Navigation Links
Smokers' Brain Centers Activate During Nicotine Cravings

Finding could lead to better smoking-cessation aids

WEDNESDAY, Dec. 19 (HealthDay News) -- Specific areas of the brain show increased activation in smokers who are deprived of nicotine, says a University of Pennsylvania study.

The finding may boost understanding of cigarette cravings, a key risk factor for relapse among people trying to kick the habit, the researchers said.

"There have been several brain imaging studies showing how subjects respond to visual, smoking-related cues, such as a picture of a cigarette or of someone smoking," senior study author Caryn Lerman, director of the Transdisciplinary Tobacco Use Research Center, said in a prepared statement. "However, less is known about the neural basis of urges that arise naturally as a result of nicotine deprivation. This study was designed to help fill this research gap."

The study included 15 regular smokers whose brain blood flow was measured on two separate occasions. The participants had a cigarette within an hour of having the first brain scan, and then abstained from smoking overnight before the second scan.

The results showed that cravings to smoke are associated with increased activation in brain regions that play a role in attention, behavioral control, memory and reward.

"The craving assessments used in our study predict relapse in smoking-cessation treatment. If validated in larger studies, these results may have important clinical implications. For example, perfusion MRI may aid in the identification of smokers at increased risk for relapse who require more intensive therapy," Lerman said.

The study is published in the Dec. 19 issue of The Journal of Neuroscience.

More information

The American Cancer Society offers a guide to quitting smoking.

-- Robert Preidt

SOURCE: University of Pennsylvania School of Medicine, news release, Dec. 18, 2007

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Teens who see more smoking in movies may have increased risk of becoming established smokers
2. Smokers More Likely to Develop Dementia
3. Help is Available for Smokers Who Want to Quit as Minnesotas Smoke-Free Law Takes Effect Oct. 1
4. First Puff Can Turn Kids Into Smokers: Study
5. Statins reduce loss of function, keeping old lungs young - even in smokers
6. Blood Test Catches Secret Smokers
7. Smokers Remain Unaware of the Health Effects of Smoking, New Survey Finds
8. Smokers Cost Medicaid System Nearly $10 Billion
9. Studies of 20,000 smokers show quit rates double with counseling and free nicotine patches
10. Smoking Cessation Rates Double With Intensive Counseling and Free Nicotine Replacement Therapy, Studies of 20,000 Smokers Show
11. FSU researcher lands $3.3 million grant to help smokers kick habit
Post Your Comments:
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from reveals that behind the tendency to set ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016 One of Australia,s successful ... of a new biotechnology company, Noxopharm Limited [ABN 50 608 966 ... and to list on the ASX. Noxopharm is a ... enter a Phase 1 clinical study later this year. ... of the biggest problems facing cancer patients - the ability of ...
(Date:6/26/2016)... , June 27, 2016 Jazz Pharmaceuticals ... waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of ... acquisition of Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: ... p.m. (Eastern Daylight Time). As previously announced ... into a definitive merger agreement under which Jazz Pharmaceuticals ...
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
Breaking Medicine Technology: