Navigation Links
Sleep May Be Essential for Long-Term Memory
Date:6/24/2009

Researchers demonstrate that slumber key to storing memories

WEDNESDAY, June 24 (HealthDay News) -- Researchers at MIT have confirmed that sleep is essential for long-term storage of memories.

Their study showed that mice unable to "replay" their awake experiences while asleep remember them less well than mice who can perform this function. Scientists from the RIKEN-MIT Center for Neural Circuit Genetics at MITs Picower Institute for Learning and Memory report their findings in the June 24 issue of Neuron.

"Our work demonstrates the molecular link between post-experience sleep and the establishment of long-term memory of that experience," study author Susumu Tonegawa, Picower Professor of Biology and Neuroscience, said in a school news release. "Ours is the first study to demonstrate this link between memory replay and memory consolidation. The sleeping brain must replay experiences like video clips before they are transformed from short-term into long-term memories."

Researchers tested their theories by implanting electrodes in the brains of mice that were fed a special diet to disrupt their trisynaptic circuits. These circuits, found in the hippocampus, are now confirmed to play a crucial role in processing memories before they move on to other regions for storage.

While they were awake and running in a maze, the mice formed cells that fired in recognition of their newly learned task -- negotiating the maze. Those cells fired in similar sequences during their post-run sleep. Mice whose trisynaptic circuits functioned properly during sleep remembered the maze longer than those whose trisynaptic circuits were disabled, researchers reported.

"Our conclusion is that the trisynaptic pathway-mediated replay of the hippocampal memory sequence during sleep plays a crucial role in the formation of a long-term memory," said Tonegawa.

More information

Learn more about this and other studies at The Picower Institute.



-- Peter West



SOURCE: MIT News Office, news release, June 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Time to Set Kids Back-to-School Sleep Clocks
2. AASM encourages those student-athletes at risk for developing osa to visit a sleep clinic
3. Sleepless Kids Are Troubled Kids
4. Jefferson specialists studying innovative surgery for effectively treating sleep apnea
5. Work time is the largest influence to the duration of a persons sleep
6. Passive smoking increases sleep disturbance among pregnant women
7. Minorities more likely to have sleep durations associated with increased mortality
8. Lack of sleep among new school-goers leads to behavioral, cognitive problems
9. Work Time Predicts Sleep Time
10. Nicotine in breast milk disrupts infants sleep patterns
11. Pain patients at risk for sleep apnea
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Sleep May Be Essential for Long-Term Memory
(Date:5/29/2017)... ... May 29, 2017 , ... Thomas Dickerson, ... is the new president of the Board of Directors for the Radiology ... administrators. He succeeds outgoing Board President Jim Hamilton, MHA, CMM, FRBMA, an administrator ...
(Date:5/28/2017)... ... 2017 , ... HYPERAMS, LLC announced it will perform the inventory ... Lima, Ohio. The sale began this week and the inventory is expected to sell ... uniforms, and medical accessories, including blood pressure cuffs, stethoscopes, CPR masks, as well as ...
(Date:5/27/2017)... Angeles, California (PRWEB) , ... May 26, 2017 , ... ... senior citizens who visit a doctor for colds or respiratory issues that are not ... that excessive time pressure on doctors may be largely responsible for the problem both ...
(Date:5/27/2017)... (PRWEB) , ... May 27, 2017 , ... Most us ... concern, but a new study from the Osteoarthritis Initiative shows that certain ... knee osteoarthritis. Knowing this in advance may give doctors the opportunity to treat patients ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... ... to announce a new educational seminar to focus on current legislative activity and ... seminar will begin at 1 p.m. Sunday, Sept. 10, and will continue through ...
Breaking Medicine News(10 mins):
(Date:5/12/2017)... , May 12, 2017  The China and Canada ... technology that consumes less water, energy and detergent, and features a ... product LaughingU, a shoebox-sized washing machine that washes and sanitizes women,s ... ... LaughingU, is compact, and does not require an external water inlet. ...
(Date:5/10/2017)... MARLBOROUGH, Mass., May 10, 2017 Hologic, Inc. ... financial results for the fiscal second quarter ended April ... (EPS) of $1.84 increased 666.7% compared to the prior ... business resulted in a significant gain, while non-GAAP diluted ... increased 3.2%, or 3.8% in constant currency terms.  Excluding ...
(Date:5/10/2017)... , May 10, 2017  The Corporate ... or employees of sleep therapy clinics to call ... sleep therapy clinic is involved in a substantial ... interested in hearing from an employee of a ... in a kickback scheme to provide medical practice groups ...
Breaking Medicine Technology: