Navigation Links
Smoking May Harm the Egg, Embryo
Date:11/17/2008

Study in mice points to real damage, scientists say

MONDAY, Nov. 17 (HealthDay News) -- In research that might have implications for human reproduction, U.S. and Chinese scientists have found that cigarette smoke damages mouse eggs and embryos.

The study was designed to examine whether cigarette smoke causes oxidative stress, cell death and dysfunction, and the shortening of telomeres (DNA at the ends of chromosomes that protect them from degradation). Two groups of female mice were exposed to cigarette smoke or cigarette smoke condensate for four weeks and compared to a control group of mice.

The mice exposed to cigarette smoke or the condensate were more likely than the unexposed mice to show increased fragmentation and delayed fertilization, resulting in impaired embryo development, the study found.

The fragmented eggs also showed oxidative stress, and embryos from mice exposed to cigarette smoke or condensate for four weeks before fertilization were more likely to contain dead cells and altered expression of the protein Oct4, which plays an important role in the formation of viable blastocysts (a stage of embryonic development).

The association between cigarette smoke or condensate and embryo development was dependent on the length of exposure, the team noted. But even embryos exposed to smoke for as little as four days showed reduced telomere length in cells and decreased blastocyst development, suggesting that embryos may be more sensitive to smoke-induced oxidative stress than eggs, the researchers said.

The study was published in the November issue of the journal Fertility and Sterility.

"Here is even more evidence demonstrating the dreadful effects smoking has on reproductive tissues and function. While there are some data implying that the effects may not be permanent, every woman planning to become pregnant would be wise to quit smoking or, better yet, never start," Dr. William Gibbons, president-elect of the American Society for Reproductive Medicine, said in a society news release.

More information

The American Lung Association has more about smoking and pregnancy.



-- Robert Preidt



SOURCE: American Society for Reproductive Medicine, news release, Nov. 17, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. U.S. Wont Meet 2010 No-Smoking Goals
2. States Should Fund Quit-Smoking Treatments: Experts
3. UCLA study reveals smokings effect on nurses health, death rates
4. CDC Reports Drop in Adult Smoking, But Death Toll and Health Costs Are Still Growing; Congress, States Should Implement Proven Solutions
5. Quitting Smoking Saves Lives and Money: New American Lung Association Report Finds Most States Failing to Adequately Protect Residents and Their Bottom Line
6. Study: Smoking Ban Would Help Reduce Heart Attack Admissions
7. New Stop Smoking Aid Offers Unique Teeth Whitening Benefit
8. Current Economic Situation Prompts Increased Smoking, Delay in Quit Attempts, Middle and Low-Income Americans Hit Hardest
9. Smoking Coupled With Obesity Raises Death Risk
10. Study finds racial disparities increasing for cancers unrelated to smoking
11. Moms Smoking Linked to Increased Risk of Birth Defects
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking May Harm the Egg, Embryo
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Yisrayl Hawkins, ... week that explains one of the most popular and least understood books in the ... cryptic and puzzling descriptions that have baffled scholars for centuries. Many have tossed it ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian ... On The Brink” is the creation of published author, William Nowers. Captain Nowers ... a WWII veteran, he spent thirty years in the Navy. Following his career ...
(Date:10/12/2017)... ... 12, 2017 , ... CitiDent and San Francisco dentists, Dr. ... Oventus O2Vent technology. As many as 18 million Americans are estimated to suffer ... Oral appliances can offer significant relief to about 75 percent of people with ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)...   ZirMed Inc ., a recognized leader in cloud-based ... has been ranked #1 by its users for the seventh ... User Survey. ZirMed was recognized as the top-ranked end-to-end revenue ... centers over 200 beds and holds one of the longest ... history. ...
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
(Date:9/12/2017)... Sept. 12, 2017   EcoVadis , the leading platform for environmental, ... first annual edition of its Global CSR Risk and Performance Index. The ... EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points across ... ... ...
Breaking Medicine Technology: