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Sleep apnea tied to diabetes in large study
Date:6/5/2014

during rapid eye movement sleep and measures of the physiologic consequences of OSA, including oxygen desaturation, sleep deprivation and activation of the sympathetic nervous system, as indicated by a higher mean heart rate during sleep.

"After adjusting for other potential causes, we were able to demonstrate a significant association between OSA severity and the risk of developing diabetes," said Dr. Kendzerska. "Our findings that prolonged oxygen desaturation, shorter sleep time and higher heart rate were associated with diabetes are consistent with the pathophysiological mechanisms thought to underlie the relationship between OSA and diabetes."

The study had a few limitations, including a lack of data on some potential confounders, including family history of diabetes and race, and the possible misclassification of some subjects due to the limitations of the administrative health data used.

"The OSA-related predictors of increased diabetes risk that we found in our study may allow for early preventative interventions in these patients," said Dr. Kendzerska.


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Contact: Nathaniel Dunford
ndunford@thoracic.org
American Thoracic Society
Source:Eurekalert

Page: 1 2

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