Navigation Links
Smoking-Cessation Drug Chantix Linked to Heart Problems

THURSDAY, June 16 (HealthDay News) -- The quit-smoking drug Chantix may lead to a small but increased risk of heart problems in people with cardiovascular disease, the U.S. Food and Drug Administration said Thursday.

In a study of 700 smokers with cardiovascular disease who were undergoing treatment with Chantix or a placebo, researchers saw a small but "statistically significant" greater risk of chest pain, non-fatal heart attacks and other cardiovascular problems in patients taking the quit-smoking drug, the FDA said.

Details of the new findings will be shared with doctors and will be included in the drug's medication guide to patients, the agency said.

In July 2009, the FDA mandated that Chantix (varenicline tartrate) and a second smoking-cessation drug, Zyban, carry a "black-box" warning about the potential risks of psychiatric problems, including depression and suicidal thoughts.

In its announcement Thursday, the FDA noted that smoking is a major contributor to cardiovascular disease, the number one killer of Americans. So doctors and their patients should weigh the "known benefits of Chantix against its potential risks when deciding to use the drug in smokers with cardiovascular disease," the agency said in a statement on its website.

Patients taking Chantix, which received FDA approval in 2006, should contact their health-care professional if they experience new or worsening symptoms of cardiovascular disease.

The FDA said it will continue to evaluate the risks and benefits associated with Chantix and is requiring the manufacturer -- Pfizer Inc. -- to conduct an analysis of all previous randomized, placebo-controlled trials of the drug. The agency said it will release those findings to the public when they become available.

In a statement, Pfizer pointed out that smoking is a key risk factor for heart disease, and quitting the habit brings heart benefits that are "immediate and substantial," the Wall Street Journal reported. Pfizer agreed that patients should talk to their doctors to "determine what medications are right for them."

More information

For more on how to quit smoking, visit the U.S. Centers for Disease Control and Prevention.

-- HealthDay staff

SOURCE: U.S. Food and Drug Administration, June 16, 2011; Wall Street Journal

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. South Carolina Attorney Says Legal Options Still Available To Those Harmed By Chantix
2. Web- and phone-based counseling work well to quit smoking with Chantix
3. Molecular pathways linked to sex, age affect outcomes in lung cancer
4. Physical Changes in Brain Linked to Altered Spirituality
5. Migraine Linked to Increased Heart Attack Risk
6. First Gene Variants Linked to Stuttering Discovered
7. Flat Head Syndrome Linked to Developmental Delays
8. Untreated poor vision in elderly linked to dementia, University of Michigan study shows
9. Genetic Mutation Linked to Prostate Cancer in Blacks
10. Sleep More, Lose Weight – Sleeplessness Linked to Obesity
11. Antibodies linked to cardiovascular disease increase in patients with active lupus
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution ... the emergency ambulance transport experience for the millions of people who require these ... disrupted the taxi industry through the use of technology. Now, SmartEMS has put ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many of ... beholder, according to experts who offered insights and commentary in the current issue of ... full issue, click here . , For the American Society of Clinical Oncology ...
(Date:6/26/2016)... Viejo, California (PRWEB) , ... June 26, 2016 , ... ... Final Cut Pro X. , "Film editors can give their videos a whole new ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains ...
(Date:6/26/2016)... ... , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a ... fitness app plans to fix the two major problems leading the fitness industry today:, ... type program , They don’t eliminate all the reasons people quit their exercise ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American ... Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. ... including advance care planning, healthcare costs and patient and family engagement. , AIR ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 26, 2016 Story ... operating models within the health care industry is causing ... efficiency , Deloitte offers a suite of solutions ... issues impacting efficient cost optimization: labor resource analysis, revenue ... services facilitate better outcomes and better economics ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... 24, 2016   Bay Area Lyme Foundation ... Dean Center for Tick Borne Illness , Harvard ... MIT Hacking Medicine, University of California, Berkeley, and ... the five finalists of Lyme Innovation , ... than 100 scientists, clinicians, researchers, entrepreneurs, and investors ...
Breaking Medicine Technology: