Navigation Links
Single men, smokers at higher risk for oral human papillomavirus infection, Moffitt study shows
Date:7/2/2013

Smokers and single men are more likely to acquire cancer-causing oral human papillomavirus (HPV), according to new results from the HPV Infection in Men (HIM) Study. Researchers from Moffitt Cancer Center, the National Cancer Institute, Mexico and Brazil also report that newly acquired oral HPV infections in healthy men are rare and when present, usually resolve within one year.

The study results appeared in the July issue of The Lancet.

HPV infection is known to cause virtually all cervical cancers, most anal cancers and some genital cancers. It has recently been established as a cause of the majority of oropharyngeal cancers, a malignancy of the tonsils and base of tongue.

HPV-related oropharyngeal cancer is rare, but rates have been increasing rapidly, especially among men. To determine the pattern of HPV acquisition and persistence in the oral region, researchers evaluated the HPV infection status in oral mouthwash samples collected as part of the HIM Study, which was originally designed to evaluate the natural history of genital HPV infections in healthy men.

"Some types of HPV, such as HPV16, are known to cause cancer at multiple places in the body, including the oral cavity," said study lead author Christine M. Pierce Campbell, Ph.D., M.P.H., a postdoctoral fellow in Moffitt's Center for Infection Research in Cancer. "We know that HPV infection is associated with oropharyngeal cancer, but we don't know how the virus progresses from initial infection to cancer in the oral cavity. One aspect of the HIM Study is to gather data to help us understand the natural history of these infections."

During the first 12 months, nearly 4.5 percent of men in the study acquired an oral HPV infection. Less than 1 percent of men in the study had an HPV16 infection, the most commonly acquired type, and less than 2 percent had a cancer-causing type of oral HPV.

Their findings are consistent with previous studies showing a low prevalence of oral HPV cancers. However, this study shows the acquisition of cancer-causing oral HPV appeared greater among smokers and unmarried men.

"Additional HPV natural history studies are needed to better inform the development of infection-related prevention efforts," said Anna R. Giuliano, Ph.D., director of Moffitt's Center for Infection Research in Cancer. "HPV16 is associated with the rapid increase in incidence of oropharyngeal cancer, most noticeably in the United States, Sweden and Australia, where it is responsible for more than 50 percent of cases. Unfortunately, there are no proven methods to prevent or detect these cancers at an early stage."

The researchers note that persistent oral HPV16 infection may be a precursor to oropharyngeal cancer, similar to how persistent cervical HPV infection leads to cervical pre-cancer.


'/>"/>

Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Related medicine news :

1. Platinum Artist Gregory Abbott Introduces New Website and Singles
2. Try STD Dating at PositiveSingles.com-Your Online Home for Dating with Herpes, Dating with HIV & Dating with HPV
3. Imprivata Tops Single Sign-On Category in KLAS 2013 Mid-Term Performance Review
4. Upstart Bachelorista Inc. Releases Tell-All Playbook For Single Women
5. Johns Hopkins surgeons among the first in the country to perform a robotic single-site hysterectomy
6. Imprivata is the Most Widely Selected Single Sign-On Solution by U.S. MEDITECH Customers According to HIMSS Analytics
7. Talk Therapy Can Ease Depression, But No Single Type Deemed Best
8. MEDIA ALERT: Imprivata and Dell Wyse to Discuss Benefits of Desktop Virtualization and Single Sign-On in Healthcare at Citrix Synergy
9. LAPD Singles Out Narconon Drug Prevention and Education for Special Commendation
10. Northern Westchester Hospital Surgeon Reaches New Single-Incision Robot-Assisted Gallbladder Removal Surgery Milestone
11. Unique group for single fathers due to cancer offers support
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2016)... ... 2016 , ... Bluvault ( Bluvault Inc. ) today announced ... clients of Coupa ( Coupa Software ) and other Cloud software, powered by ... component in the suite of innovative implementation services offered by Bluvault. , "Our ...
(Date:5/6/2016)... ... May 06, 2016 , ... Online HR/benefits platforms offer a range of benefits ... traditional brokers and health plans. “ The Rapid Emergence of Online Benefits Firms: Strategies ... Services, Inc. (AIS), will offer an accurate picture of online benefits today, and the ...
(Date:5/6/2016)... ... May 06, 2016 , ... The International Yoga Teacher Training schoo ... the island close to the town famous for its sunsets, Oia. This all inclusive ... continue to have an amazing experience in Greece, we just can’t stay away” says ...
(Date:5/6/2016)... ... May 06, 2016 , ... Few events in healthcare ... mostly for its cost despite its potential to wipe out a silent killer, ... of a class called direct-acting antivirals (DAAs)—have created fallout in the courts and ...
(Date:5/6/2016)... (PRWEB) , ... May 06, 2016 , ... “ Crossing ... Press) shares accounts of dying patients who have allowed those holding vigil to glimpse ... Kuykendall, RN, BSN, CHPN, hopes to help readers spiritually and practically gain insight into ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... May 5, 2016 , First quarter ... revenues of $964 million , First quarter ... $0.40 , Company revises 2016 financial guidance; ... $4.03 billion and 2016 adjusted diluted non-GAAP earnings per share ... Company provides updates regarding Generics business and manufacturing facility restructuring ...
(Date:5/5/2016)... May 5, 2016  Diagnostic imaging has been ... to concerns that these tests cause health care costs to ... imaging, as well as the adoption of new ... medical peripherals that help health care providers cut costs, while ... medical imaging is a renowned authorized reseller of the ...
(Date:5/5/2016)... 2016 Research and Markets has announced the ... 5 EU Markets"  report to their offering.  ,     (Logo: ... on the current Positron Emission Tomography (PET) scanner and cyclotron ... which includes France , Germany ... and the United Kingdom . ...
Breaking Medicine Technology: