Navigation Links
Simvastatin Leads Pfizer's Lipitor in Second-Line Patient Share for the Treatment of Dyslipidemia
Date:5/13/2008

Results from the ENHANCE Trial Impacting Physician Prescribing Patterns,

According to a New Report from Decision Resources

WALTHAM, Mass., May 13 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that simvastatin (Merck's Zocor, generics) leads Pfizer's Lipitor in second-line patient share -- 22.9 percent versus 14.7 percent. Most patients progressing to simvastatin do so after switching from Lipitor. Surveyed primary care physicians and cardiologists cite simvastatin's better reimbursement and formulary status as the primary reason to prescribe simvastatin instead of Lipitor. Nevertheless, despite the availability of generic statins, more than 75 percent of Lipitor's prescriptions stem from first-line therapy.

The report entitled Treatment Algorithms in Dyslipidemia also finds that, prior to the release of the ENHANCE trial results, Merck/Schering-Plough's Vytorin and AstraZeneca's Crestor also gained significant second-line patient shares-13.1 percent and 10.9 percent, respectively. These gains reflect physicians' efforts to boost efficacy in patients whose initial low-density lipoprotein (LDL) lowering treatment had been less than optimal; surveyed physicians perceive these agents to offer the best LDL-reducing ability. However, 47 percent of surveyed primary care physicians and 49 percent of surveyed cardiologists have changed their prescribing of Merck/Schering- Plough's Zetia and Vytorin because of data from the ENHANCE trial, which showed that the addition of Zetia to simvastatin treatment did not significantly change carotid artery thickness. The majority of surveyed physicians now prescribe Vytorin and Zetia in fewer new patients, with a smaller percentage of physicians switching patients off of these drugs.

"Cardiologists we surveyed expect to decrease their first- and second-line prescriptions for Vytorin between 2008 and 2010,
'/>"/>

SOURCE Decision Resources
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
2. Nursing professor leads the way for telepsychiatry by nurses to treat postpartum depression
3. Prisoner HIV program leads to continuum of medical care after release
4. Osteotech Announces the Unexpected Passing of Audit Committee Member Leads to Receipt of Nasdaq Deficiency Letter
5. Minimally invasive pancreas surgery leads to fewer complications, study finds
6. UQ leads the way on complementary medicine research
7. Prostate cancer screening program leads to bigger fall in death rates than surrounding areas
8. When positive thinking leads to financial irresponsibility like compulsive gambling
9. Drug compound leads to death of ovarian cancer cells resistant to chemotherapy
10. Eli Manning Leads March for Babies in Manhattan
11. MRI before surgery leads to better-adapted treatment for breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 ... are only about half as likely as white women to ... indicates, and the racial disparity persists even when donor eggs ... white patients became pregnant after IVF, compared to about 17 ... cycles over two years to tease out the impact of ...
(Date:10/22/2014)... Salamon HealthDay Reporter TUESDAY, ... conventional in vitro fertilization (IVF) -- the incubation of embryos ... a device inside the vagina, new research suggests. Scientists ... called an INVOcell, might sharply cut costs for pricey IVF ... more accessible to those who don,t live near big-city assisted ...
(Date:10/22/2014)... HealthDay Reporter TUESDAY, Oct. 21, ... Ebola while working for NBC News in Liberia has ... isolation unit at Nebraska Medical Center in Omaha, where he had ... A blood test confirmed by the U.S. Centers for Disease ... to Providence, R.I., NBC News reported Tuesday night. ...
(Date:10/20/2014)... PA (PRWEB) October 20, 2014 Allegheny ... minimally-invasive procedure that enables physicians to repair a damaged ... The MitraClip system, developed by Abbott ... (MR), a progressive and life-threatening condition in which the ... blood to flow backward from the heart’s left ventricle ...
(Date:10/20/2014)... 20, 2014 Women’s health specialist, Dr. ... & Gynecology of Columbus, Inc., A Division of MaternOhio ... to more than 100,000 patients annually. Dr. Murphy will ... and stages of a women’s life. She is accepting ... in Westerville and Dublin. , Dr. Murphy offers a ...
Breaking Medicine News(10 mins):Health News:Black Women Fare Worse With Fertility Treatments, Study Says 2Health News:Black Women Fare Worse With Fertility Treatments, Study Says 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3
... epic, a prince donates his youth to his father so that ... kind of help is at hand now. For scientists say they ... ageing process. And by manipulating that gene perhaps one could live ... in extending the lifespan of animals that are subjected to a ...
... According to the latest on breast-feeding, there is no hard and ... Most young mothers would be more than glad to ... feeding, can prove too painful for motherly feelings to override. ... a horrendous time trying to breastfeed when her daughter Deborah was ...
... nurse to avoid common errors which effect 1in 10 patients. ... workers help spread disease to unexpected quarters. ,The ... the world and lessen the number of health care related ... in both developed and developing countries. ,The nine ...
... higher levels of calcium and vitamin D are significantly more ... damage that can increase risk of cognitive impairment, dementia, ... co-investigators from Duke and the University of North Carolina examined ... (79 men, 153 women) between the ages of 60 and ...
... epidemic diseases has entered the phase of clinical experiments, claimed ... that rely on antigen or antibody test, the new technology ... or RNA, to confirm epidemic diseases such as hepatitis or ... of US National Institutes of Health (NIH). ,Xiang ...
... that can enable the blind to hear what they cannot see ... reads texts through an embedded system and converts them into voice ... it can only read text, but later it is likely to ... team that took six months to develop the device and the ...
Cached Medicine News:Health News:Gene Responsible for Ageing Process Discovered and Calorie Restriction Could Help 2Health News:New Research Promises To Take The Pain Off Breast Feeding 2Health News:New Research Promises To Take The Pain Off Breast Feeding 3Health News:UN Agencys Checklist on Health Care Error 2Health News:Higher Intake of Calcium and Vitamin D Linked With Brain Lesions in Older People 2
(Date:10/22/2014)... ATLANTA , Oct. 22, 2014  CryoLife, Inc. ... and tissue processing company focused on cardiac and vascular ... , President and Chief Executive Officer, has been elected ... 2014. Steven G. Anderson , Executive ... Pat has proven to be an excellent leader who ...
(Date:10/22/2014)... Oct. 21, 2014  Early symptoms of diabetic ... unnoticed, but new technology, coupled with yearly, comprehensive ... to earlier detection of eye diseases, including those ... Americans. If left untreated, these diseases can potentially ... Recently, optometric researchers have deployed a ...
(Date:10/22/2014)... , Oct. 22, 2014 InVivo Therapeutics Holdings ... is revolutionizing spinal cord injury (SCI) treatment ... shown to outperform in tissue regrowth in the spinal ... Made from an FDA approved polymer, the scaffold ultimately ... harmless to the human body. NVIV has recently attracted ...
Breaking Medicine Technology:Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3
... Lupus,Research (ALR) commends the Senate on its passage of ... Health Week that begins,annually on Mother,s Day. The resolution, ... calls on all Americans to take the,week of May ... themselves on,women,s health issues, and recognizes the importance of ...
... dial, not an on/off,light switch; a discovery that hints ... MEMPHIS, Tenn., May 12 A St. Jude Children,s,Research ... immune,regulators, do not use simple on/off switches to govern ... they,possess sophisticated molecular controls that enable them to adjust ...
Cached Medicine Technology:Lupus Under the Spotlight: U.S. Congress Shows Support for Women's Health Issues 2St. Jude Study Shows How T Cell's Machinery Dials Down Autoimmunity 2St. Jude Study Shows How T Cell's Machinery Dials Down Autoimmunity 3St. Jude Study Shows How T Cell's Machinery Dials Down Autoimmunity 4
... High Throughput Sorter RSD ProVolume ... laboratories in the field of pre-sorting ... only of considerable speed but is ... Module can be integrated. Secure and ...
... Sorting System RS 800 can sort different ... manual sorting are not necessary anymore and ... in a very timesaving and economical way ... Optionally a Tube Type Identification via Cap ...
... Nanogen offers reagents to detect sequences ... parainfluenza virus 1, 2 and 3; ... respiratory syncytial virus A and B. ... to create homebrew tests., ...
... Reagents provide molecular labs a more advanced ... using our MGB technology, combined with post-PCR ... able to provide molecular labs more powerful ... specific organisms or genetic mutations associated with ...
Medicine Products: