Navigation Links
Sleep Disorder Linked to Neurodegenerative Conditions
Date:4/15/2008

Rapid eye movement disorder can involve anxiety, low attention levels and Parkinson's

TUESDAY, April 15 (HealthDay News) -- Rapid eye movement (REM) sleep behavior disorder -- a condition in which people act out often violent and disturbing dreams -- is associated with anxiety, apathy, lower levels of attention and executive functioning, and symptoms of Parkinson's disease, according to three new studies.

The acting out in people with REM sleep behavior disorder (RBD) occurs because they don't experience the normal muscle paralysis in REM sleep, the stage of sleep when people dream. RBD occurs in about 0.5 percent of the population, most frequently in older males.

"Previous studies have shown that some patients with RBD subsequently develop dementia and/or parkinsonism, which typically reflects a neurodegenerative disorder such as Lewy body dementia or Parkinson's disease," Mayo neurologist and study author Dr. Bradley Boeve said in a prepared statement.

"Our knowledge on the RBD-neurodegenerative disease association is largely based on studies focused on single patients, or small groups of patients, with RBD. There are very few studies that have been carried out on RBD on a large scale. Plus, we currently aren't able to identify which patients with RBD will later develop other features of a neurodegenerative disease and which patients with RBD will not."

In an effort to learn more, Boeve and his colleagues studied 765 people, aged 70 to 89, including about 60 with probable RBD.

Of those with probable RBD, 21 percent had anxiety and 11.5 percent had apathy, compared with 8 percent and 4 percent, respectively, among those without the condition. The participants with probable RBD also had significantly lower scores on neuropsychological measures of attention and executive functioning, such as concentration, decision making, and higher order problem-solving. The researchers also found that 1.8 percent of participants had both RBD and parkinsonism.

The study was expected to be presented Tuesday at the American Academy of Neurology annual meeting in Chicago.

"There is currently no treatment to delay the onset or prevent dementia or parkinsonism in patients with RBD who are destined to develop these neurologic problems in the future," Boeve said. "Our ultimate goal is to use therapies that would delay the onset or prevent these problems from ever developing in patients who have a form of RBD that reflects an evolving neurodegenerative disease. However, much more research is needed to get to that point."

More information

We Move has more about Parkinson's disease.



-- Robert Preidt



SOURCE: American Academy of Neurology, news release, April 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. No difference in sleep of OSA patients studied in a hospital vs. a hotel-based sleep center
2. JCSM: A high frequency of sleep-related breathing disorders in hospitalized patients
3. Study sheds light on link between sleep disorder, behavior issues in kids
4. Sleep, baby, sleep: parents behavior has direct impact on children’s slumber
5. Too Little Sleep Leads to Too Much Weight for Kids
6. U of T research finds glycine could be key to REM Sleep Behavior Disorder
7. Dr. Tracy Rupp wins the National Sleep Foundation Young Investigator Award
8. Targeting aggressive breast cancers by putting them to sleep
9. Sleep Deprivation Helps Spot Sleepwalkers
10. Lack of Sleep Hurts Womens Hearts Most
11. Molecular biology of sleep apnea could lead to new treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2017)... ... ... Month and the focus is on prostate cancer. Second only to skin cancer, prostate ... common cause of cancer related death today; lung cancer remains in the number one spot. ... during his lifetime. Those at highest risk are men who have a family ...
(Date:6/24/2017)... ... ... Doorknobs are for convenience, deadbolts are for security. , There are many ... an alarm system installed. But unless there is a working deadbolt lock that is ... Premier Locksmith in Killeen, TX says: “In the majority of home burglaries, intruders use ...
(Date:6/23/2017)... ... June 24, 2017 , ... Studies show evidence that carotenoids and antioxidants derived ... loss in these patients. , But how often do ophthalmologists and optometrists in Sweden ... at risk of or with early symptoms of AMD? A study published recently ...
(Date:6/23/2017)... ... ... Goodcents Deli Fresh Subs today announced the opening of a new restaurant ... Topeka, Kan. 66604 (near 21st and Gage). It is owned and operated by long-time ... in the Topeka and Bonner Springs, Kan. area. , “Goodcents has such a ...
(Date:6/23/2017)... ... June 23, 2017 , ... MD Now Urgent ... is MD Now’s 28th facility overall and marks the urgent care center's eighth location ... mile North of The Falls shopping mall. The new clinic offers a wide array ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 7, 2017  Novavax, Inc., (Nasdaq: NVAX ) ... 2 trials of its RSV F protein recombinant nanoparticle vaccine ... have been published in the journal Vaccine ... in prior scientific conferences). The Company previously announced top ... is developing the RSV F Vaccine with the goal of ...
(Date:6/2/2017)... , June 2, 2017  NxStage Medical, Inc. (Nasdaq:  NXTM), a ... today announced new findings demonstrating positive biochemical outcomes related ... System One™. The data will be presented at the ... Madrid, Spain . The ... Home Dialysis Network in Europe ...
(Date:5/29/2017)... -- Cellect Biotechnology Ltd. (NASDAQ: APOP ; TASE: APOP), ... selection of stem cells, today provided a corporate update ... March 31 st , 2017. "We ... quarter of 2017," said Dr. Shai Yarkoni, Chief Executive ... of the first blood cancer patient in the recently ...
Breaking Medicine Technology: