Navigation Links
Skin Cells Used to Create Heart Valve for Growing Kids
Date:9/3/2014

WEDNESDAY, Sept. 3, 2014 (HealthDay News) -- While artificial heart valves have long been available to adults, making permanent valves for children has been challenging because kids' bodies keep growing.

But researchers say they've found a way around that, using a child's skin cells to make a new pulmonary valve for the youngster's heart to replace a faulty one.

Using a child's own skin cells to create the new valve reduces the risk of rejection, the researchers explained, and means the valve can grow with the patient -- reducing the need for future valve replacements.

The findings appear in the September issue of the Annals of Thoracic Surgery.

"Current valve replacements cannot grow with patients as they age, but the use of a patient-specific pulmonary valve would introduce a 'living' valvular construct that should grow with the patient," lead author David Simpson, of the University of Maryland School of Medicine, said in a journal news release.

"Our study is particularly important for pediatric patients who often require repeated operations for pulmonary valve replacements," he added.

In the study, Simpson's team developed a method to turn skin cells from a biopsy into cells that help create a tissue-engineered pulmonary valve.

The pulmonary valve connects the heart to the pulmonary artery, which carries blood from the heart to the lungs.

"We created a pulmonary valve that is unique to the individual patient and contains living cells from that patient," study senior co-author Dr. Sunjay Kaushal said in the news release. "That valve is less likely to be destroyed by the patient's immune system, thus improving the outcome and hopefully increasing the quality of life for our patient."

Some day, "it may be possible to generate this pulmonary valve by using a blood sample instead of a skin biopsy," Kaushal added.

The next step in this research will be to implant the new valves in patients to assess how well they work and how long they last, the study authors said.

More information

The U.S. National Library of Medicine has more about heart valve problems.

SOURCE: Annals of Thoracic Surgery, news release, Sept. 2, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ‘Prepped’ by tumor cells, lymphatic cells encourage breast cancer cells to spread
2. Circulating tumor cell clusters more likely to cause metastasis than single cells
3. Research shows how premalignant cells can sense oncogenesis and halt growth
4. Sorting cells with sound waves
5. Removing Programming Material After Inducing Stem Cells Could Improve Their Regeneration Ability
6. Conclusive evidence on role of circulating mesenchymal stem cells in organ injury
7. Seniors Sleep Woes May Be Linked to Loss of Brain Cells
8. Natural (born) killer cells battle pediatric leukemia
9. Club cells are bad guys during flu infection
10. Researchers identify a mechanism that stops progression of abnormal cells into cancer
11. How breast cancer usurps the powers of mammary stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Skin Cells Used to Create Heart Valve for Growing Kids
(Date:2/11/2016)... Island, NY (PRWEB) , ... February 11, 2016 ... ... has enhanced and updated its hallmark resource, Infusion Therapy Standards of Practice, to ... leader in vein illumination with an estimated 85% share of the market, facilitates ...
(Date:2/11/2016)... ... February 11, 2016 , ... The annual list showcases the 20 Most Promising ... team dedication and commitment to the SharePoint ecosystem. A panel of experts and ... goal is to recognize and promote technology entrepreneurship. , The survey was made ...
(Date:2/11/2016)... , ... February 11, 2016 , ... ... dynamometers and ergoFET force gauges used in physical therapy, occupational therapy and sports ... sensor for resistance cord exercise and therapy, introduces its new microFET Digital Pinch ...
(Date:2/11/2016)... (PRWEB) , ... February 11, 2016 , ... ... coverage results in significantly higher rates of several common cancer screenings, especially among ... in better outcomes and survival rates. , The study,“What Does Medicaid Expansion ...
(Date:2/10/2016)... ... February 10, 2016 , ... Sherly Sulaiman, certified clinical ... of therapeutic sessions to help Los Angeles-area actors cope with rejection, improve their ... series, known as “Mindfulness for Actors and Artists,” has been featured in ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Fla. , Feb. 11, 2016 PLAD, ... started out 2016 with sales exceeding company targets, are ... have received their trademark from the United States Patent ... Bobby Clark , Chief Executive Officer of PLAD, Inc.  ... of Pennsylvania with two new ...
(Date:2/11/2016)... Feb. 11, 2016  Delcath Systems, Inc. (NASDAQ: ... device company focused on oncology with an emphasis ... cancers, announces the engagement of Lars E. ... Medical Consultant. Dr. Birgerson will provide strategic medical ... operations team to help ensure timely facilitation of ...
(Date:2/11/2016)... ENGLEWOOD, Colo. , Feb. 11, 2016  Aytu ... on developing treatments for urological and related conditions, announced ... for the second fiscal quarter of 2016 on Tuesday, ... will review recent accomplishments and provide an overview of ... financial results for the quarter ended December 31, 2015. ...
Breaking Medicine Technology: