Navigation Links
Skin cancer risk may have driven evolution of black skin
Date:2/25/2014

Early humans may have evolved black skin to protect against a very high risk of dying from ultraviolet light (UV)-induced skin cancer, a new analysis concludes.

Skin cancer has usually been rejected as the most likely selective pressure for the development of black skin because of a belief that it is only rarely fatal at ages young enough to affect reproduction.

But a new paper, published in Proceedings of the Royal Society B, cites evidence that black people with albinism from parts of Africa with the highest UV radiation exposure, and where humans first evolved, almost all die of skin cancer at a young age.

The paper, by Professor Mel Greaves at The Institute of Cancer Research, London, cites studies showing that 80 per cent or more of people with albinism from African equatorial countries such as Tanzania and Nigeria develop lethal skin cancers before the age of 30.

Albinism is also linked to skin cancer in indigenous populations of other tropical countries with high, year-round UV exposure such as Panama.

Professor Greaves argues that the fact that people with albinism, which is caused by genetic changes that prevent the production of melanin, develop cancer at reproductive ages is indirect but persuasive evidence that early, pale-skinned humans were under strong evolutionary pressure to develop melanin-rich skin in order to avoid lethal skin cancer.

Genetic evidence suggests that the evolution of skin rich in eumelanin, which is brown-black in colour, occurred in early humans between 1.2 and 1.8 million years ago in the East African Savannah. Early humans having lost most of their body hair (probably to facilitate heat loss) probably had pale skin containing pheomelanin - like our nearest surviving relatives, chimpanzees. Pheomelanin, characteristic of white skin, is red-yellow and packaged into smaller stores under the skin than eumelanin, characteristic of black skin. Eumelanin provides a much
'/>"/>

Contact: Henry French
henry.french@icr.ac.uk
020-715-35312
Institute of Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn researchers show nuclear stiffness keeps stem cells and cancer cells in place
2. CWRU researchers find byproducts of bacteria-causing gum disease incite oral cancer growth
3. Building a better mouse model to understand pancreatic cancer
4. The only top 10 cancer where survival rates are falling
5. A paper diagnostic for cancer
6. Uninsured adolescents and young adults more likely to be diagnosed with advanced cancer
7. Dismantling pancreas cancers armor
8. Feasible, safe to limit radiation to major salivary glands in head and neck cancer patients
9. Patients with oropharyngeal cancer report quality of voice and speech affected post-treatment
10. Unilateral radiation therapy for advanced stage tonsil cancer results in favorable outcomes
11. Hypnosis therapy shown to decrease fatigue levels in breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Deer Path of Huntley -- a BMA affordable ... from 3 p.m. to 4 p.m. on Feb. 13. , The ... serves adults with physical disabilities between the ages of 22 and ... games and sweetheart-themed karaoke. , For more information about the event ...
(Date:1/22/2015)... Va. (PRWEB) January 22, 2015 Liberty University ... Counseling (M.A.) program from the Council for Accreditation ... program, part of Liberty’s Center for Counseling & Family ... founding dean of the university’s new School of Behavioral Sciences. ...
(Date:1/22/2015)... West Hollywood, California (PRWEB) January 22, 2015 The ... 22, 2015 at 10 a.m., to commemorate the 42nd anniversary of ... the United States. , “It’s been 42 years since the Roe ... to choose is still as present as ever,” said City of ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release of ... kids with cancer. The Chemo Duck App, available on iTunes for ... games to help children of all ages living with cancer adjust ... kids entertained, educated and at ease while waiting for clinic visits ...
(Date:1/22/2015)... 2015 VogueQueen is a seasoned and trusted ... many designers are thrilled to have it lead the wedding ... new collection of prom dresses for the global market. , ... strategic vision and he focuses on continuing the goal of ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2
... CAMBRIDGE, Mass., Oct. 28 Biopure Corporation,(Nasdaq: ... a notice from the,Medicines Control Council (MCC) of ... of Hemopure [hemoglobin glutamer-250,(bovine)], Biopure,s oxygen therapeutic for ... intends to appeal the decision promptly and,expects to ...
... Periodontal disease rises as the joint ailment worsens, research ... arthritis (RA) may increase the risk of gum disease, ... a link between RA and periodontal disease, a condition ... teeth from the gums, loss of bony support, and ...
... NEWPORT BEACH, Calif., Oct. 28 Nationwide,Health Properties, Inc. ... of,Directors declared a $0.44 per share dividend on our ... to shareholders of record on November 14, 2008., ... per share,dividend on our Series B cumulative convertible preferred ...
... Oct. 28 IRIDEX,Corporation (Nasdaq: IRIX ) today ... results after the market closes on Tuesday, November,4, 2008. ... a,conference call with the investment community at 5:00 p.m. ... results of the quarter and other,business developments., Interested ...
... (TSX: RBM, OTCBB: RPBIF) (the "Company") today announced ... financing announced on October,14, 2008 and amended on ... The closing involved a brokered and non-brokered private ... for each unit. Each unit consisted,of one common ...
... 26, 2008) A single administration of a novel, nasally ... were more than 20 times higher than those generated ... to a study by NanoBio Corporation. The new vaccine ... this effect. , Results of the study are being ...
Cached Medicine News:Health News:Agency Takes Adverse Decision to Biopure's Product Registration in South Africa 2Health News:Agency Takes Adverse Decision to Biopure's Product Registration in South Africa 3Health News:Rheumatoid Arthritis May Harm Gums 2Health News:NHP Declares Quarterly Cash Dividends on Common Stock and Series B Preferred Stock 2Health News:NHP Declares Quarterly Cash Dividends on Common Stock and Series B Preferred Stock 3Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 2Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 3Health News:Response Biomedical Completes Initial Closing of an expected $5.0 Million Financing 4Health News:New intranasal influenza vaccine triggers robust immunity with significantly less antigen 2
(Date:1/23/2015)... Jan. 23, 2015  Pete Rose, baseball,s all-time hits leader, is ... pain reliever Myoflex, Ducere Pharma has announced. "Pete,s ... excited to have him on board with Myoflex," said Ducere ... a legendary player who is known across all generations. The ...
(Date:1/23/2015)... MERIDIAN, Idaho , Jan. 23, 2015  Now available ... Patent No. 7,849,611) support that prevents ankle sprains by ... a brace, it fits securely around the outside of ... ankle mobility & comfort while still offering protection against ...
(Date:1/23/2015)... N.Y. , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. ... its Phase I trial of Lixte,s lead compound, LB‑100, is ... John S. Kovach , M.D., the founder ... planned to be completed at a single site. Accrual of ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... Cymetrix, a leader in providing healthcare organizations ... an alliance with Siemens Healthcare for financial system ... Cymetrix will assist in the transition of select ... to Siemens Soarian®. Cymetrix,s system conversion solution preserves ...
... HORSHAM, Pa., Dec. 7, 2010 Topaz Pharmaceuticals Inc., ... completion of two Phase 3 clinical trials that studied ... treatment for head lice. These trials were conducted according ... Food and Drug Administration (FDA). "Parents and ...
Cached Medicine Technology:Cymetrix Forms Alliance With Siemens Healthcare for System Conversion Support 2Topaz Pharmaceuticals Announces Completion of Pivotal Phase 3 Trials of Ivermectin Topical Cream 2Topaz Pharmaceuticals Announces Completion of Pivotal Phase 3 Trials of Ivermectin Topical Cream 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: