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Smoked cannabis proven effective in treating neuropathic pain
Date:10/24/2007

ave an impact on the pain, he said.

The results, showing a medium-dose (4% THC by weight) of cannabis to be an effective analgesic, converged with results from the CMCRs first published study, a paper by UCSF researcher Donald Abrams, M.D. published in the journal Neurology in February 2007. In that randomized placebo-controlled trial, patients smoking the same dose of cannabis experienced a 34% reduction in HIV-associated sensory neuropathy paintwice the rate experienced by patients receiving a placebo.

This study helps to build a case that cannabis does have therapeutic value at a medium-dose level, said Grant. It also suggests that higher doses arent necessarily better in certain situations something also observed with other medications, such as antidepressants.

The researchers stated that more and larger studies need to be conducted to measure the efficacy of cannabis, noting that medical marijuana could play an important role in treating patients who dont respond well to the usual pain relievers or cant tolerate drugs such as ibuprofen or opioids used for severe pain.

The results of this study might help guide others doing clinical research into pain management, said Wallace.


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Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

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