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Smallpox Vaccine Clinical Study Now Enrolling at Avail Clinical Research near Orlando, Florida; Accepting Healthy M/F Age 18-40
Date:3/27/2013

Orlando, Florida (PRWEB) March 27, 2013

*Avail Clinical Research conducts Clinical Trials near Orlando, FL. For more information about participating in this Vaccine Clinical Trial, please visit our website or contact us directly at (386) 310-1334

BACKGROUND & SCIENTIFIC RATIONALE

Despite the fact that the World Health Organization (WHO) officially declared successful global eradication of smallpox in 1980, the existence of variola stockpiles and the threat of bioterrorism demands to maintain immunity to smallpox through vaccination.

After the events of September 11th, 2001, concern over the use of bioweapons as agents of terrorism increased. As mass vaccination programs halted more than 30 years ago, it is estimated that the majority of the world population has no existing immunity to smallpox, and as such, the release of this highly contagious virus would have devastating effects.

As a consequence, there is an urgent need for a safe and efficacious vaccine to protect the public against smallpox.

PRIMARY OBJECTIVE

-To assess the consistency of three consecutively produced IMVAMUNE® lots.

SECONDARY OBJECTIVE

-To assess uncommon adverse reactions, in particular any cardiac sign and symptom indicating a case of myo-/pericarditis, and to compare the frequency of those reactions against placebo.

-To collect vaccinia-specific humoral immune response data.

INCLUSION CRITERIA

1. Male and female subjects, 18 to 40 years of age

2. The subject has read, signed and dated the informed consent form, having been advised of the
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