Navigation Links
Skin Cells Used to Create Heart Valve for Growing Kids
Date:9/3/2014

WEDNESDAY, Sept. 3, 2014 (HealthDay News) -- While artificial heart valves have long been available to adults, making permanent valves for children has been challenging because kids' bodies keep growing.

But researchers say they've found a way around that, using a child's skin cells to make a new pulmonary valve for the youngster's heart to replace a faulty one.

Using a child's own skin cells to create the new valve reduces the risk of rejection, the researchers explained, and means the valve can grow with the patient -- reducing the need for future valve replacements.

The findings appear in the September issue of the Annals of Thoracic Surgery.

"Current valve replacements cannot grow with patients as they age, but the use of a patient-specific pulmonary valve would introduce a 'living' valvular construct that should grow with the patient," lead author David Simpson, of the University of Maryland School of Medicine, said in a journal news release.

"Our study is particularly important for pediatric patients who often require repeated operations for pulmonary valve replacements," he added.

In the study, Simpson's team developed a method to turn skin cells from a biopsy into cells that help create a tissue-engineered pulmonary valve.

The pulmonary valve connects the heart to the pulmonary artery, which carries blood from the heart to the lungs.

"We created a pulmonary valve that is unique to the individual patient and contains living cells from that patient," study senior co-author Dr. Sunjay Kaushal said in the news release. "That valve is less likely to be destroyed by the patient's immune system, thus improving the outcome and hopefully increasing the quality of life for our patient."

Some day, "it may be possible to generate this pulmonary valve by using a blood sample instead of a skin biopsy," Kaushal added.

The next step in this research will be to implant the new valves in patients to assess how well they work and how long they last, the study authors said.

More information

The U.S. National Library of Medicine has more about heart valve problems.

SOURCE: Annals of Thoracic Surgery, news release, Sept. 2, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ‘Prepped’ by tumor cells, lymphatic cells encourage breast cancer cells to spread
2. Circulating tumor cell clusters more likely to cause metastasis than single cells
3. Research shows how premalignant cells can sense oncogenesis and halt growth
4. Sorting cells with sound waves
5. Removing Programming Material After Inducing Stem Cells Could Improve Their Regeneration Ability
6. Conclusive evidence on role of circulating mesenchymal stem cells in organ injury
7. Seniors Sleep Woes May Be Linked to Loss of Brain Cells
8. Natural (born) killer cells battle pediatric leukemia
9. Club cells are bad guys during flu infection
10. Researchers identify a mechanism that stops progression of abnormal cells into cancer
11. How breast cancer usurps the powers of mammary stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Skin Cells Used to Create Heart Valve for Growing Kids
(Date:3/24/2017)... ... March 24, 2017 , ... According to a new ... invalid because it does not obey the rules Congress has directed the CBO to ... which the GOP reform would restore. Yet, it estimates a reduction in employer-based coverage ...
(Date:3/24/2017)... Diego, Calif. (PRWEB) , ... March 24, 2017 ... ... has raised over $100,000 for its innovative EcoQube Frame vertical micro-veggies garden on ... the instant demand for the product – with nearly 2,000 consumers (and counting) ...
(Date:3/24/2017)... ... March 24, 2017 , ... Viewers who like to educate ... historical facts, cultural practices, goods, services, and societal issues tend to appreciate and love ... the popular practice of utilizing running events for causes around the world. ...
(Date:3/24/2017)... ... March 24, 2017 , ... “End Time GPS”: a dauntless and ... “End Time GPS” is the creation of published author, Wesley Gerboth, a World ... military munitions and space-vehicle projects. Now, at age ninety-one, he shares the Wisdom God ...
(Date:3/23/2017)... ... 2017 , ... A recent report from the National Council on Teacher Quality ... report suggests, based on a review of GPA and SAT/ACT requirements at 221 institutions ... U.S. It argues that this higher bar should be set by states, by the ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... FinancialBuzz.com News Commentary  ... According to new data ... research, the legal cannabis market is projected to continue to ... signals from the current presidential administration. The report created by ... drivers of growth in this industry are the passage and ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... offering. ... is very strong with a total of 97 drug candidates. Pharma giant ... are involved in the development of the IPF therapeutics. The IPF pipeline ... stage, 15 are in Phase II stage, 12 are in Phase I ...
(Date:3/24/2017)... March 24, 2017 A ReportsnReports.com report says, ... growing rapidly as the global sales of Adcetris and Kadcyla have ... the antibody drug conjugates market is driven by large number of ... wider therapeutic window offered by ADCs. ... Browse 3 Tables and 94 Figures, 10 Major ...
Breaking Medicine Technology: