Navigation Links
Smoking Damages DNA Within Minutes, Research Shows
Date:1/17/2011

SATURDAY, Jan. 15 (HealthDay News) -- Cigarettes start to destroy a smoker's DNA within minutes of inhaling, new research indicates, suggesting that the habit causes immediate genetic damage and quickly raises the short-term risk for cancer.

"The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," lead study author Stephen S. Hecht, from the Masonic Cancer Center and department of pharmacology at the University of Minnesota in Minneapolis, said in a news release from the American Chemical Society.

Hecht and his colleagues reported their observations in the current issue of the journal Chemical Research in Toxicology.

In their research, the investigators focused on a class of cancer-causing culprits found in cigarette smoke called polycyclic aromatic hydrocarbons, or PAHs.

PAHs are known to inflict damage on DNA and are therefore thought to play a large role in the onset of lung cancer, a disease that the researchers pointed out has been linked to the loss of 3,000 lives a day worldwide, mostly as a consequence of smoking.

To date, however, little had been known about the exact mechanism by which PAH exposure causes disease.

To better understand the risks, Hecht's team conducted what they called a "unique" analysis, by labeling and tracking a single PAH -- phenanthrene -- through the bodies of 12 volunteer smokers.

The study authors noted that this approach was "the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet."

The results: having rapidly transformed in the body into a known toxin, the PAH in question began to cause havoc on the DNA of the smokers within just 15 to 30 minutes after smoking.

The velocity of the cancer-causing process surprised the research team. They said the speed with which the potentially lethal DNA assault began was comparable to having injected the PAH directly into an individual's bloodstream.

More information

For more on the health risks posed by smoking, visit the U.S. National Cancer Institute.

-- Alan Mozes

SOURCE: American Chemical Society, news release, Jan. 15, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Europe reins in the smoking habit
2. Studies Decipher How Anti-Smoking Drugs Work
3. Smoking may worsen pain for cancer patients
4. Apartment-dwelling children in nonsmoking units still exposed
5. Treating PTSD and Smoking Together Best Way to Help Vets Kick Cigarettes
6. Watching R-rated Movies Ups Odds of Teens Smoking
7. Heavy Smoking May Double Rheumatoid Arthritis Risk in Blacks
8. Smoking Still Allowed at 1 in 4 Major U.S. Airports
9. When video games get problematic so do smoking, drug use and aggression
10. Minneapolis Study Points to Sharp Drop in Smoking Rates
11. Smoking among some adults dropped dramatically in past three decades
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Smoking Damages DNA Within Minutes, Research Shows
(Date:3/28/2017)... ... 2017 , ... Alert Sentry Group LLC., a leader in the Personal Emergency ... iSAFE and the iSAFE Plus. These iSAFE products are the most affordable and most ... and iSAFE Plus offer direct GPS Location and two-way calling with the push of ...
(Date:3/28/2017)... ... ... WHO: , Dr. Paul Thomas; Dr. Brian Hooker; Dr. Judy Mikovits; Dr. ... will speak to the press on behalf of over 200 doctors, scientists, and scientific ... commission. , WHERE: , Zenger Room, National Press Club, 529 14th Street NW, ...
(Date:3/28/2017)... VA (PRWEB) , ... March 28, 2017 , ... The ... Still, MHA, FRBMA, has begun to serve as its new executive director. Mr. Still ... the Executive Search Committee. , “Bob, as he is known to our members, ...
(Date:3/28/2017)... ... March 28, 2017 , ... Award-winning ... will begin serving as new board chair for Orange County health care system ... the remainder of soon-to-be former chair Mark Refowitz’s term, which runs through June ...
(Date:3/28/2017)... ... March 28, 2017 , ... ... of two biometric time and attendance tracking products: the new NCheck Cloud Bio ... Cloud Bio Attendance uses biometric face recognition to enable users to check in ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... SAN MATEO, Calif. , March 27, 2017 ... has been acquired by Ethicon, a division of ... Reflux Management System for the treatment of gastro-esophageal ... on magnetic sphincter augmentation (MSA) technology and the ... European medical centers. Torax Medical was ...
(Date:3/27/2017)... BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage ... AGI-134, an immunotherapy for the treatment of multiple cancers, obtained ... featured at the upcoming American Association for Cancer Research ... to be held on April 1-5, 2017. ... An abstract titled ...
(Date:3/27/2017)... SAN FRANCISCO , March 27, 2017 ...  is expected to reach USD 16.0 billion by 2025, ... Inc. The growing prevalence of chronic diseases is anticipated ... clinical chemistry analyzers, which thereby widens the scope for ... of geriatric and bariatric population, which is highly susceptible ...
Breaking Medicine Technology: