Navigation Links
Sleep duration associated with higher colorectal cancer risk
Date:4/30/2013

A new study is the first to report a significant positive association between long sleep duration and the development of colorectal cancer, especially among individuals who are overweight or snore regularly. The results raise the possibility that obstructive sleep apnea may contribute to cancer risk.

"Our current study adds to the very limited literature regarding the relationship between sleep duration and/or sleep quality and colorectal cancer risk," said lead author Xuehong Zhang, MD, ScD, instructor in the Department of Medicine at Harvard Medical School and associate epidemiologist at Brigham and Women's Hospital in Boston. "The novel observation of increased risk among regular snorers who sleep long raises the possibility that sleep apnea and its attendant intermittent hypoxemia may contribute to cancer risk."

The study, which appears in the May issue of the journal Sleep, utilized data from two prospective cohort studies, the Health Professionals Follow-up Study (HPFS) and the Nurses' Health Study (NHS). A biennial questionnaire is sent to participants in each cohort to collect information on demographics, lifestyle factors and disease endpoints. Participants estimated their total hours of sleep in a 24-hour period and were asked if they snore.

A total of 76,368 women and 30,121 men formed the baseline population for this analysis. At baseline the median age was 53 years for women and 56 years for men. The researchers documented a total of 1,973 incident colorectal cancer cases: 1,264 cases in NHS (1986-2008) and 709 cases in HPFS (1988-2008). In subgroup analyses, men or women who were overweight or who were regular snorers and who reported sleeping 9 hours or more per day had approximately a 1.4 to 2-fold increased risk of developing colorectal cancer compared to overweight or regular snorers with 7 hours of sleep per day.

The American Academy of Sleep Medicine reports that individual sleep needs vary. However, the general recommendation is that most adults should get about seven to eight hours of nightly sleep.

The authors suggest that the association between the self-reported long sleep duration and incident colorectal cancer may be explained by obstructive sleep apnea, which involves repetitive episodes of complete or partial upper airway obstruction occurring during sleep despite an ongoing effort to breathe. The major predisposing factor for obstructive sleep apnea (OSA) is excess body weight, and loud snoring is a common symptom of sleep apnea.

According to the authors, sleep disruption caused by OSA may reduce sleep quality and increase sleepiness, resulting in longer reported sleep durations. Furthermore, intermittent hypoxemia similar to that which occurs in OSA has been shown in animal models to promote tumor growth.

"Future studies should focus on different populations and evaluate to see whether sleep duration and sleep quality is a novel risk factor for colorectal cancer and to understand the mechanisms behind this association," said Zhang.

According to the Centers for Disease Control and Prevention (CDC), colorectal cancer is the third most commonly diagnosed cancer and the second leading cause of cancer deaths in men and women combined in the U.S.


'/>"/>

Contact: Lynn Celmer
lcelmer@aasmnet.org
630-737-9700
American Academy of Sleep Medicine
Source:Eurekalert

Related medicine news :

1. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
2. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
3. Depressed moms behavior may play role in infants sleep problems
4. Depressed Moms May Hinder Babies Sleep
5. Poor Sleep Heightens Ringing Ear Disease Symptoms: Study
6. Adjusting Your Attitude About Chronic Pain May Help You Sleep
7. Excessive sleepiness may be cause of learning, attention and school problems
8. Study: Kids Who Sleep in Parents Bed Less Likely to Be Overweight
9. Sleepwalking in Adults More Common Than Thought
10. Pediatric epilepsy impacts sleep for the child and parents
11. Parents Often Lose Sleep Over Childs Epilepsy, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified ... be personalized through a fitness app. The fitness app plans to fix the two major ... only offer a one size fits all type program , They don’t eliminate ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Austin residents ... the American College of Mohs Surgery and to Dr. Russell Peckham for medical and ... highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 Dehaier Medical Systems Ltd. (NASDAQ: ... markets and sells medical devices and wearable sleep respiratory ... strategic cooperation agreement with Hongyuan Supply Chain Management Co., ... June 20, 2016, to develop Dehaier,s new Internet medical ... Dehaier will leverage Hongyuan Supply Chain,s sales platform to ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... --  Pulmatrix, Inc ., (NASDAQ: PULM ), ... today that it was added to the Russell Microcap ... set of U.S. and global equity indexes on June ... for Pulmatrix," said Chief Executive Officer Robert Clarke ... in developing drugs for crucial unmet medical needs, and ...
Breaking Medicine Technology: