Navigation Links
Simple new bedside screening effectively identifies patients with acute aortic dissection
Date:5/15/2011

ANN ARBOR, Mich. The most lethal and sudden cardiovascular event can be the toughest for doctors to diagnose.

But a study by the University of Michigan Cardiovascular Center shows new guidelines are effective for determining who's most likely suffering from an aortic dissection, which is tearing in the lining of the body's largest blood vessel.

Aortic dissection lead to the sudden death of award-winning TV actor John Ritter in 2003, and brought the world's attention to a heart condition that few survive.

The U-M study shows that with the help of an aortic dissection detection risk score, generated by a simple, bedside screening tool, doctors can usually identify signs or symptoms of acute aortic dissection, which include abrupt, intense pain.

The study was published online ahead of print May 24 in the American Heart Association's journal Circulation.

"The results from this study suggest that the risk score, with the use of only information that is available at the bedside, can identify the vast majority of patients presenting with acute aortic dissection," says study senior author and cardiologist Kim A. Eagle, M.D., a director of the U-M Cardiovascular Center.

Nearly 10,000 Americans suffer aortic dissections each year, and nearly one in three dies before leaving the hospital despite recent advances in diagnostic tools and surgical treatment.

The U-M is the coordinating center for the largest-ever study of aortic dissection patients and the study results were compiled from the International Registry of Acute Aortic Dissection.

Of the 2,538 IRAD patients examined, 95 percent had one or more of the 12 proposed clinical risk markers and 86 percent had at least two of the risk markers.

Patients with acute aortic dissection frequently had an abrupt onset of pain, severe intensity of pain and pain described as ripping or tearing, according to the study.

U-M radiology and cardiology experts helped the American Heart Association, American College of Cardiology and other professional societies create the 2010 thoracic aortic disease guidelines.

The ADD risk score was created from these guidelines to provide doctors with a fast, simple and systematic method for screening large volumes of patients at the bedside.

"Because of its symptoms, aortic dissection is often mistaken for other cardiovascular conditions," says study co-author Adam M. Rogers, M.D., also of U-M.

Those who have lived through aortic dissection describe it as the most painful thing that ever happened to them. Blood, surging from the heart into the main artery, forces open a tiny rip in the aorta's lining that grows and threatens to burst like a dam in a flood.

While tears in the lining of the body's largest blood vessel are rare, occurring in 5,000 to 10,000 patients a year, they have long been known to be deadly. Without emergency attention and treatment and even, often with it the torn lining can continue to rip, block blood flow to key arteries in the body, cause the heart to fail, or make the aorta swell into an aneurysm or rupture entirely.

Aortic dissections are the leading cause of death among people with Marfan syndrome, a genetic disorder that weakens the aorta.

Also at risk are people with other heart valve and aorta problems, high blood pressure, or a family history of aortic dissections. Some people with aortic dissection can achieve a stable state with their condition, at least for a while, but most cases are acute and must be treated quickly.

Aortic dissection's symptoms often mimic those of other cardiovascular conditions resulting in delayed diagnosis. Symptoms include instantaneous onset of severe chest or back pain, sharp drops in blood pressure, altered consciousness, and even limb paralysis.

Only when patients reach an emergency room and undergo tests and scans can the cause be spotted. The two best imaging techniques for finding a dissection are computed tomography, or CT, or trans-esophageal echocardiography.

After diagnosis, ER staff may decide to send the patient to an aortic center that has specialized staff and equipment to handle the condition - such as U-M and the other IRAD participating hospitals.


'/>"/>

Contact: Shantell M. Kirkendoll
smkirk@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related medicine news :

1. Simple Question Sheds Light on Teens Hopes, Dreams
2. Simple chemical cocktail shows first promise for limb re-growth in mammals
3. Simple blood test detects early emphysema in smokers before symptoms appear
4. Simple blood test at discharge could help reduce hospital readmissions for heart failure patients
5. Radio-guided surgery a safe and simple way to remove potentially cancerous nodules in the lung
6. Simple spit and blood tests might detect burnout before it happens
7. Quick, Simple Test Can Detect Concussion in Athletes
8. Toward a fast, simple test for detecting cholera rampaging in 40 countries
9. Simple feedback could be effective therapy for addictive behaviors
10. Simple Screen May Help Spot Depression in College Students
11. Wounded Congresswoman Responds to Simple Commands
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... 20, 2017 , ... Researchers at the University of Pittsburgh School of Medicine ... that may predict response to a particular class of drugs, not just in patients ... The new findings were published in Proceedings of the National Academy of Science. , ...
(Date:2/20/2017)... ... 2017 , ... The StayWell Company and VUCA Health ... health risks, foster behavior change and improve health literacy among patients. VUCA Health, which ... demonstration of its video capability at StayWell booth 3443 during HiMSS. , The ...
(Date:2/20/2017)... ... February 20, 2017 , ... Sensogram Technologies Inc., the world ... visit this week at HIMSS 2017 Conference & Exhibition. The event brings more ... will be featured in the conference’s Connected Health Experience section, an area specifically ...
(Date:2/20/2017)... ... ... a Population Health Software Company, is pleased to announce a move to a larger office ... the size of the previous location while bringing life back to a medical practice building ... are excited to expand our footprint to better serve our growing client base. We ...
(Date:2/20/2017)... ... February 20, 2017 , ... Johns Hopkins All Children's Hospital ... A topping out ceremony on Friday marked the halfway point of construction and lifting ... in Fall 2018, will serve as a center for innovation aimed at finding new ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... Feb. 20, 2017  This report analyzes the worldwide markets ... Million. The report provides separate comprehensive analytics for the ... , Europe , ... and Rest of World. Read the ... and forecasts are provided for the period 2015 through ...
(Date:2/20/2017)... Feb. 20, 2017 Research and Markets has ... Insights, Opportunity, Analysis, Market Shares & Forecast 2017 - 2022" ... ... nearly USD 2 Billion by the year end of 2022 growing ... Market growth can be attributed to factors such as ...
(Date:2/20/2017)... -- Seal Shield LLC ( Jacksonville, FL ... management and disinfection, the ElectroClave™, to the exhibit floor ... Orlando, Fla. from February 20-23, 2017 ... commonplace in today,s healthcare landscape, but with this progression ... the disinfection and tracking of these devices.  The ElectroClave™ ...
Breaking Medicine Technology: