Navigation Links
Smoking May Harm the Egg, Embryo
Date:11/17/2008

Study in mice points to real damage, scientists say

MONDAY, Nov. 17 (HealthDay News) -- In research that might have implications for human reproduction, U.S. and Chinese scientists have found that cigarette smoke damages mouse eggs and embryos.

The study was designed to examine whether cigarette smoke causes oxidative stress, cell death and dysfunction, and the shortening of telomeres (DNA at the ends of chromosomes that protect them from degradation). Two groups of female mice were exposed to cigarette smoke or cigarette smoke condensate for four weeks and compared to a control group of mice.

The mice exposed to cigarette smoke or the condensate were more likely than the unexposed mice to show increased fragmentation and delayed fertilization, resulting in impaired embryo development, the study found.

The fragmented eggs also showed oxidative stress, and embryos from mice exposed to cigarette smoke or condensate for four weeks before fertilization were more likely to contain dead cells and altered expression of the protein Oct4, which plays an important role in the formation of viable blastocysts (a stage of embryonic development).

The association between cigarette smoke or condensate and embryo development was dependent on the length of exposure, the team noted. But even embryos exposed to smoke for as little as four days showed reduced telomere length in cells and decreased blastocyst development, suggesting that embryos may be more sensitive to smoke-induced oxidative stress than eggs, the researchers said.

The study was published in the November issue of the journal Fertility and Sterility.

"Here is even more evidence demonstrating the dreadful effects smoking has on reproductive tissues and function. While there are some data implying that the effects may not be permanent, every woman planning to become pregnant would be wise to quit smoking or, better yet, never start," Dr. William Gibbons, president-elect of the American Society for Reproductive Medicine, said in a society news release.

More information

The American Lung Association has more about smoking and pregnancy.



-- Robert Preidt



SOURCE: American Society for Reproductive Medicine, news release, Nov. 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. U.S. Wont Meet 2010 No-Smoking Goals
2. States Should Fund Quit-Smoking Treatments: Experts
3. UCLA study reveals smokings effect on nurses health, death rates
4. CDC Reports Drop in Adult Smoking, But Death Toll and Health Costs Are Still Growing; Congress, States Should Implement Proven Solutions
5. Quitting Smoking Saves Lives and Money: New American Lung Association Report Finds Most States Failing to Adequately Protect Residents and Their Bottom Line
6. Study: Smoking Ban Would Help Reduce Heart Attack Admissions
7. New Stop Smoking Aid Offers Unique Teeth Whitening Benefit
8. Current Economic Situation Prompts Increased Smoking, Delay in Quit Attempts, Middle and Low-Income Americans Hit Hardest
9. Smoking Coupled With Obesity Raises Death Risk
10. Study finds racial disparities increasing for cancers unrelated to smoking
11. Moms Smoking Linked to Increased Risk of Birth Defects
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking May Harm the Egg, Embryo
(Date:1/24/2017)... , ... January 24, 2017 , ... “Speaking With God’s ... With God’s Voice” is the creation of published author, Louis A. Miraglia, a born-again ... how best to deliver God’s great, impactful Word. , “There is little doubt ...
(Date:1/24/2017)... ... January 24, 2017 , ... “The Octagon of Spiritual Balances”: a ... Balances” is the creation of published author, Pastor Bernard J. Weathers, pastor of Word ... bachelor degree in religious education and a master degree in theology. , ““The Octagon ...
(Date:1/24/2017)... ... 2017 , ... OSF Ventures, the corporate investment arm of ... headquartered in Silicon Valley that connects startups to corporations and invests in more ... agreement to be a corporate sponsor of Plug and Play’s program for Health ...
(Date:1/24/2017)... (PRWEB) , ... January 23, 2017 , ... ... men who support them, Dr. Carol Francis, Psychologist in the South Bay ... pay, humane respectful governing for all people and by all people shines as ...
(Date:1/23/2017)... Alto, CA (PRWEB) , ... ... ... a provider of translation and localization services for life science companies, has ... and inspection organization, TÜV SÜD America. ISO 17100 is the globally recognized ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... Jan. 23, 2017  Allergan plc, (NYSE: AGN ... support of the International Headache Academy (IHA). Designed to inspire ... research scientists, IHA offers a three-day, intensive overview on research ... has been the sole sponsor since the inception of IHA ... iHEAD in Europe in 2014. ...
(Date:1/23/2017)... , Jan. 23, 2017  Using Astute Medical,s ... high risk for acute kidney injury (AKI) after ... globally-recognized care guidelines significantly improved outcomes ... AKI more than 33 percent, according to a ... journal Intensive Care Medicine. ...
(Date:1/23/2017)... YORK , January 23, 2017 ... Catalyst Pharmaceuticals Inc. (NASDAQ: CPRX ), Sophiris Bio ... MNTA ), and Agile Therapeutics Inc. (NASDAQ: ... sector which turned somewhat lower in late trade on Friday, ... Index dropping about 0.3%, while shares of health care companies ...
Breaking Medicine Technology: