Navigation Links
Smoking-Low Birth Weight Link Explained in Part
Date:2/2/2009

Tobacco use narrows blood vessels to fetus, study finds

MONDAY, Feb. 2 (HealthDay News) -- A mechanism linking smoking during pregnancy to low birth weight has been identified by Danish researchers.

They found that smoking during pregnancy lowers production of an enzyme called endothelial nitric oxide synthase (eNOS), which regulates blood vessel dilation. Reduced production of eNOS causes narrowing of blood vessels and less blood flow to the fetus, resulting in lower birth weight, shorter length and smaller head circumference.

But the researchers also found that if women quit smoking early in pregnancy, eNOS levels return to normal, and infants are born at normal birth weight. The findings were published in the Feb. 2 online issue of Circulation.

"This study in one of the first to show a biochemical measurement of what is going on to cause the lower birth weight," said study author Malene Rohr Andersen, project manager of the Department of Clinical Biochemistry at Gentofte University Hospital.

"We have known for 50 years that infants born to mothers who smoke during pregnancy have lower birth weights. But this study provides a possible explanation of why there is restricted blood flow to the fetus. Reduced production of the vasodilator nitric oxide may lower the blood flow to the fetus," Andersen said in an American Heart Association news release.

The researchers looked at 266 healthy pregnancies of 182 nonsmokers, 43 smokers, and 41 women who stopped smoking at about six weeks into their pregnancy. The more cigarettes smoked per day, the lower the levels of eNOS concentration and activity.

The average difference in the newborn weight of infants born to nonsmokers and smokers was about 350 grams. Differences in eNOS activity accounted for about 25 percent of the birth weight reduction among infants born to smokers.

"Women who smoke should stop smoking if they plan to become pregnant, or at the very least should stop smoking as soon as they find out they are pregnant," Andersen said. "Women should also not start smoking again once they have delivered. Some women stop smoking during pregnancy, only to start up again after the baby is delivered, and the child is then exposed to environmental smoke, which also affects vascular function."

More information

The American Lung Association has more about smoking and pregnancy.



-- Robert Preidt



SOURCE: American Heart Association, news release, Feb. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Another Reason Not to Smoke While Pregnant: Birth Defects
2. More than two-thirds of sexually active NYC youth use condoms, but other forms of birth control lag
3. Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration
4. Steroids Seem Safe for Babies at Risk of Early Birth
5. Many U.S. Women Unaware of Birth Defect Risks
6. Moms Low Cholesterol Tied to Preemie Births
7. IVF technique enables pregnancy without multiple births, Stanford researchers find
8. Fetal cell transplant could be a hidden link between childbirth and reduced risk of breast cancer
9. Sue Birth Control Companies for Your Health, Says American Life League
10. Maternal Mortality Declining in Middle-income Countries; Women Still Die in Pregnancy and Childbirth in Low-income Countries
11. UF researchers track genetic journey of HIV from birth to death
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2016)... ... May 02, 2016 , ... Avid ... Jimi Hendrix Merriweather Post Pavilion in Columbia, Maryland concert posters. Dail Beeghley hit ... concert was held on August 16. According to Hawley, “The Pavilion was built ...
(Date:5/1/2016)... Birmingham, Lake Orion, Clarkston, Metamora, Michigan (PRWEB) , ... ... ... and a guide on their website, http://www.womensexcellence.com that gives new mothers ... of:, · Warning signs and when to call, · Adjusting to baby postpartum, ...
(Date:5/1/2016)... ... 01, 2016 , ... Outdoor Growing Bans Are Sweeping California, which states are ... law in the hands of the local communities to decide each county’s fate ... counties to vote on growing regulations by 3/1/2016 or be forced to follow how ...
(Date:4/30/2016)... ... ... Serenity Recovery, a substance abuse treatment center located in Central Michigan that takes ... of the more popular of their optional courses, the Yoga Class. With footage from ... the Yoga class instructor, this video is available for viewing on the Serenity Recovery ...
(Date:4/30/2016)... , ... April 30, 2016 , ... ... Carol Francis Talk Radio with Hypnotherapist, Mary O'Maley. What is hypnosis and ... habit control (substances, smoking, weight control), pain relief (chronic and acute), birthing processes ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... , April 27, 2016 ... titled, "Skincare Devices Market - Global Industry Analysis, Size, ... to the report, the global skincare devices market was ... anticipated to expand at a CAGR of 10.1% from ... 2023. Browse the full Skincare Devices Market (Treatment ...
(Date:4/27/2016)... 27, 2016  Bayer Animal Health today announced ... the University of Florida College of Veterinary Medicine, ... in Communication Award (BECA). Brittany was selected from ... a total of $70,000 in scholarship funds through ... Bayer has provided a total of $232,500 in ...
(Date:4/27/2016)... 27, 2016 Oasmia Pharmaceutical ... of a new generation of drugs within human ... results for Paclical/Apealea in the Phase III study ... epithelial ovarian cancer. These preliminary results showed non-inferiority ... with carboplatin versus Taxol in combination with carboplatin. ...
Breaking Medicine Technology: