Navigation Links
Smallest full support heart assist device on trial at Northwestern Memorial
Date:4/27/2009

CHICAGO - Northwestern Memorial Hospital's Bluhm Cardiovascular Institute is the first center in Chicago and among the first in the country to implant a new experimental left ventricular assist device (LVAD) into subjects with advanced heart failure, a condition where the heart cannot pump enough blood to the body's organs. The HeartWare Ventricular Assist System (HeartWare System) features the HVAD Pump, the smallest LVAD to provide full cardiac support currently under investigation in the United States. The HeartWare System is intended as a bridge to heart transplantation. Northwestern Memorial surgeons have implanted four subjects with the device, and are the first in the country to transplant a subject as part of this trial.

Individuals with advanced heart failure experience symptoms such as swelling, fatigue, shortness of breath and are not able to exert themselves. Medications are often successful for managing symptoms in the earlier stages of heart failure, but for patients in the late-stages heart transplantation is considered the best treatment option. However, with just over 2,000 donor hearts becoming available each year, the wait for a transplant can be long. The smaller model is being studied as a less cumbersome LVAD procedure in subjects with advanced-stage heart failure who need support to survive until a donor heart becomes available. In subsequent trials the HVAD Pump will be trialed in subjects that are not transplant candidates.

Edwin McGee Jr., MD, the principal investigator of the trial, cardiac surgeon and the surgical director of Heart Transplantation and Mechanical Assistance at the Bluhm Cardiovascular Institute, lead the team that implanted the four subjects. The national clinical trial hopes to enroll up to 150 subjects. Twenty-two subjects have been enrolled in the U.S to date.

"The small size and unique configuration of this particular model allows us to place it adjacent to the ventricle itself, as opposed to implanting the device in the abdominal wall," commented Dr. McGee. "This is a major step forward, as it is intended to reduce the potential risks associated with a more extensive surgery such as bleeding and infections. We are also able to cast a wider net of potential subjects and can include more women in the trials since the device is significantly smaller than previous models."

The device is a tiny centrifugal blood pump, with a levitating impeller that spins to continuously move blood from the heart to the rest of the body. A driveline cable attaches to the pump and connects to a portable controller, powered by a pair of battery packs, worn by the subject allowing for mobility.

According to the American Heart Association, 4.9 million patients in the United States suffer from heart failure, with an additional 550,000 diagnosed each year. The National Institutes of Health estimates that in the US, approximately 100,000 patients per year could benefit from an LVAD.

"Heart failure is a growing epidemic in this country and we hope that this trial will lead to better outcomes and fewer complications for patients with severe heart failure," said Dr. McGee. This LVAD is the next step in the evolution of heart assist devices, which, in the future, could result in a fully-implantable model.


'/>"/>

Contact: Amy Dobrozsi
adobrozs@nmh.org
312-926-5900
Northwestern Memorial Hospital
Source:Eurekalert

Related medicine news :

1. VIDEO from Medialink and Abiomed: Worlds Smallest Heart Pump Receives 510(K) Clearance from FDA
2. LightAir Cleans the Air From the Smallest and Most Dangerous Particles Without Generating Ozone
3. Smallest Air Pollution Particles Hurt Heart Most
4. VIDEO from Medialink and Siemens: Worlds Smallest Ultrasound Package Launches in the U.S.
5. Good Imaging Now Comes in the Worlds Smallest Ultrasound Package
6. Medicare Offers Smallest Rise in Premiums in 6 Years
7. Thermal Angel Supports Infection Control During the Golden Hour
8. Teamsters, Area Unions Rally in Support of Rural/Metro Workers
9. Cardinal Rigali Praises House Re-Introduction of Pregnant Women Support Act, Urges Co-Sponsorship
10. New Evidence Supports Efficacy and Value of Smith & Nephew NPWT Products
11. Wounded Warrior Project (WWP) Announces Support for Soldier Ride from Boston Scientific
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson ... Recently, he has implemented orthobiologic procedures as a method for treating his patients. ... the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons ...
(Date:6/25/2016)... Canada (PRWEB) , ... June 25, 2016 , ... Conventional ... pursuit of success. In terms of the latter, setting the bar too high can ... risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... June 23, 2016  In a startling report released today, ... residents by lacking a comprehensive, proven plan to eliminate prescription opioid ... ranking of how states are tackling the worst drug crisis in ... states – Kentucky , New Mexico ... . Of the 28 failing states, three – ...
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
Breaking Medicine Technology: