Navigation Links
Sleep switch found in fruit flies
Date:6/23/2011

Rather than count sheep, drink warm milk or listen to soothing music, many insomniacs probably wish for a switch they could flick to put themselves to sleep.

Scientists at Washington University School of Medicine in St. Louis have discovered such a switch in the brains of fruit flies. In a study appearing June 24 in Science, the researchers show that a group of approximately 20 cells in the brains of fruit flies controls when and how long the flies sleep. Slumber induced through this sleep switch was essential to the creation of long-term memory, directly proving a connection between memory and sleep that scientists have long suspected.

"This is exciting because this induced sleep state so far appears to be very similar to spontaneous sleep," says Paul Shaw, PhD, associate professor of neurobiology. "That means we can manipulate these cells to explore a whole new realm of questions about the purposes of sleep. Such studies might one day lead us to more natural ways of inducing sleep in humans."

The key cells are found in an area of the fly brain known as the dorsal fan-shaped body. Scientists in Shaw's lab genetically modified the cells to increase their activity. One effect of making these cells more active was that adult flies slept for an additional seven hours a day.

When scientists added a gene that increases the cells' activity only at warmer temperatures, they could determine when and how long flies would sleep by simply adjusting the temperature in the flies' habitats.

To analyze the similarity of induced sleep to spontaneous sleep, scientists tested whether induced slumber was essential to the formation of long-term memories. In a process called courtship conditioning, male flies were exposed to other males genetically modified to make female sex pheromones.

"The subject fly will initiate courtship because of the female pheromones, but the modified male making those pheromones inevitably reje
'/>"/>

Contact: Michael C. Purdy
purdym@wustl.edu
314-286-0122
Washington University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Obstructive Sleep Apnea in Kids May Have Genetic Cause
2. Sleep HealthCenters to Sponsor North East Sleep Society 2010
3. America's Hidden Pandemic: 100 Million Suffer From Sleep Problems
4. Solutions for Sleep Problems: Harvard's Improving Sleep Special Health Report and New Sleep Apnea Video
5. Behavioral therapy improves sleep and lives of patients with pain
6. Sleep problems and sleepiness increase the risk of motor vehicle accidents in adolescents
7. Severe sleep apnea decreases frequency of nightmare recall
8. Severe Sleep Apnea Has Silver Lining
9. The role of sleep in brain development
10. Sleep More, Lose Weight – Sleeplessness Linked to Obesity
11. National Sleep Awareness Week(R) (March 7-13): How Are You Sleeping?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... The click strand woven bamboo flooring ... the business announces a click strand woven bamboo ... 2015. , Click strand woven bamboo flooring replicates ... well-known brand in the bamboo industry. It promises ... bamboo flooring supplier. , “We are happy to ...
(Date:12/25/2014)... iFitDress.com, the popular online supplier of wedding dresses and special ... black one-shoulder cocktail dresses . In addition, all these ... discounted prices, up to 70% off. , The ... only. You know, we have thousands of frequent callers in ... items can visit our website for more details. The current ...
(Date:12/25/2014)... 2014 Helen Harris’ RP (Retinitis Pigmentosa) ... California after an 8 year battle with breast cancer. ... evening in her home in Woodland Hills California after ... , As the founder and volunteer ... pioneered and championed many of today's greatest breakthroughs in ...
(Date:12/25/2014)... News) -- Overeating is common during the holidays, but there ... expert says. "Don,t arrive at a party hungry. It ... you,ll be attending a party, but deprivation leads to hunger, ... Northern Westchester Hospital in Mount Kisco, N.Y., said in a ... the day and even to have a snack before attending ...
(Date:12/25/2014)... 25, 2014 “ SmileStix ” was featured ... the latest and coolest mobile applications on the iOS, Android, ... host of NewsWatch, conducted the app review and shared with ... personal stickers. , The old saying goes, “A picture says ... words that can describe a single image, because each picture ...
Breaking Medicine News(10 mins):Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2
... publisher of open access journals, is pleased to ... (JCMR) is moving to BioMed Centrals open access ... & Francis. The move from a subscription publisher ... Cardiovascular Magnetic Resonance (SCMR) members and JCMR authors ...
... OCALA, Fla., Dec. 12 Franck,s Compounding Lab ... Pharmacy Services in,Woodruff, Wisconsin. Island Pharmacy owners, Randy ... other personal interests. Selling their,pharmacy to Franck,s Compounding ... ensure the continuance of high quality prescriptions and ...
... and Babies "R" Us to help prepare local moms for the ... ... Dec. 12 With a traditional theme of,pink and blue, local ... Blue Shield hosts a community-wide baby shower today,for local moms-to-be at ...
... found fat mice had harder time fighting gum disease ... people find it harder to fight infections, and a ... new study from Boston University researchers. , In experiments ... , obese mice had less ability to battle gum ...
... antibody,engineering company developing novel antibodies and antibody fragments,based ... that it,has established a Scientific Advisory Board and ... of this advisory body. Members,of f-star,s Scientific Advisory ... College, London, UK, Sir Ravinder Maini is ...
... to six community organizations in ... underserved areas, WOODLAND HILLS, ... a total of $30,000 in end of,year donations to various food banks ... agencies in northern and,southern California to assist vulnerable populations., Blue Cross ...
Cached Medicine News:Health News:Society of Cardiovascular Magnetic Resonance chooses open access 2Health News:Anthem Blue Cross and Blue Shield Celebrates Local Moms-to-Be at Community Baby Shower 2Health News:Anthem Blue Cross and Blue Shield Celebrates Local Moms-to-Be at Community Baby Shower 3Health News:Obesity Weakens Immune Response 2Health News:Antibody Engineering Company f-star Appoints Three Pioneers in Antibody Engineering and Development to its Newly Established Scientific Advisory Board 2Health News:Antibody Engineering Company f-star Appoints Three Pioneers in Antibody Engineering and Development to its Newly Established Scientific Advisory Board 3Health News:Blue Cross of California Gives $30,000 in Holiday Donations to Food Banks Throughout the State 2
(Date:12/24/2014)... 2014 Soligenix, Inc. (OTCQB: SNGX) (Soligenix ... products that address unmet medical needs in the ... that on December 24, 2014 it closed its ... Company raised approximately $2.3 million in gross proceeds ... net proceeds from the offering to fund its ...
(Date:12/24/2014)... and LONDON , December 24, ... industry are expected to grow at an average rate ... of value and volume. Hip, knee and spine surgeries ... while in emerging economies they have a lower penetration. ... challenging the use of composites. Non-metallic orthopedic devices have ...
(Date:12/24/2014)... December 24, 2014 ... Global Disposable Syringe Industry of 178 pages ... business intelligence library. The 2014 ... Industry is a professional and deep research ... overview analysis, the report introduces Disposable Syringe ...
Breaking Medicine Technology:Soligenix Announces Closing of Public Offering of Units 2Soligenix Announces Closing of Public Offering of Units 3Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
... , BOSTON, Oct. 2 Massachusetts General Hospital (MGH) Cancer ... including three Elekta Infinity and one ... management software , will enable the facility to offer ... The three Infinity systems position MGH ...
... Oct. 2 Caraco Pharmaceutical Laboratories, Ltd. (NYSE ... of the previously announced settlement of the legal ... closed an Asset Purchase Agreement ("APA") transaction with ... from Forest,s Inwood line of business. The ANDA ...
Cached Medicine Technology:Massachusetts General Hospital Selects Elekta As New Vendor for Complete Cancer Treatment Solution 2Caraco Pharmaceutical Laboratories, Ltd. Closes Asset Purchase Agreement with Forest Laboratories, Inc. to Settle Lexapro(R) (escitalopram oxalate) ANDA Patent Litigation 2
For use with Slitlamps which have a smaller distance between the eye and the reduction prism than the Haag-Streit 900. Designed to work with argon/YAG Lasers....
... complete image capture and management application that ... leading ophthalmic clinicians, ophthalmic photographers and optometrists ... securely document the eye via the slit ... slit lamps equipped with digital or video ...
... EyeCap SL is the most advanced means ... capture and management system that acquires extremely ... latest technology.Images can be captured directly from ... cameras, as well as any other ophthalmic ...
The best combination with the Haag-Streit 900 Slitlamps. For examination of the entire fundus, the vitreous and the iridocorneal angle. For children up to 4 years of age. 11 mm internal diameter of t...
Medicine Products: