Navigation Links
Sleep May Be Essential for Long-Term Memory
Date:6/24/2009

Researchers demonstrate that slumber key to storing memories

WEDNESDAY, June 24 (HealthDay News) -- Researchers at MIT have confirmed that sleep is essential for long-term storage of memories.

Their study showed that mice unable to "replay" their awake experiences while asleep remember them less well than mice who can perform this function. Scientists from the RIKEN-MIT Center for Neural Circuit Genetics at MITs Picower Institute for Learning and Memory report their findings in the June 24 issue of Neuron.

"Our work demonstrates the molecular link between post-experience sleep and the establishment of long-term memory of that experience," study author Susumu Tonegawa, Picower Professor of Biology and Neuroscience, said in a school news release. "Ours is the first study to demonstrate this link between memory replay and memory consolidation. The sleeping brain must replay experiences like video clips before they are transformed from short-term into long-term memories."

Researchers tested their theories by implanting electrodes in the brains of mice that were fed a special diet to disrupt their trisynaptic circuits. These circuits, found in the hippocampus, are now confirmed to play a crucial role in processing memories before they move on to other regions for storage.

While they were awake and running in a maze, the mice formed cells that fired in recognition of their newly learned task -- negotiating the maze. Those cells fired in similar sequences during their post-run sleep. Mice whose trisynaptic circuits functioned properly during sleep remembered the maze longer than those whose trisynaptic circuits were disabled, researchers reported.

"Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa.

More information

Learn more about this and other studies at The Picower Institute.



-- Peter West



SOURCE: MIT News Office, news release, June 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Time to Set Kids Back-to-School Sleep Clocks
2. AASM encourages those student-athletes at risk for developing osa to visit a sleep clinic
3. Sleepless Kids Are Troubled Kids
4. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
5. Work time is the largest influence to the duration of a persons sleep
6. Passive smoking increases sleep disturbance among pregnant women
7. Minorities more likely to have sleep durations associated with increased mortality
8. Lack of sleep among new school-goers leads to behavioral, cognitive problems
9. Work Time Predicts Sleep Time
10. Nicotine in breast milk disrupts infants sleep patterns
11. Pain patients at risk for sleep apnea
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sleep May Be Essential for Long-Term Memory
(Date:3/22/2017)... Bolton, MA San Antonio, TX (PRWEB) , ... ... ... audited and ISO certified medical imaging core lab with extensive therapeutic experience and ... awarded a multi-year phase II immuno-oncology clinical trial for the treatment of non-small ...
(Date:3/22/2017)... (PRWEB) , ... March 22, 2017 , ... ... protection assistance and financial consultations to families and business owners in the greater ... for the local American Cancer Society Relay For Life event. , Each year, ...
(Date:3/22/2017)... TX (PRWEB) , ... March 22, 2017 , ... ... insurance consultation, financial planning, and related services to communities across eastern Texas, is ... the goal of providing meals to hungry children and adults. , Consistently ...
(Date:3/22/2017)... ... March 22, 2017 , ... Schneider Insurance and Financial, ... business owners throughout the Yellowstone Valley region, is launching a charity event aimed at ... botanical garden in all of Montana State, and is home to a broad variety ...
(Date:3/22/2017)... ... ... Chris Humphrey Insurance Agency, a North Carolina firm offering asset protection services ... is initiating a charity event to raise support for five year old Dillyn, a ... a Friday evening in September 2014. At the time, Dillyn was only four years ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... , March 22, 2017 FinancialBuzz.com News ... According to ... was worth an estimated $6.6 billion in 2016, and is projected ... or reaching more than $24 billion by 2025. The medical cannabis ... growing from $4.7 billion in 2016, to an estimated $13.3 billion ...
(Date:3/22/2017)... 2017 EMD Serono, the biopharmaceutical business of Merck ... and Canada , today announced two new ... session at the 65 th Annual Pacific Coast Reproductive ... on March 24 th .   The results ... collected from July 2009 to December 2015 containing data from ...
(Date:3/22/2017)... MarketNewsUpdates.com News Commentary  ... As ... oil continues to rise in popularity with consumers, Cannabis ... enhancing production through acquiring innovative assets and other plant ... include: Future Farm Technologies Inc (OTC: FFRMF) (CSE: FFT.CN), mCig, ...
Breaking Medicine Technology: