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Skin deep: Fruit flies reveal clues to wound healing in humans
Date:4/5/2013

hink one amazing application of our studies may be to build a better bandage containing compounds to promote wound healing," said Dr. Juarez.

"Perhaps our results can be translated to existing human therapies by incorporating specific, regulated serine proteases and antimicrobial peptides at the sites of diabetic ulcers or skin grafts for more efficient wound healing," Ms. Patterson said.

Ms. Patterson also suggests that this fly research may lead to broader discoveries regarding human skin diseases. Further examination of the roles of serine proteases in wound healing may inform treatment for chronic skin diseases, including psoriasis, severe dry skin, and eczema where levels of these enzymes are known to be abnormal.

Session Title: Immunity and Pathogenesis
Program: #43 -- Date and Time: Friday, April 5, 2013; 9:30-9:45 a.m.
Location: Marriott Wardman Park, Marriott Ballroom Salon 3, Lobby Level
Intersection of Drosophila innate immunity and epidermal wound response in the serine proteolytic pathway. Michelle T. Juarez, Rachel A. Patterson, William McGinnis.
University of California, San Diego, La Jolla, CA.


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Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-634-7302
Genetics Society of America
Source:Eurekalert

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