lives from the rampant infections transmitted through the ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... a highly specialized asset-light logistics provider of complex transport solutions for mission-critical ... to purchase Unitrans International Corporation, a division of Roadrunner Transportation Systems, Inc. ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... of “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... handheld devices. Through an educational webinar, they will present the line of epMotion ... to learn how easy you can automate everyday pipetting tasks. , Ideal for ...
(Date:8/18/2017)... ... August 18, 2017 , ... Hernandez Insurance ... to communities throughout the greater DC region, is inaugurating a “New Leash On ... local animals and training them to be companions for veterans in need. , ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... 7, 2017 Diplomat Pharmacy, Inc. (NYSE: ... as president, effective Aug. 7, 2017. ... to pursue other interests and will serve as president emeritus ... has served us in multiple leadership roles since he joined ... 2015 and has provided decisive, strategic leadership which continues to ...
(Date:8/4/2017)... CINCINNATI , Aug. 3, 2017  Agragen, ... science company active in the biopharmaceutical, nutraceutical, and ... its development of its lead drug candidates, AGR131.  ... a proinflammatory cytokine from the blood of patients ... psoriasis, and inflammatory bowel disease. ...
(Date:8/2/2017)... Ore. , Aug. 2, 2017  Life Flight Network ... Agreement. The agreement improves patient care and operational efficiency for ... Springfield , Cottage Grove , ... level medical transportation. PeaceHealth and Life Flight Network work collaboratively ... available during transport, or when a time sensitive emergency exists. ...
Breaking Medicine Technology: