Navigation Links
Smoking Damages DNA Within Minutes, Research Shows
Date:1/17/2011

SATURDAY, Jan. 15 (HealthDay News) -- Cigarettes start to destroy a smoker's DNA within minutes of inhaling, new research indicates, suggesting that the habit causes immediate genetic damage and quickly raises the short-term risk for cancer.

"The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," lead study author Stephen S. Hecht, from the Masonic Cancer Center and department of pharmacology at the University of Minnesota in Minneapolis, said in a news release from the American Chemical Society.

Hecht and his colleagues reported their observations in the current issue of the journal Chemical Research in Toxicology.

In their research, the investigators focused on a class of cancer-causing culprits found in cigarette smoke called polycyclic aromatic hydrocarbons, or PAHs.

PAHs are known to inflict damage on DNA and are therefore thought to play a large role in the onset of lung cancer, a disease that the researchers pointed out has been linked to the loss of 3,000 lives a day worldwide, mostly as a consequence of smoking.

To date, however, little had been known about the exact mechanism by which PAH exposure causes disease.

To better understand the risks, Hecht's team conducted what they called a "unique" analysis, by labeling and tracking a single PAH -- phenanthrene -- through the bodies of 12 volunteer smokers.

The study authors noted that this approach was "the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet."

The results: having rapidly transformed in the body into a known toxin, the PAH in question began to cause havoc on the DNA of the smokers within just 15 to 30 minutes after smoking.

The velocity of the cancer-causing process surprised the research team. They said the speed with which the potentially lethal DNA assault began was comparable to having injected the PAH directly into an individual's bloodstream.

More information

For more on the health risks posed by smoking, visit the U.S. National Cancer Institute.

-- Alan Mozes

SOURCE: American Chemical Society, news release, Jan. 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Europe reins in the smoking habit
2. Studies Decipher How Anti-Smoking Drugs Work
3. Smoking may worsen pain for cancer patients
4. Apartment-dwelling children in nonsmoking units still exposed
5. Treating PTSD and Smoking Together Best Way to Help Vets Kick Cigarettes
6. Watching R-rated Movies Ups Odds of Teens Smoking
7. Heavy Smoking May Double Rheumatoid Arthritis Risk in Blacks
8. Smoking Still Allowed at 1 in 4 Major U.S. Airports
9. When video games get problematic so do smoking, drug use and aggression
10. Minneapolis Study Points to Sharp Drop in Smoking Rates
11. Smoking among some adults dropped dramatically in past three decades
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking Damages DNA Within Minutes, Research Shows
(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... “America On ... Christian identity. “America On The Brink” is the creation of published author, William ... several great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... ANGELES (PRWEB) , ... October 12, 2017 , ... ... Parsa Mohebi Hair Restoration, has recently contributed a medical article to the newly ... on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/25/2017)... Sept. 25, 2017   Montrium , an ... solutions, today—from the IQPC Trial Master Files & ... NL)—announced that EastHORN Clinical Services has selected ... and TMF management. EastHORN, a leading European contract ... to increase transparency to enable greater collaboration with ...
(Date:9/19/2017)... medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed sound energy ... ... Jim Bertolina, PhD ... Tom Tefft ... executive Josh Stopek , PhD, who has led R&D and business development teams at ...
Breaking Medicine Technology: