Navigation Links
Smoking Ups Colon Cancer Risk

Most significant effect was seen after 30 years of smoking, researchers say,,,,

TUESDAY, Dec. 16 (HealthDay News) -- Adding to the long list of cancers caused by smoking, Italian researchers report that the risk of getting colorectal cancer is higher in smokers, as is the risk of dying from that disease.

Smoking increases the risk of developing colorectal cancer by about 18 percent and the risk of dying from the malignancy by about 25 percent, according to the study, which was published in the Dec. 17 issue of the Journal of the American Medical Association.

"Smoking is significantly associated with colorectal cancer incidence and mortality," said the study's lead author, Edoardo Botteri, a biostatistician in the division of epidemiology and biostatistics at the European Institute of Oncology in Milan, Italy.

"People should be aware that smoking increases the risk of cancer not only in organs where there is direct contact with tobacco-related carcinogens, such as lung, oropharynx, larynx and upper digestive tract, but also in organs where exposure to tobacco degradation products is indirect, such as the pancreas, kidney, bladder, cervix, colon and rectum," explained Botteri.

Tobacco is responsible for about 100 million deaths during the past century and more than 5 million deaths a year, according to background information in the study. Yet, the study pointed out, there are still more than 1 billion smokers worldwide. Eighty percent of lung cancers are directly attributable to smoking, reports the study.

However, the connection to colorectal cancer isn't as conclusive.

To assess whether or not there is, in fact, a link, Botteri and his colleagues analyzed data from 106 observational studies that varied from small trials containing just several hundred participants to very large trials with more than 1 million participants.

When the researchers looked at the pooled risk, they found that smoking was associated with an 18 percent rise in the odds of getting colorectal cancer.

And, Botteri added, "There was an increase in risk with increasing number of cigarettes per day and pack-years -- the number of packs of cigarettes smoked per day multiplied by years of consumption."

The increased risk began after about 10 years of smoking and increased until it reached statistical significance after 30 years.

"That doesn't mean that there is no increased risk for people who smoked less than 30 years," noted Botteri, "It just means that there is strong evidence that exposure of 30 years or more increases the risk of colorectal cancer."

The researchers also found that smoking increased the risk of death from colorectal cancer by 25 percent.

Dr. Michael Thun, vice president emeritus of epidemiology and surveillance research at the American Cancer Society, said the study will be of most interest to researchers that study colon cancer, and he doesn't believe the findings will change screening recommendations.

Another message remains the same, he added: "With or without a relationship to colorectal cancer, the message is to avoid all forms of tobacco."

Botteri, however, believes that doctors should be "more vigilant" about making sure that smokers are compliant with current screening recommendations, and that perhaps, the initial screening age should be lowered for smokers.

More information

Learn more about the risk factors for colorectal cancer from the American Cancer Society.

SOURCES: Edoardo Botteri, M.Sc., biostatistician, European Institute of Oncology, Milan, Italy; Michael Thun, M.D., vice president emeritus, epidemiology and surveillance research, American Cancer Society, Atlanta; Dec. 17, 2008, Journal of the American Medical Association

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Quitting Smoking Can Be a Parents Best New Years Resolution
2. New Survey Shows Continued Progress in Reducing Youth Smoking; Congress, States Can Accelerate Declines by Implementing Proven Solutions
3. December 2008 Mayo Clinic Womens HealthSource Highlights Happiness, Dementia and Smoking
4. New Research May Encourage Smokers to Jump-Start Their New Years Resolution to Quit Smoking
5. New Tobacco Research Finds Minnesotas Latino Population Smoking Significantly Less than General Population
6. Surprising Results on Smoking Research Hispanic Versus White Female Smokers
7. Newborns exposed to maternal smoking more irritable, difficult to soothe
8. High levels of prenatal smoking exposure affect sleep patterns in preterm neonates
9. Report Shows Progress in Fight Against Cancer, but Congress, States Must Step Up Efforts to Reduce Smoking, Lung Cancer
10. Mother of Five Wins $5,000 in Minnesota Quit-Smoking Contest
11. Smoking, teens and their parents: New research
Post Your Comments:
Related Image:
Smoking Ups Colon Cancer Risk
(Date:11/29/2015)... ... November 29, 2015 , ... Effective immediately, every single IguanaMed scrub style ... Black Friday Target is offering a “Buy One Scrub Set, Get the 2nd Scrub ... to purchase IguanaMed at a discounted price. , IguanaMed’s mission is to ...
(Date:11/28/2015)... ... ... Safe storage for contraceptive devices may not always be easy to find. ... the other from Bradley Beach, New Jersey, there is an easy solution to the ... replace NuvaRings more often than necessary. As such, it affords peace of mind and ...
(Date:11/28/2015)... CA (PRWEB) , ... November 28, 2015 , ... Pixel ... fully customizable media panels to choose from, the possibilities are endless. Users have full ... more. With the ProPanel: Pulse masking effects, users are sure to get heads to ...
(Date:11/27/2015)... , ... November 27, 2015 , ... According to an ... by the University of Toronto and the University of British Columbia suggested that laws ... head injuries. The article explains that part of the reason for the controversial conclusion ...
(Date:11/27/2015)... ... ... A team of Swiss doctors has released a report on mesothelioma relapse ... the findings on the website. Click here to read the details now. ... who were treated with chemotherapy followed by EPP surgery. Among the 106 patients who ...
Breaking Medicine News(10 mins):
(Date:11/29/2015)... , Nov. 29, 2015  At this year,s ... to experience the most complete mobile C-arm portfolio with ... is Ziehm Vision RFD 3D, the world,s only 3D ... edge length per scan volume. In addition, Ziehm Imaging ... motorized mobile C-arm in four axes which is ideally ...
(Date:11/29/2015)... CORALVILLE, Iowa , Nov. 29, 2015 /PRNewswire/ ... in ultrasound guidance technology at the Radiological Society ... conference in Chicago November ... guidance system is designed to offer customers unrivaled ... outcomes. --> ...
(Date:11/27/2015)... 2015 Une nouvelle approche ... Bremachlorin contre le cancer avancé.    ... l,immunothérapie au traitement photodynamique au Bremachlorin contre le ... Une nouvelle approche consistant à combiner l,immunothérapie au ...    Clinical Cancer Research . ...
Breaking Medicine Technology: