Navigation Links
Simpler and cheaper antibiotic prophylaxis with insertion of nutrition catheter in the stomach

Researchers at Karolinska Institutet recommends a new routine for protection against infection when percutaneous endoscopic gastrostomy (PEG), a tube for feeding directly through the abdominal wall, is surgically inserted in the stomach. The new routine is both simpler and cheaper than the one used today. The method, presented in the British Medical Journal, has been clinically tested on over 200 patients at the Karolinska University Hospital in Solna, Stockholm County, Sweden.

PEG is typically used for patients unable to swallow and eat in the usual way, and used when improvement in the short term is not expected, for example, in case the patient has throat cancer, esophagus cancer or got a stroke. In Sweden there are several thousand PEG operations per year, and surgery is increasing. One problem with surgery is that the risk of infection is high, which at worst can lead to death. To reduce the risk of infection, cefuroxime, a type of liquid antibiotics for use directly in the blood stream is given today, one hour before surgery.

"It is always difficult for the operating doctor to know whether the infection preventive treatment has been given on time, which could stop the whole operation process", says Dr John Blomberg, PhD Student at Karolinska Institutet and Senior Physician at Karolinska University Hospital.

"In some cases, it is impossible to insert a PEG and then the antibiotics have been given unnecessarily. When a PEG operation fails, which occurs in every ten cases, it usually depends on how the internal organs are located in relation to the abdominal wall and stomach", Dr Blomberg continues.

With the new method for protection against infection, which he and his colleagues present in the scientific journal BMJ, the patient is instead given different antibiotic drugs, a combination of sulfamethoxazole and trimethoprim, as a direct solution in PEG-catheter after surgery is completed. This routine in combination with a lighter workload and a smaller drug cost for hospitals makes this new procedure reduce the cost for PEG operations considerably.

The present study has been done on 234 patients between 2005 and 2009, half of whom were treated with cefuroxime and the other half treated with the mixture of sulfamethoxazole and trimethoprim. Of these 14 patients treated with cefuroxime and 10 patients treated with the mixture of sulfamethoxazole and trimethoprim got an infection. Therefore there are several reasons to recommend this new way of giving antibiotics at PEG operations.

"Both methods give equivalent results in terms of reduced risk of infection for the patient. But the new method is much simpler, and at least ten times cheaper", says Dr Blomberg.


Contact: Press Office
Karolinska Institutet

Related medicine news :

1. New Implanted Defibrillator May Be Simpler, Safer
2. Launching New Cloud Server Technologies on Website Hosting and Much Cheaper Web Hosting
3. FDA Urges Limiting Antibiotics in Meat
4. Quick Use of Antibiotics Best for COPD Flare-Ups
5. Antibiotic Resistance Can Last a Year, Review Finds
6. Minilab can quickly identify antibiotic residues in milk, before it leaves the barn
7. Combination antibiotics effective against chlamydia-induced arthritis
8. Antibiotic regimen effective for reactive arthritis
9. Researchers find compound effective in destroying antibiotic-resistant biofilms
10. Misinformation about antibiotics can travel to large audience via Twitter: study
11. Misinformation About Antibiotics Can Travel to Large Audience Via Twitter: Study
Post Your Comments:
(Date:11/27/2015)... ... 2015 , ... There is only one major question facing all law firms ... This question has not been an easy question to answer. Especially when the senior ... younger workforce don’t share the same discipline around working long hours. , In ...
(Date:11/27/2015)... ... , ... A team of Swiss doctors has released a report on mesothelioma ... posted the findings on the website. Click here to read the details now. ... patients who were treated with chemotherapy followed by EPP surgery. Among the 106 patients ...
(Date:11/27/2015)... ... November 27, 2015 , ... ProSidebar: Fashion is ... Pro X. With ProSidebar: Fasion, video editors can easily add an informative sidebar ... minimalist title opener. Utilize presets featuring self-animating drop zones, lines, bars, and text ...
(Date:11/27/2015)... ... 27, 2015 , ... The moment you stop improving is ... fulfilling the needs of advisers and clients but going above and beyond to ... customer service. However, there's always room for improvement, which is why the entire ...
(Date:11/27/2015)... ... 2015 , ... Avid collector, Andrew Hawley from Vintage Rock Posters, announces his ... is one of Joplin's most famous and beautiful concert posters. The concert was held ... Ann Arbor. The According to Hawley, "It is hard to believe that Joplin's stardom ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Marker Testing Market: Supplier Shares, ... their offering.  --> ... the  "2016 Future Horizons and Growth ...
(Date:11/25/2015)... 25, 2015  The American Academy of Pediatrics ... and the March of Dimes cheered today,s signature ... Infants Act of 2015 (S.799), which takes ... born exposed to drugs, such as opioids, and ... all three organizations have worked together leading advocacy ...
(Date:11/25/2015)...  ARKRAY USA , Inc., a ... demonstrating the accuracy of its blood glucose meter systems. ... Diabetes and Cardiovascular Disease in Los Angeles ... ® 01 meter and the Assure ® ... to accurately measure glucose levels in blood is essential ...
Breaking Medicine Technology: