Navigation Links
Smoking Ups Colon Cancer Risk
Date:12/16/2008

Most significant effect was seen after 30 years of smoking, researchers say,,,,

TUESDAY, Dec. 16 (HealthDay News) -- Adding to the long list of cancers caused by smoking, Italian researchers report that the risk of getting colorectal cancer is higher in smokers, as is the risk of dying from that disease.

Smoking increases the risk of developing colorectal cancer by about 18 percent and the risk of dying from the malignancy by about 25 percent, according to the study, which was published in the Dec. 17 issue of the Journal of the American Medical Association.

"Smoking is significantly associated with colorectal cancer incidence and mortality," said the study's lead author, Edoardo Botteri, a biostatistician in the division of epidemiology and biostatistics at the European Institute of Oncology in Milan, Italy.

"People should be aware that smoking increases the risk of cancer not only in organs where there is direct contact with tobacco-related carcinogens, such as lung, oropharynx, larynx and upper digestive tract, but also in organs where exposure to tobacco degradation products is indirect, such as the pancreas, kidney, bladder, cervix, colon and rectum," explained Botteri.

Tobacco is responsible for about 100 million deaths during the past century and more than 5 million deaths a year, according to background information in the study. Yet, the study pointed out, there are still more than 1 billion smokers worldwide. Eighty percent of lung cancers are directly attributable to smoking, reports the study.

However, the connection to colorectal cancer isn't as conclusive.

To assess whether or not there is, in fact, a link, Botteri and his colleagues analyzed data from 106 observational studies that varied from small trials containing just several hundred participants to very large trials with more than 1 million participants.

When the researchers looked at the pooled risk, they found that smoking was associated with an 18 percent rise in the odds of getting colorectal cancer.

And, Botteri added, "There was an increase in risk with increasing number of cigarettes per day and pack-years -- the number of packs of cigarettes smoked per day multiplied by years of consumption."

The increased risk began after about 10 years of smoking and increased until it reached statistical significance after 30 years.

"That doesn't mean that there is no increased risk for people who smoked less than 30 years," noted Botteri, "It just means that there is strong evidence that exposure of 30 years or more increases the risk of colorectal cancer."

The researchers also found that smoking increased the risk of death from colorectal cancer by 25 percent.

Dr. Michael Thun, vice president emeritus of epidemiology and surveillance research at the American Cancer Society, said the study will be of most interest to researchers that study colon cancer, and he doesn't believe the findings will change screening recommendations.

Another message remains the same, he added: "With or without a relationship to colorectal cancer, the message is to avoid all forms of tobacco."

Botteri, however, believes that doctors should be "more vigilant" about making sure that smokers are compliant with current screening recommendations, and that perhaps, the initial screening age should be lowered for smokers.

More information

Learn more about the risk factors for colorectal cancer from the American Cancer Society.



SOURCES: Edoardo Botteri, M.Sc., biostatistician, European Institute of Oncology, Milan, Italy; Michael Thun, M.D., vice president emeritus, epidemiology and surveillance research, American Cancer Society, Atlanta; Dec. 17, 2008, Journal of the American Medical Association


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Quitting Smoking Can Be a Parents Best New Years Resolution
2. New Survey Shows Continued Progress in Reducing Youth Smoking; Congress, States Can Accelerate Declines by Implementing Proven Solutions
3. December 2008 Mayo Clinic Womens HealthSource Highlights Happiness, Dementia and Smoking
4. New Research May Encourage Smokers to Jump-Start Their New Years Resolution to Quit Smoking
5. New Tobacco Research Finds Minnesotas Latino Population Smoking Significantly Less than General Population
6. Surprising Results on Smoking Research Hispanic Versus White Female Smokers
7. Newborns exposed to maternal smoking more irritable, difficult to soothe
8. High levels of prenatal smoking exposure affect sleep patterns in preterm neonates
9. Report Shows Progress in Fight Against Cancer, but Congress, States Must Step Up Efforts to Reduce Smoking, Lung Cancer
10. Mother of Five Wins $5,000 in Minnesota Quit-Smoking Contest
11. Smoking, teens and their parents: New research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking Ups Colon Cancer Risk
(Date:4/21/2017)... ... 21, 2017 , ... Contrary to popular perception, a new ... at noteworthy rates. Between 2002 and 2014, Salas-Wright and his colleagues found a ... the United States. The study, Trends in Fighting and Violence Among Adolescents ...
(Date:4/21/2017)... , ... April 21, 2017 , ... Brady ... that its B-595 and B-7569 vinyl label materials received certification ... warning labels are tested to remain intact and legible, for use on chemical drums ...
(Date:4/21/2017)... Colo. (PRWEB) , ... April 21, 2017 , ... The ... the Flex House, the next project in the company’s esteemed VISION House demonstration project ... homeowners use exactly the amount of resources they need to live affordably and abundantly ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... The Hong ... the first 3D printing facility among higher education institutions in Hong Kong to support ... in terms of the range and quantity of facilities in Hong Kong. , ...
(Date:4/21/2017)... British Columbia (PRWEB) , ... April 21, 2017 , ... ... at treating people who wish to overcome their mental health struggles. The Alive team ... Director Vic LeBouthillier says: “Our approach in dealing with a mental health struggle is ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017  AbbVie (NYSE: ABBV), ... percent (n=145/146) of chronic hepatitis C virus (HCV) ... or 6 and compensated cirrhosis (Child-Pugh A) achieved ... 12 ) with its investigational, pan-genotypic regimen of ... were seen following 12 weeks of G/P treatment ...
(Date:4/20/2017)... DUBLIN , April 20, 2017 ... "Latin America Pharmaceutical Contract Manufacturing Services Market Analysis By Service ... And Segment Forecasts, 2014 - 2025" report to their ... The Latin ... USD 21.0 billion by 2025 Low drug registration ...
(Date:4/19/2017)... VIEW, Calif. , April 19, 2017  IRIDEX ... it will release financial results for the first quarter ... 3, 2017.  The Company,s management team will host a ... 5:30 p.m. ET. Investors interested in listening ... (844) 707-0665 for domestic callers or (703) 326-3030 for ...
Breaking Medicine Technology: