Navigation Links
Smoking May Up Risk of ALS
Date:2/14/2011

MONDAY, Feb. 14 (HealthDay News) -- Smoking may increase the risk of the fatal muscle-wasting disease amyotrophic lateral sclerosis (ALS), researchers warn.

Each year in the United States, more than 5,500 people are diagnosed with ALS, also known as Lou Gehrig's disease. There is no cure for the disease and treatments are very limited.

In this study, researchers analyzed data from five long-term studies that involved a total of more than 1.1 million people, including 832 with ALS. Follow-up in the studies ranged from seven to 28 years.

Compared to nonsmokers, the risk of developing ALS was 42 percent higher in current smokers and 44 percent higher in former smokers. The researchers also found that the risk of developing ALS increased by 10 percent for each additional 10 cigarettes smoked per day and by nine percent for each 10 years of smoking.

The researchers also found that the younger a person was when they started smoking, the greater their risk of developing ALS.

"Several possible mechanisms by which cigarette smoking might influence the risk of ALS have been suggested, including direct neuronal damage from nitric oxide or other components of cigarette smoke [such as residues of pesticides used in tobacco cultivation] or from oxidative stress," wrote Dr. Hao Wang, of the Harvard School of Public Health, and colleagues.

"Chemicals that are present in cigarette smoke generate free radicals and products of lipid peroxydation, and smokers have a higher turnover of the major antioxidant vitamin C. Exposure to formaldehyde, a byproduct of the combustion product of tobacco smoking, was reported in 2008 to be associated with an increased risk of ALS," Wang said.

The researchers concluded: "Better understanding of the relation between smoking and ALS may further the discovery of other risk factors and help elucidate the nature of the disease."

The study is puiblished in the February issue of the Archives of Neurology.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about ALS.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Feb. 14, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. First Lady Says President Obama Has Quit Smoking
2. Brain scans predict likely success when it comes to quitting smoking
3. Resolved to quit smoking?
4. Odds of Quitting Smoking May Be Clear on Scans
5. Smoking, Obesity Slowing U.S. Life Expectancy Gains: Report
6. Smoking may be associated with increased risk of breast cancer
7. Heavy Smoking Linked to Small Increase in Breast Cancer Risk
8. Smoking Scenes in Movies Light Up Smokers Brains
9. Smoking Damages DNA Within Minutes, Research Shows
10. Europe reins in the smoking habit
11. Studies Decipher How Anti-Smoking Drugs Work
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking May Up Risk of ALS
(Date:10/13/2017)... ... 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud ... and unique items from across the nation, this holiday-themed event will raise funds and ... the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids ... Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, ... run is geared towards children of all ages; it is a non-competitive, non-timed event, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor ... on sciatica in a new episode of "Success Files," which is an award-winning ... innovation and investigates each subject in-depth with passion and integrity. , Sciatica occurs ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... FRISCO, Texas , Oct. 11, 2017 /PRNewswire/ ... healthcare services, has amplified its effort during National ... patients about hereditary cancer risks. ... Journal of Clinical Oncology calculated that more than ... to have inherited mutations in BRCA1 or BRCA2 and ...
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/2/2017)... -- Eli Lilly and Company (NYSE: LLY ) ... of 2017 on Tuesday, October 24, 2017. Lilly will ... the investment community and media to further detail the ... begin at 9 a.m. Eastern time. Investors, media and ... the conference call through a link that will be ...
Breaking Medicine Technology: