Navigation Links
Smoking May Up Risk of ALS
Date:2/14/2011

MONDAY, Feb. 14 (HealthDay News) -- Smoking may increase the risk of the fatal muscle-wasting disease amyotrophic lateral sclerosis (ALS), researchers warn.

Each year in the United States, more than 5,500 people are diagnosed with ALS, also known as Lou Gehrig's disease. There is no cure for the disease and treatments are very limited.

In this study, researchers analyzed data from five long-term studies that involved a total of more than 1.1 million people, including 832 with ALS. Follow-up in the studies ranged from seven to 28 years.

Compared to nonsmokers, the risk of developing ALS was 42 percent higher in current smokers and 44 percent higher in former smokers. The researchers also found that the risk of developing ALS increased by 10 percent for each additional 10 cigarettes smoked per day and by nine percent for each 10 years of smoking.

The researchers also found that the younger a person was when they started smoking, the greater their risk of developing ALS.

"Several possible mechanisms by which cigarette smoking might influence the risk of ALS have been suggested, including direct neuronal damage from nitric oxide or other components of cigarette smoke [such as residues of pesticides used in tobacco cultivation] or from oxidative stress," wrote Dr. Hao Wang, of the Harvard School of Public Health, and colleagues.

"Chemicals that are present in cigarette smoke generate free radicals and products of lipid peroxydation, and smokers have a higher turnover of the major antioxidant vitamin C. Exposure to formaldehyde, a byproduct of the combustion product of tobacco smoking, was reported in 2008 to be associated with an increased risk of ALS," Wang said.

The researchers concluded: "Better understanding of the relation between smoking and ALS may further the discovery of other risk factors and help elucidate the nature of the disease."

The study is puiblished in the February issue of the Archives of Neurology.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about ALS.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Feb. 14, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. First Lady Says President Obama Has Quit Smoking
2. Brain scans predict likely success when it comes to quitting smoking
3. Resolved to quit smoking?
4. Odds of Quitting Smoking May Be Clear on Scans
5. Smoking, Obesity Slowing U.S. Life Expectancy Gains: Report
6. Smoking may be associated with increased risk of breast cancer
7. Heavy Smoking Linked to Small Increase in Breast Cancer Risk
8. Smoking Scenes in Movies Light Up Smokers Brains
9. Smoking Damages DNA Within Minutes, Research Shows
10. Europe reins in the smoking habit
11. Studies Decipher How Anti-Smoking Drugs Work
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking May Up Risk of ALS
(Date:4/30/2016)... ... April 30, 2016 , ... ... questioned the use of the HyProCure sinus tarsi implant. ( http://www.cbc.ca/news/canada/ottawa/banned-quebec-dentist-pierre-dupont-working-as-chiropodist-in-ottawa-1.3515494 ) ... is a minimally invasive procedure performed, when indicated, to correct the partial ...
(Date:4/29/2016)... ... ... In an article published April 16th on the New York ... injections, which she underwent in order to feel more at home at this year’s ... article explains that Ms. Mirmelli’s situation is not unique; many plastic surgeons say they’ve ...
(Date:4/29/2016)... ... April 29, 2016 , ... On Tuesday, April 26, ... the Southeast, celebrated the signature of Gov. Nathan Deal on SB 258, the “Rural ... (R - Cumming), offers a 70% tax credit to individuals and corporations which donate ...
(Date:4/29/2016)... ... , ... Coast Dental Fort Stewart is celebrating its grand opening with an ... Furniture Mall at 112 Vilseck Road in Fort Stewart. There will be refreshments, giveaways, ... have the opportunity to meet general dentists Thomas Richards, DDS, and Josh Faulk, DMD, ...
(Date:4/29/2016)... ... April 29, 2016 , ... World Patent ... Gyrociser, an exercise invention which aids in proper muscle development. , "The Gym ... and Creative Director of World Patent Marketing. "Globalization has threatened the future growth ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... JERUSALEM , April 28, 2016 ... ), a clinical-stage pharmaceutical company focused on the development of ... participate in the upcoming PIONEERS 2016 conference, presented by ... 5, 2016 in New York . ... overview at the conference. Presentation Details:   ...
(Date:4/28/2016)... TapImmune,Inc. (TPIV), a clinical-stage immune-oncology company ... and vaccines for the treatment of cancer & metastatic disease, ... Growth Capital Expo to be held on May 3 ... in Las Vegas, Nevada.  The Company presentation will be ... by Dr. John N. Bonfiglio a TapImmune Board ...
(Date:4/27/2016)... 2016 Im ... Zürich gab Strekin AG den Start einer ... Erhaltung des Resthörvermögens von Patienten, denen ein ... umfassende Phase-II-Doppelblindstudie mit Placebo-Kontrollgruppe werden momentan Patienten ... während der Operation direkt ins Mittelohr verabreicht. ...
Breaking Medicine Technology: