Navigation Links
Simplified heart-risk guideline may miscalculate risk for millions
Date:9/9/2010

A method that is widely used to predict the risk of a major coronary event may over- or underestimate risk for millions of Americans, according to a study directed by a researcher at the San Francisco VA Medical Center and the University of California, San Francisco.

The method in question is the simplified version of the so-called Framingham model, which is used to estimate a patient's 10-year risk of a heart attack, stroke, or other coronary event based on risk factors such as age, cholesterol levels, blood pressure, and smoking. National guidelines recommend using the risk estimates generated by the Framingham model to classify patients as among one of three risk groups. Guidelines recommend more aggressive strategies to treat cholesterol in patients classified into higher-risk groups.

The original Framingham model uses a complicated mathematical equation to calculate risk, while the simplified version is based on a point system, with a certain number of points for each risk factor.

"We thought there might be significant differences between the two methods, which would have significant impacts on how people are treated for cholesterol," says principal investigator Michael Steinman, MD, a physician at SFVAMC and an assistant professor of medicine at UCSF. "And in fact, that turned out to be the case."

For the study, which appears in the Online First section of the "Journal of General Internal Medicine," the researchers assessed data from 2,543 subjects who participated from 2001 to 2006 in National Health and Nutrition Examination Surveys sponsored by the Centers for Disease Control and Prevention. The subjects were chosen to be representative of 39 million adults in the United States for whom guidelines recommend using the Framingham method to predict future cardiovascular risk.

For each subject, the researchers calculated risk based on the original Framingham model and on the simplified model, and comp
'/>"/>

Contact: Kristen Bole
kristen.bole@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Clinical trials: Comprehension unaffected by simplified consent forms or payment
2. Study Results Validate Shape-HF as Simplified, Portable Cardiopulmonary Exercise Testing System
3. New guidelines to ease sleepless nights
4. Adherence to practice guidelines may reduce bleeding in cirrhosis patients
5. ASTRO publishes whole breast irradiation guidelines
6. New vitamin D guidelines
7. Experts Issue New Guidelines on Breast Cancer Drugs
8. Screening Guidelines Miss Many Kids With High Cholesterol
9. ESMO publishes updated guidelines on cancer care
10. Updated HIV therapy guidelines would reduce risk of transmission, save lives, billions in costs
11. New cancer guidelines: Exercise during and after treatment is now encouraged
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... (PRWEB) July 25, 2014 Drexel University ... D. Weber, MD, MS, FACP, has been appointed vice dean ... will join Drexel from The Commonwealth Medical College, where she ... dean for clinical affairs, and professor of medicine. , ... Commonwealth Medical College, Weber had a major role in many ...
(Date:7/25/2014)... News) -- Babies seem to learn even before they,re ... women are 34 weeks pregnant, their unborn babies can ... a familiar nursery rhyme, the researchers report. "The ... in the developing fetus," Charlene Krueger, nursing researcher and ... Nursing, said in a university news release. "This research ...
(Date:7/25/2014)... sent patients to designated cardiac receiving centers dramatically increased ... in Arizona, according to a study published online yesterday ... , "We knew lives would be saved if the ... arrest care and we were able to get cardiac ... done for Level 1 trauma patients," said lead study ...
(Date:7/25/2014)... Parkulture is proud to ... parkour instructor, Jared “JJ” Woods, will be competing on ... Ninja Warrior. The show will premiere on local affiliates ... rerun on the new Esquire Network on Tuesday, July ... has been balancing careers as a professional stuntman for ...
(Date:7/25/2014)... 2014 In today’s technological era, every ... supporting devices. This benefits the organization in various ways. ... attacks which can destroy the confidential information and processes ... and Compliance (EGRC) manage and protect the enterprise from ... cause loss in dollars to the comp may. The ...
Breaking Medicine News(10 mins):Health News:Valerie D. Weber, MD, Appointed Vice Dean for Education at Drexel University College of Medicine 2Health News:Valerie D. Weber, MD, Appointed Vice Dean for Education at Drexel University College of Medicine 3Health News:Rhymes Reveal Evidence of Learning in the Womb 2Health News:New EMS system in Arizona dramatically improves survival from cardiac arrest 2Health News:New EMS system in Arizona dramatically improves survival from cardiac arrest 3Health News:Jared “JJ” Woods Prepares for American Ninja Warrior City Finals 2Health News:Jared “JJ” Woods Prepares for American Ninja Warrior City Finals 3Health News:North America Enterprise Governance, Risk, and Compliance Market is Expected to Reach $3,972.6 Million in 2018 - New Report by MicroMarket Monitor 2Health News:North America Enterprise Governance, Risk, and Compliance Market is Expected to Reach $3,972.6 Million in 2018 - New Report by MicroMarket Monitor 3Health News:North America Enterprise Governance, Risk, and Compliance Market is Expected to Reach $3,972.6 Million in 2018 - New Report by MicroMarket Monitor 4Health News:North America Enterprise Governance, Risk, and Compliance Market is Expected to Reach $3,972.6 Million in 2018 - New Report by MicroMarket Monitor 5Health News:North America Enterprise Governance, Risk, and Compliance Market is Expected to Reach $3,972.6 Million in 2018 - New Report by MicroMarket Monitor 6
... may be the way to make a living, but it ... new study from the Universit de Montral, office-workers have become ... activity may partly explain the rise in obesity. Their findings, ... , may have health implications for the millions of people ...
... , MONDAY, Oct. 4 (HealthDay News) -- Children whose ... brain chemical serotonin because of gene mutations may be ... later in life, Norwegian researchers report. Serotonin ... important role during development, especially in the development of ...
... of chronic diseases to the top of the EU ... Kidney Health , the EU Diabetes Working Group and ... the European Parliament, together with representatives of health professionals and ... these chronic diseases urgently, they threaten the "Europe 2020 strategy", ...
... CHANGES , The use of a nasal continuous positive ... may cause craniofacial changes in adults with obstructive sleep ... Vancouver, BC, Canada, analyzed baseline and follow-up radiographs from ... for a minimum of 2 years. Changes in craniofacial ...
... SAN FRANCISCO Implementing a Medical Home practice model ... provide comprehensive care to more patients, and to offer ... with their doctors, recommendations and reduce emergency room visits ... 4, 2010, at the American Academy of Pediatrics (AAP) ...
... -- A new vaccine added to standard therapy appears to ... the most deadly form of brain cancer, according to a ... University of Texas MD Anderson Cancer Center. The vaccine ... most aggressive form of the disease. "About a third ...
Cached Medicine News:Health News:Is your job making you fat? 2Health News:New Clues to Possible Genetic Basis for ADHD 2Health News:New Clues to Possible Genetic Basis for ADHD 3Health News:Heart, kidney, diabetes and cancer MEP groups league against chronic disease to seek European commitment 2Health News:Heart, kidney, diabetes and cancer MEP groups league against chronic disease to seek European commitment 3Health News:Chest news briefs: CPAP may cause facial changes 2Health News:Medical home care approach improves efficiency and care at clinic for low-income families 2Health News:Duke vaccine extends survival for patients with deadly brain cancers 2Health News:Duke vaccine extends survival for patients with deadly brain cancers 3
(Date:7/24/2014)... MARSEILLE , Frankreich, July 24, ... , Weltweite Exklusivlizenz der Universität ... von Tests auf SF3B1-Mutationen, einschließlich von Next-Generation-Sequencing ... Test weist Mutationen des SF3B1-Gens nach, die ... günstigen Krankheitsverlauf vermuten lassen  QIAGEN ...
(Date:7/24/2014)... 24, 2014  Abaxis, Inc. (NasdaqGS: ABAX ... systems, today reported financial results for the first fiscal ... overview: , Revenues of $47.5 million, up 10% ... of $0.21, up 50% over last year,s comparable quarter. ... of $7.2 million, up 20% over last year,s comparable ...
(Date:7/24/2014)... -- Amgen (NASDAQ: AMGN ) today announced that ... July 29, 2014, after the close of the U.S. financial ... with the investment community at 2 p.m. PT. Participating in ... , chairman and chief executive officer, and other members of ... conference call will be simultaneously broadcast over the Internet and ...
Breaking Medicine Technology:QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 3QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 2Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 3Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 4Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 6Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 7Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 8Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 9Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 10Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 11Amgen Announces Webcast of 2014 Second Quarter Financial Results 2
... Goldmann standard automatic or manual ... with white/white, blue/yellow or red/white stimuli/background ... or classic 4-2 threshold strategy. Examination ... grids (including 30-2, 24-2, and 10-2). ...
The Oculus easyfield is an exciting new compact perimeter to do automatic static perimetry up to 30 degrees eccentricity. It has been designed for the combined use as a visual field screener and peri...
... Designed around the patented Interzeag ... 301 sets the trend in ... Ideal for routine screening and ... performance, accuracy and quality of ...
Focus Toric Monthly lenses. All the advantages of Focus Monthly lenses, now available for patients with astigmatism. Recommended for daily wear. Also approved for extended wear (1-7 days)....
Medicine Products: