Navigation Links
Smokers treated for brain aneurysm with coils at higher risk of recurrence
Date:3/19/2008

(PHILADELPHIA) Cigarette smokers who were treated for cerebral aneurysms with coil embolization (blocking of a blood vessel) are at greater risk of developing another aneurysm, say neurological surgeons at Jefferson Hospital for Neuroscience in Philadelphia in the first-known study of its kind.

In a paper published in the April issue of the Journal of Neurosurgery, researchers found there was an increased risk of recanalization (re-opening), especially in low-grade aneurysmal subarrachnoid hemorrhage (aneurysm) patients with a history of cigarette smoking, says Erol Veznedaroglu, M.D., associate professor of Neurological Surgery and director of the Division of Neurovascular Surgery and Endovascular Neurosurgery at Jefferson Medical College of Thomas Jefferson University and Thomas Jefferson University Hospital.

To our knowledge no study documenting a correlation between aneurysm recanalization and a history of cigarette smoking history has previously been reported in the literature, the authors say. Annually, aneurysmal subarachnoid hemorrhages are found in approximately one case per 10,000.

The studys authors conducted a retrospective chart review of all cases involving patients admitted to their institution in 2003 for treatment of a cerebral aneurysm by coil embolization or coiling.

In coiling, a catheter is inserted into an artery in the groin, then advanced into the affected artery in the brain. The surgeon then places one or more tiny coils through the catheter into the aneurysm. The body responds by forming a blood clot around the coil, blocking off the aneurysm.

The authors searched for any correlation among the location and size of the treated aneurysm, the incidence of coil compaction, and the history of smoking as factors for recurrence. But there was no significant indication that aneurysm location and size, type of coil and packing density were causing the higher risk.

Of the various factors that lead to a predisposition for these cerebral aneurysms, cigarette smoking is the only factor that has consistently been identified in all the populations studied, and is also the most easily preventable, says Dr. Veznedaroglu. The quantity of cigarettes smoked was also found to have an impact on the increased risk of developing an aneurysm, he adds.

Cigarette smoking has been directly correlated with an increased risk of intracranial aneurysm formation and growth, the authors say. And despite this evidence, more than one third of prior smokers continue to use nicotine after suffering an aneurysm, especially patients who started smoking at a young age and those with a history of depression or alcohol abuse.

However in the group of patient cases reviewed, the authors did not find a significant trend between smoking cessation after aneurysm treatment and the incidence of aneurysm recurrence, but the sample size was not large enough to demonstrate statistical significance.

Nevertheless, patients with known cerebral aneurysms should be aggressively counseled about the risk of cigarette smoking, Dr. Veznedaroglu says.


'/>"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Related medicine news :

1. Magnesium May Lower Risk for Some Strokes in Male Smokers
2. Certain vitamin supplements may increase lung cancer risk, especially in smokers
3. Earlier Colon Cancer Screens Urged for Smokers
4. Older Smokers More Likely to Deny Habit
5. Smokers might benefit from earlier colon cancer screening
6. Smokers Sleep Less Soundly
7. Number of Russian women smokers has doubled since Soviet collapse
8. Famed Attorney Willie Gary Files $10.6 Billion in Lawsuits against Big Tobacco Companies on Behalf of Florida Smokers and their Families
9. California Dental Hygienists Urge Smokers to Kick the Habit in 2008
10. Smokers Brain Centers Activate During Nicotine Cravings
11. HealthCentral.coms New Stop Smoking Site Provides Expert Advice, Supportive Community to Help Smokers Quit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... ... March 27, 2017 , ... ... to the OSEHRA popHealth Community in 2014. It is the culmination ... the Developer Open Source Project Group. OSEHRA Organizational Member Zato Health co-funded the ...
(Date:3/27/2017)... ... March 27, 2017 , ... ... announced it will co-exhibit with technology partners LG Business Solutions at ATARC ... Metro Center in Washington D.C., will provide education and examination into the mobility ...
(Date:3/27/2017)... ... March 27, 2017 , ... Adding to its ... Journal of Medicine and NEJM Journal Watch, announces the release of NEJM ... by a panel of pediatricians from leading medical centers. The content was then ...
(Date:3/27/2017)... Rock, AR (PRWEB) , ... March 27, 2017 , ... ... CMSA National Board of Directors on June 30, 2017. CMSA’s membership has elected ... In addition to our current Military Advisory position, a new VA Advisory position has ...
(Date:3/27/2017)... ... March 27, 2017 , ... Osteitis pubis may be ... groin injury, it occurs when the muscles around the pelvis become inflamed. Over ... the lower torso, as well as accompanying tenderness and weakness. Without proper intervention, ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... , March 27, 2017 The ... reach USD 16.0 billion by 2025, according to a ... prevalence of chronic diseases is anticipated to be responsible ... which thereby widens the scope for growth during the ... bariatric population, which is highly susceptible to chronic diseases, ...
(Date:3/27/2017)...  Twist Bioscience, a company accelerating science and innovation ... raised an additional $33 million. To date, Twist Bioscience ... "It is an exciting time to be leading ... to deliver industry-leading gene volume to our customers, enabling ... Leproust, Ph.D., CEO of Twist Bioscience. "We welcome the ...
(Date:3/27/2017)... , March 27, 2017   Genprex, Inc. , a ... Julien Pham , MD, the Company,s Chief Operating Officer, is ... conferences. Sachs 5th Annual Cancer BioPartnering & Investment ... New York, NY ... BioCentury 24th Annual Future Leaders in Biotech ...
Breaking Medicine Technology: