Navigation Links
Sleep Disorder Linked to Neurodegenerative Conditions
Date:4/15/2008

Rapid eye movement disorder can involve anxiety, low attention levels and Parkinson's

TUESDAY, April 15 (HealthDay News) -- Rapid eye movement (REM) sleep behavior disorder -- a condition in which people act out often violent and disturbing dreams -- is associated with anxiety, apathy, lower levels of attention and executive functioning, and symptoms of Parkinson's disease, according to three new studies.

The acting out in people with REM sleep behavior disorder (RBD) occurs because they don't experience the normal muscle paralysis in REM sleep, the stage of sleep when people dream. RBD occurs in about 0.5 percent of the population, most frequently in older males.

"Previous studies have shown that some patients with RBD subsequently develop dementia and/or parkinsonism, which typically reflects a neurodegenerative disorder such as Lewy body dementia or Parkinson's disease," Mayo neurologist and study author Dr. Bradley Boeve said in a prepared statement.

"Our knowledge on the RBD-neurodegenerative disease association is largely based on studies focused on single patients, or small groups of patients, with RBD. There are very few studies that have been carried out on RBD on a large scale. Plus, we currently aren't able to identify which patients with RBD will later develop other features of a neurodegenerative disease and which patients with RBD will not."

In an effort to learn more, Boeve and his colleagues studied 765 people, aged 70 to 89, including about 60 with probable RBD.

Of those with probable RBD, 21 percent had anxiety and 11.5 percent had apathy, compared with 8 percent and 4 percent, respectively, among those without the condition. The participants with probable RBD also had significantly lower scores on neuropsychological measures of attention and executive functioning, such as concentration, decision making, and higher order problem-solving. The researchers also found that 1.8 percent of participants had both RBD and parkinsonism.

The study was expected to be presented Tuesday at the American Academy of Neurology annual meeting in Chicago.

"There is currently no treatment to delay the onset or prevent dementia or parkinsonism in patients with RBD who are destined to develop these neurologic problems in the future," Boeve said. "Our ultimate goal is to use therapies that would delay the onset or prevent these problems from ever developing in patients who have a form of RBD that reflects an evolving neurodegenerative disease. However, much more research is needed to get to that point."

More information

We Move has more about Parkinson's disease.



-- Robert Preidt



SOURCE: American Academy of Neurology, news release, April 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. No difference in sleep of OSA patients studied in a hospital vs. a hotel-based sleep center
2. JCSM: A high frequency of sleep-related breathing disorders in hospitalized patients
3. Study sheds light on link between sleep disorder, behavior issues in kids
4. Sleep, baby, sleep: parents behavior has direct impact on children’s slumber
5. Too Little Sleep Leads to Too Much Weight for Kids
6. U of T research finds glycine could be key to REM Sleep Behavior Disorder
7. Dr. Tracy Rupp wins the National Sleep Foundation Young Investigator Award
8. Targeting aggressive breast cancers by putting them to sleep
9. Sleep Deprivation Helps Spot Sleepwalkers
10. Lack of Sleep Hurts Womens Hearts Most
11. Molecular biology of sleep apnea could lead to new treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/17/2017)... , ... August 17, 2017 , ... Inc. Magazine Unveils ... at No. 132 with Three-Year Sales Growth of 3,004.8% , NEW YORK, August 16, ... Inc. 5000, the most prestigious ranking of the nation's fastest-growing private companies. The list ...
(Date:8/17/2017)... , ... August 17, 2017 , ... ... Employers , an international competition, were announced today. The awards recognize the world’s ... suppliers who help to create and drive great places to work. , A ...
(Date:8/16/2017)... ... August 16, 2017 , ... Blue Health Intelligence (BHI) ... President, Chief Medical Officer. Dr. Spiro brings over 30 years of clinical, healthcare IT, ... for BHI’s cutting-edge analytics solutions. , “I am thrilled to welcome Dr. Spiro ...
(Date:8/16/2017)... Atlanta, GA (PRWEB) , ... August 16, 2017 , ... ... the new Inc. 5000. The company ranked #4429 on the newly released, 36th annual ... The list represents a unique look at the most successful companies within the American ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... their recently launched community enrichment program. Partnering once again with Boys & Girls ... competition to help find the area’s very own American Idol. With all proceeds ...
Breaking Medicine News(10 mins):
(Date:8/2/2017)... AROMAS, Calif. , Aug. 2, 2017 /PRNewswire/ ... by Continental Who,s Who as a Pinnacle Lifetime ... currently the Key Account Manager at Turing Pharmaceuticals, ... communications, negotiations, troubleshooting and relationship building.                ... has more than 25 years of experience ...
(Date:7/31/2017)... FLINT, Mich. , July 31, 2017  Diplomat Pharmacy, ... companies in southeast Michigan by ... feature ranks private and public companies by three-year revenue growth. ... To view the complete list, ... Crain,s Fast 50 is an incredible triumph," said Phil ...
(Date:7/27/2017)... -- Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) today reported ... The Company reported second quarter net sales of $1.954 ... period, and an increase of 2.1% on a constant ... from the LDR Holding Corporation acquisition, second quarter 2017 ... or 0.3% on a constant currency basis. ...
Breaking Medicine Technology: