Navigation Links
Skin Cells Used to Create Heart Valve for Growing Kids
Date:9/3/2014

WEDNESDAY, Sept. 3, 2014 (HealthDay News) -- While artificial heart valves have long been available to adults, making permanent valves for children has been challenging because kids' bodies keep growing.

But researchers say they've found a way around that, using a child's skin cells to make a new pulmonary valve for the youngster's heart to replace a faulty one.

Using a child's own skin cells to create the new valve reduces the risk of rejection, the researchers explained, and means the valve can grow with the patient -- reducing the need for future valve replacements.

The findings appear in the September issue of the Annals of Thoracic Surgery.

"Current valve replacements cannot grow with patients as they age, but the use of a patient-specific pulmonary valve would introduce a 'living' valvular construct that should grow with the patient," lead author David Simpson, of the University of Maryland School of Medicine, said in a journal news release.

"Our study is particularly important for pediatric patients who often require repeated operations for pulmonary valve replacements," he added.

In the study, Simpson's team developed a method to turn skin cells from a biopsy into cells that help create a tissue-engineered pulmonary valve.

The pulmonary valve connects the heart to the pulmonary artery, which carries blood from the heart to the lungs.

"We created a pulmonary valve that is unique to the individual patient and contains living cells from that patient," study senior co-author Dr. Sunjay Kaushal said in the news release. "That valve is less likely to be destroyed by the patient's immune system, thus improving the outcome and hopefully increasing the quality of life for our patient."

Some day, "it may be possible to generate this pulmonary valve by using a blood sample instead of a skin biopsy," Kaushal added.

The next step in this research will be to implant the new valves in patients to assess how well they work and how long they last, the study authors said.

More information

The U.S. National Library of Medicine has more about heart valve problems.

SOURCE: Annals of Thoracic Surgery, news release, Sept. 2, 2014

--


'/>"/>
Copyright©2014 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ‘Prepped’ by tumor cells, lymphatic cells encourage breast cancer cells to spread
2. Circulating tumor cell clusters more likely to cause metastasis than single cells
3. Research shows how premalignant cells can sense oncogenesis and halt growth
4. Sorting cells with sound waves
5. Removing Programming Material After Inducing Stem Cells Could Improve Their Regeneration Ability
6. Conclusive evidence on role of circulating mesenchymal stem cells in organ injury
7. Seniors Sleep Woes May Be Linked to Loss of Brain Cells
8. Natural (born) killer cells battle pediatric leukemia
9. Club cells are bad guys during flu infection
10. Researchers identify a mechanism that stops progression of abnormal cells into cancer
11. How breast cancer usurps the powers of mammary stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Skin Cells Used to Create Heart Valve for Growing Kids
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... San Francisco, CA (PRWEB) , ... October 12, ... ... and Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus ... sleep apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris F. ... AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking place ... the field of medical informatics, this prestigious award is presented to an individual whose ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a ... of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners ... October 11, 2017. , The annual award competition recognizes editorial and design excellence across ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... first interactive health literacy software tool, and the Cancer Patient Education Network (CPEN), ... patient education, today announce a new strategic alliance. , As CPEN’s strategic ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... INDIANAPOLIS , Oct. 2, 2017  Eli Lilly ... its financial results for the third quarter of 2017 ... a conference call on that day with the investment ... performance. The conference call will begin at ... public can access a live webcast of the conference ...
(Date:10/2/2017)... , Oct. 2, 2017 Halo Labs announces the ... analysis system called the HORIZON at MIBio 2017 in ... subvisible and visible particulate matter in biopharmaceutical samples with unprecedented speed ... of the novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
(Date:9/28/2017)... -- Hill-Rom Holdings, Inc. (NYSE: HRC), will host its ... on Friday, November 3, 2017, beginning at 7:00 a.m. ... 8:30 a.m. (CDT) / 9:30 a.m. (EDT). ... and guidance for 2018, Hill-Rom executives will also highlight ... and long-range financial outlook through 2020. ...
Breaking Medicine Technology: