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Single-Pill Combinations Diovan HCT and Exforge Approved in US as First-Line Treatments for High Blood Pressure
Date:8/3/2008

present when Tekturna is used in combination with ACE inhibitors or beta blockers. Exforge and Diovan HCT may be used as the first medicine if your doctor decides you are likely to need more than one medicine to lower your high blood pressure.

Important Considerations:

What is the most important information I should know about Diovan, Diovan HCT, Tekturna, or Exforge?

If you become pregnant, stop taking Diovan, Diovan HCT, Tekturna, or Exforge and call your doctor right away. Diovan, Diovan HCT, Tekturna, or Exforge can harm an unborn baby causing injury and even death. If you plan to become pregnant, talk to your doctor about other treatment options to lower your blood pressure before taking Diovan, Diovan HCT, Tekturna, or Exforge.

Do not take Diovan HCT if you have a history of reduced urine output, or have allergic reactions to certain drugs known as sulfonamides. Tell your doctor about all your medical conditions and medicines you take, including liver or kidney problems, lupus or if you take lithium. Additionally, do not take Tekturna if you take cyclosporine.
Serious side effects could occur such as:

-- low blood pressure

-- kidney problems

-- if you take Tekturna and develop an allergic reaction involving

swelling of the face, lips, throat, and/or tongue, which may cause

difficulty in breathing and swallowing stop taking the drug and contact

your doctor immediately.

-- if you take Diovan HCT, a skin rash

-- worsening chest pain with Exforge, especially in patients who already

have severe heart disease.

If you take Diovan HCT and have liver problems or lupus, these conditions may get worse.

If you take Diovan HCT tell your doctor if you develop any of the following signs of fluid and electrolyte problems: dry mouth, thirst, lack of energy, weakness, drowsiness, restlessness, confusion, seizures, muscle pain or cramps, muscle fatigue, very lo
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SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

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