Navigation Links
Smoking Damages DNA Within Minutes, Research Shows
Date:1/17/2011

SATURDAY, Jan. 15 (HealthDay News) -- Cigarettes start to destroy a smoker's DNA within minutes of inhaling, new research indicates, suggesting that the habit causes immediate genetic damage and quickly raises the short-term risk for cancer.

"The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," lead study author Stephen S. Hecht, from the Masonic Cancer Center and department of pharmacology at the University of Minnesota in Minneapolis, said in a news release from the American Chemical Society.

Hecht and his colleagues reported their observations in the current issue of the journal Chemical Research in Toxicology.

In their research, the investigators focused on a class of cancer-causing culprits found in cigarette smoke called polycyclic aromatic hydrocarbons, or PAHs.

PAHs are known to inflict damage on DNA and are therefore thought to play a large role in the onset of lung cancer, a disease that the researchers pointed out has been linked to the loss of 3,000 lives a day worldwide, mostly as a consequence of smoking.

To date, however, little had been known about the exact mechanism by which PAH exposure causes disease.

To better understand the risks, Hecht's team conducted what they called a "unique" analysis, by labeling and tracking a single PAH -- phenanthrene -- through the bodies of 12 volunteer smokers.

The study authors noted that this approach was "the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet."

The results: having rapidly transformed in the body into a known toxin, the PAH in question began to cause havoc on the DNA of the smokers within just 15 to 30 minutes after smoking.

The velocity of the cancer-causing process surprised the research team. They said the speed with which the potentially lethal DNA assault began was comparable to having injected the PAH directly into an individual's bloodstream.

More information

For more on the health risks posed by smoking, visit the U.S. National Cancer Institute.

-- Alan Mozes

SOURCE: American Chemical Society, news release, Jan. 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Europe reins in the smoking habit
2. Studies Decipher How Anti-Smoking Drugs Work
3. Smoking may worsen pain for cancer patients
4. Apartment-dwelling children in nonsmoking units still exposed
5. Treating PTSD and Smoking Together Best Way to Help Vets Kick Cigarettes
6. Watching R-rated Movies Ups Odds of Teens Smoking
7. Heavy Smoking May Double Rheumatoid Arthritis Risk in Blacks
8. Smoking Still Allowed at 1 in 4 Major U.S. Airports
9. When video games get problematic so do smoking, drug use and aggression
10. Minneapolis Study Points to Sharp Drop in Smoking Rates
11. Smoking among some adults dropped dramatically in past three decades
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking Damages DNA Within Minutes, Research Shows
(Date:12/7/2016)... ... December 07, 2016 , ... Augustine Insurance Agency, a locally ... business owners in the greater Dallas metropolitan area, is announcing a charity event ... , Established in 2009 by active police professionals in the Dallas region, the ...
(Date:12/7/2016)... ... 2016 , ... A. Kevin Spann Insurance, a New York-based firm offering insurance ... launching a charity drive to raise funds that will benefit the Marine Corps League. ... and Navy FMF Corpsmen. Working closely with the MCL, the A. Kevin Spann team ...
(Date:12/7/2016)... ... December 07, 2016 , ... The Honolulu cosmetic ... redesigned website, which launched October 17, 2016, features comprehensive information regarding a wide ... layout. Visitors and patients can discover the latest clinical dermatology treatments for medical ...
(Date:12/7/2016)... ... 07, 2016 , ... Texas Premier Locksmith , a ... by unethical locksmith companies and is urging Search Engines to improve verification methods ... Premier Locksmith, these fraudulent locksmith services take advantage of consumers locked out of ...
(Date:12/7/2016)... ... December 07, 2016 , ... "ProBrand Flip allows FCPX editors ... said Christina Austin - CEO of Pixel Film Studios. , ProBrand Flip includes 30 ... drop zones. Editors can select from a variety of flip book animations. In Addition, ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... , Dec. 7, 2016   Arena Pharmaceuticals, ... that it has completed enrollment in the ralinepag phase ... agonist targeting the prostacyclin pathway for the treatment of ... patients at sites globally. "This marks an ... evidence of our strategic focus on our pipeline," said ...
(Date:12/7/2016)... 2016   Rx Savings Solutions has partnered with ... its Public Employees Insurance Agency (PEIA) to offer more than ... healthcare software, ultimately saving money on their prescriptions. ... members with access to our software that will alert them ... therapy can be found," says Michael Rea , founder ...
(Date:12/7/2016)... India , December 7, 2016 According to ... (Services, Software), Delivery Mode, Product Type (Integrated, Standalone), Model (Knowledge-Based), Type (Therapeutic, ... MarketsandMarkets, The CDSS Market is expected to reach USD 1,519.2 Million by ... Continue Reading ... ...
Breaking Medicine Technology: