Navigation Links
Smoking-Cessation Drug Chantix Linked to Heart Problems
Date:6/16/2011

THURSDAY, June 16 (HealthDay News) -- The quit-smoking drug Chantix may lead to a small but increased risk of heart problems in people with cardiovascular disease, the U.S. Food and Drug Administration said Thursday.

In a study of 700 smokers with cardiovascular disease who were undergoing treatment with Chantix or a placebo, researchers saw a small but "statistically significant" greater risk of chest pain, non-fatal heart attacks and other cardiovascular problems in patients taking the quit-smoking drug, the FDA said.

Details of the new findings will be shared with doctors and will be included in the drug's medication guide to patients, the agency said.

In July 2009, the FDA mandated that Chantix (varenicline tartrate) and a second smoking-cessation drug, Zyban, carry a "black-box" warning about the potential risks of psychiatric problems, including depression and suicidal thoughts.

In its announcement Thursday, the FDA noted that smoking is a major contributor to cardiovascular disease, the number one killer of Americans. So doctors and their patients should weigh the "known benefits of Chantix against its potential risks when deciding to use the drug in smokers with cardiovascular disease," the agency said in a statement on its website.

Patients taking Chantix, which received FDA approval in 2006, should contact their health-care professional if they experience new or worsening symptoms of cardiovascular disease.

The FDA said it will continue to evaluate the risks and benefits associated with Chantix and is requiring the manufacturer -- Pfizer Inc. -- to conduct an analysis of all previous randomized, placebo-controlled trials of the drug. The agency said it will release those findings to the public when they become available.

In a statement, Pfizer pointed out that smoking is a key risk factor for heart disease, and quitting the habit brings heart benefits that are "immediate and substantial," the Wall Street Journal reported. Pfizer agreed that patients should talk to their doctors to "determine what medications are right for them."

More information

For more on how to quit smoking, visit the U.S. Centers for Disease Control and Prevention.

-- HealthDay staff

SOURCE: U.S. Food and Drug Administration, June 16, 2011; Wall Street Journal


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. South Carolina Attorney Says Legal Options Still Available To Those Harmed By Chantix
2. Web- and phone-based counseling work well to quit smoking with Chantix
3. Molecular pathways linked to sex, age affect outcomes in lung cancer
4. Physical Changes in Brain Linked to Altered Spirituality
5. Migraine Linked to Increased Heart Attack Risk
6. First Gene Variants Linked to Stuttering Discovered
7. Flat Head Syndrome Linked to Developmental Delays
8. Untreated poor vision in elderly linked to dementia, University of Michigan study shows
9. Genetic Mutation Linked to Prostate Cancer in Blacks
10. Sleep More, Lose Weight – Sleeplessness Linked to Obesity
11. Antibodies linked to cardiovascular disease increase in patients with active lupus
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... ... ... is famous for gift giving with flowers, chocolates and other tokens of affection meant to ... more than 5.6 million Americans suffering with Alzheimer’s, those store bought gifts - no ... lives they’ve led and the people they’ve touched. , That’s why Give ...
(Date:2/8/2016)... ... 2016 , ... Steve Helwig & Associates Insurance & Financial, serving the families ... teamed up with Citizens Opposed to Domestic Abuse in support of its efforts to ... those victimized by the fear of violence in their own homes, donations may now ...
(Date:2/8/2016)... ... February 08, 2016 , ... Remember the old saying “rub some ... to Perry A~, author of “Calcium Bentonite Clay” the health benefits of integrating clay ... and detoxifying the body. , A former motivational speaker, Perry A~ has since dedicated ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... this important news! AHCC and the Home Health and Hospice ICD-10 Transition Workgroup ... for official ICD coding guidance and clarifications, to address concerns over the use ...
(Date:2/8/2016)... ... February 08, 2016 , ... According to research by the ... dental technicians to be certified or obtain continuing education. To increase patient awareness ... In Your Mouth?” campaign to inform dentists and patients about the possible lack ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... 8, 2016   GS1 US will hold ... them through GS1 Standards implementation to address the requirements ... Device Identification (UDI) rule. Scott Brown ... Gibson , senior director industry development, medical devices, GS1 ... GS1 US --> Scott Brown ...
(Date:2/8/2016)... Pa. , Feb. 8, 2016   ... November Research Group (NRG),s pharmacovigilance technology services ... system-related consulting services and an Oracle Argus Specialized ... services to Life Sciences companies. ... and expands HighPoint,s life sciences capabilities and provides ...
(Date:2/8/2016)... , Switzerland and PALO ALTO, Calif. ... in biological and chemical manufacturing, and Kodiak Sciences Inc., ... the treatment of retinal disease, announced today agreements for ... agreement, Lonza will manufacture material at multiple sites, including ... --> --> Retinal diseases, ...
Breaking Medicine Technology: