Navigation Links
Skin cancer risk may have driven evolution of black skin
Date:2/25/2014

Early humans may have evolved black skin to protect against a very high risk of dying from ultraviolet light (UV)-induced skin cancer, a new analysis concludes.

Skin cancer has usually been rejected as the most likely selective pressure for the development of black skin because of a belief that it is only rarely fatal at ages young enough to affect reproduction.

But a new paper, published in Proceedings of the Royal Society B, cites evidence that black people with albinism from parts of Africa with the highest UV radiation exposure, and where humans first evolved, almost all die of skin cancer at a young age.

The paper, by Professor Mel Greaves at The Institute of Cancer Research, London, cites studies showing that 80 per cent or more of people with albinism from African equatorial countries such as Tanzania and Nigeria develop lethal skin cancers before the age of 30.

Albinism is also linked to skin cancer in indigenous populations of other tropical countries with high, year-round UV exposure such as Panama.

Professor Greaves argues that the fact that people with albinism, which is caused by genetic changes that prevent the production of melanin, develop cancer at reproductive ages is indirect but persuasive evidence that early, pale-skinned humans were under strong evolutionary pressure to develop melanin-rich skin in order to avoid lethal skin cancer.

Genetic evidence suggests that the evolution of skin rich in eumelanin, which is brown-black in colour, occurred in early humans between 1.2 and 1.8 million years ago in the East African Savannah. Early humans having lost most of their body hair (probably to facilitate heat loss) probably had pale skin containing pheomelanin - like our nearest surviving relatives, chimpanzees. Pheomelanin, characteristic of white skin, is red-yellow and packaged into smaller stores under the skin than eumelanin, characteristic of black skin. Eumelanin provides a much
'/>"/>

Contact: Henry French
henry.french@icr.ac.uk
020-715-35312
Institute of Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Penn researchers show nuclear stiffness keeps stem cells and cancer cells in place
2. CWRU researchers find byproducts of bacteria-causing gum disease incite oral cancer growth
3. Building a better mouse model to understand pancreatic cancer
4. The only top 10 cancer where survival rates are falling
5. A paper diagnostic for cancer
6. Uninsured adolescents and young adults more likely to be diagnosed with advanced cancer
7. Dismantling pancreas cancers armor
8. Feasible, safe to limit radiation to major salivary glands in head and neck cancer patients
9. Patients with oropharyngeal cancer report quality of voice and speech affected post-treatment
10. Unilateral radiation therapy for advanced stage tonsil cancer results in favorable outcomes
11. Hypnosis therapy shown to decrease fatigue levels in breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... July 30, 2014 Good Neighbor ... in an upcoming episode of Innovations with Ed ... Channel. Dates and show times TBA. , In ... Neighbor Community Services’ vision to redefine the traditional ... and dynamic services. Through passion, innovation, determination, excellence, ...
(Date:7/30/2014)... WEDNESDAY, July 30, 2014 (HealthDay News) -- It can happen ... television, dresser or computer monitor and gets critically injured ... of a young child should look around their homes and ... a child. Imagining it is better than it becoming a ... Emergency Physicians, said in a college news release. Between ...
(Date:7/30/2014)... as well as evolutionary changes in a living organismhad ... throughout the genome. , However, recent studies have shown ... mutations that arise simultaneously and in close proximity to ... found in regions where chromosomal rearrangements take place. , ... , may one day lead to new cancer therapies, ...
(Date:7/30/2014)... July 30, 2014 Visitors to our ... over $8,500 to ensure its protection. Bob Kiesendahl, one ... check to the Delaware Highlands Conservancy for donations collected ... small $2-per-stay donations add up fast, as visitors welcome ... Upper Delaware River Region. , The Kiesendahl family has ...
(Date:7/30/2014)... 2014) The phrase "we caught it early" is possibly ... midst of a cancer diagnosis. Combating cancer in its ... certain part of the body, gives patients the best ... colon, prostate and other forms of cancer are touted ... providers recommend cancer screenings as a precautionary measure, especially ...
Breaking Medicine News(10 mins):Health News:Good Neighbor Community Services to be Featured in an Upcoming Episode of Innovations With Ed Begley, Jr. 2Health News:Tip-Over Furniture Can Kill Kids 2Health News:Biologists describe mechanism promoting multiple DNA mutations 2Health News:Pocono Mountain Resort Guests Contribute Over $8500 to Protect Land in 6 Short Months 2Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 2Health News:UK psychologist creates patient tool to assist with lung cancer screening decision 3
... July 8 Fate Therapeutics, Inc. ... research on small molecule modulators of the Wnt pathway ... International Society for Stem Cell Research (ISSCR) in Barcelona, ... selected Wnt activators induce the differentiation of mesenchymal stem ...
... ... a name change to Freedom Disability and has expanded its operations into a new corporate ... growth of the business, bringing hundreds of new jobs to the state. , ... Shelton, CT (PRWEB) July 8, 2009 -- ...
... , HUNTINGTON BEACH, Calif., July 8 "You are what you ... what you drink may be as important as what you eat ... and many others, according to Dr. Cheryle Hart, medical advisor for ... . , , One study referred ...
... ... according to Ed Sinson, On-line Forum and Social Networking Representative. , ... Irvine, Calif. (Vocus) July 8, 2009 ... according to Ed Sinson, On-line Forum and Social Networking Representative. , , ,"We ...
... ... Parts Washers are growing in popularity. These parts washers are cost effective and quick ... economic climate. , ... (Vocus) July 8, 2009 -- Midbrook, a Jackson, MI based manufacturer of industrial parts ...
... created using embryonic stem cells for the first time in ... understanding of the causes of infertility. Researchers led ... England Stem Cell Institute (NESCI) have developed a new technique ... the laboratory. The work is published today (8th ...
Cached Medicine News:Health News:Fate Therapeutics to Present Data on Stimulation of Osteogenic Activity Using Small Molecule Modulators of Wnt Pathway 2Health News:National Social Security Disability Advocacy Firm Changes Name to "Freedom Disability" and Acquires 22,000 Square Foot Corporate Headquarters in Shelton, CT 2Health News:National Social Security Disability Advocacy Firm Changes Name to "Freedom Disability" and Acquires 22,000 Square Foot Corporate Headquarters in Shelton, CT 3Health News:Latest Studies Show 'Junk Drinks' Pose as Many Health Threats as 'Junk Food' According to AquaHydrate Medical Advisor 2Health News:Latest Studies Show 'Junk Drinks' Pose as Many Health Threats as 'Junk Food' According to AquaHydrate Medical Advisor 3Health News:Latest Studies Show 'Junk Drinks' Pose as Many Health Threats as 'Junk Food' According to AquaHydrate Medical Advisor 4Health News:Bariatric Advantage Participates in Social Networks 2Health News:Refurbished and Used Industrial Parts Washers Grow in Popularity 2Health News:Human sperm created from embryonic stem cells 2
(Date:7/30/2014)... ARBOR, Mich. , July 30, 2014 Advanced ... first quarter (ending June 27, 2014) financial results on Monday, ... will be released after the close of the market and ... discuss the results at 4:30 p.m. EDT on the same ... Richard Kurtz (CEO and Director), Rob Risser ...
(Date:7/30/2014)... , July 30, 2014 In conjunction with ... 2014 financial results press release, you are invited to ... live over the internet on Thursday, August 7, 2014 ... A live audio webcast of the presentation ... http://www.durect.com and clicking "Investor Relations."  If you are ...
(Date:7/30/2014)... July 30, 2014 Research and Markets has ... - Forecasts to 2019" report to their offering. ... estimated to grow at a lower CAGR in developed countries; however, ... as China , India , ... The growth of the hematology analyzers and reagents market ...
Breaking Medicine Technology:Advanced Photonix to Webcast Fiscal 2015 First Quarter Earnings 2DURECT Corporation Invites You to Join its Second Quarter 2014 Earnings Conference Call 2Hematology Analyzers & Reagents Market - Forecasts to 2019 2
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Series I Small Joint Arthroscopy Hand Instruments feature small yet durable instruments specifically designed for small joint arthroscopy. They are available in a variety of low profile styles: strai...
Low-profile, hand-held instrument....
Low-profile, hand-held instrument....
Medicine Products: