Navigation Links
Simple lab-based change may help reduce unnecessary antibiotic therapy, improve care
Date:2/26/2014

[EMBARGOED UNTIL THURSDAY, FEB. 27] A simple change in how the hospital laboratory reports test results may help improve antibiotic prescribing practices and patient safety, according to a pilot, proof-of-concept study published in Clinical Infectious Diseases and now available online. No longer routinely reporting positive urine culture results for inpatients at low risk for urinary tract infections (UTIs) greatly reduced unnecessary antibiotic prescriptions and did not affect the treatment of patients who did need antibiotics, the study authors found.

Urine cultures for hospitalized patients are often ordered unnecessarily. Positive culture results from patients without any UTI symptoms can lead to antibiotic prescriptions that are of no benefit and may cause harm to patients, including C. difficile infection and subsequent infection with more antibiotic-resistant bacteria.

In the study, conducted in 2013 at Mount Sinai Hospital in Toronto, urine culture results from non-catheterized inpatientsthose at lower risk for developing a UTIwere no longer reported automatically to the ordering physician. Instead, a message was posted to the patient's electronic medical record asking caregivers to call the lab for the results only if a UTI was strongly suspected.

The message reminded providers that "the majority of positive urine cultures from inpatients without an indwelling urinary catheter represent asymptomatic bacteriuria," a condition for which current practice guidelines do not usually recommend antibiotics, unless the patient is pregnant or will be undergoing certain urological procedures.

After the change in how the culture results were reported, the rate of antibiotic treatment for asymptomatic bacteriuria among non-catheterized patients decreased from 48 percent to 12 percent. Treatment rates among patients in the catheterized control groupwhose culture results were routinely reported as beforeremained steady, at 41 percent. Patients with positive culture results were assessed by a study investigator for UTI symptoms within 24 hours. Four UTIs developed among the non-catheterized patients; in all of these cases, clinicians had already started appropriate antibiotic treatment when the urine cultures were ordered, based on the patients' symptoms.

"In clinical medicine, there are many examples of tests that are not routinely processed or reported when they have been shown to be of very low yield or associated with potential harms, and special requests are required in these cases," said lead study author Jerome A. Leis, MD, MSc, of Sunnybrook Health Sciences Centre in Toronto. "We believe this to be true of some urine cultures from medical and surgical floors where we know that the majority of positive results occur in patients without symptoms of urinary tract infection and lead to unnecessary and potentially harmful therapy with antibiotics."

The study authors stressed the need for larger studies to confirm the overall generalizability, safety, and sustainability of such a change in urine culture reporting before it is implemented more broadly and in other practice settings.


'/>"/>
Contact: Jerica Pitts
jpitts@pcipr.com
312-558-1770
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Helping Kids Make Healthy Choices Every Day with the Brilliantly Simple 5-4-3-2-1+10® Program
2. Fast Hidradenitis Suppurativa Cure Review Exposes the Simplest Way to Cure HS Permanently
3. Get Your Practice To A Flying Start In 2014 With These Simple Marketing Tips
4. Pediatrician Offers a Simple Way to Keep New Year's Resolutions and Create Healthy Habits One Month at a Time
5. A New “Ways To Prevent Dementia” Article Introduces to People Simple Tips to Prevent Alzheimer’s and Dementia Disease – Healthreviewcenter
6. Simple Steps to Reduce Risk of Dementia Revealed by 35-Year Study
7. Discover 20 Simple Tips on How to Get Soft Lips - V-kool
8. The Venus Factor Review Exposes the Simplest Method for Body Transformation
9. Discover 17 Simple Tips on How to Reduce Eye Puffiness – V-Kool
10. Discover 16 Simple Tips On How To Improve Posture – V-kool
11. No Medical Exam Life Insurance Is A Simple Method Of Getting Coverage For People Who Have A Pre-Existing Medical Condition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... May 27, 2016 , ... With ... pharmaceutical, medical and food industries. Aside from its GMP accreditation, Validation Center is ... of successfully certified products, services and staff. , Validation Center is ISO17025 accredited ...
(Date:5/26/2016)... DC (PRWEB) , ... May 26, 2016 , ... There ... National Hot Dog and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight ... dogs, 63 percent say grilling is their favorite way to cook a hot dog, ...
(Date:5/26/2016)... , ... May 26, 2016 , ... ... discovery of thousands of defective respirators, according to court documents and SEC filings. ... of William and Becky Tyler v. American Optical Corporation, Case No. BC588866, Los ...
(Date:5/26/2016)... ... May 26, 2016 , ... Georgia State University ... specialty academic programs. , Answering to the increasing demand for curricular specializations, the ... law, and environmental and land use law. ,  , “The demand for lawyers ...
(Date:5/26/2016)... ... ... On Memorial Day, Hope For Heroes and USA Medical Card will ... country. The nonprofit Hope For Heroes partnered with the leading provider of free ... military veterans, as well as police, firemen, and EMS professionals across the country, and ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... , May 26, 2016 ... Associated With Both Cost Savings and Overall ... plc (LSE: BTG), an international specialist healthcare company, ... at the 21st Annual Meeting of ISPOR (International ... treatment of hepatocellular carcinoma (HCC) using yttrium-90 glass ...
(Date:5/25/2016)... 25,2016 FDA 510(k) clearance ... platform for urological and surgical applications ... of Cellvizio®, the multidisciplinary confocal laser endomicroscopy (CLE) ... the US with the 12 th 510(k) ... (FDA). This new FDA clearance covers Confocal Miniprobes ...
(Date:5/25/2016)... , Germany and GERMANTOWN, ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... licensing and co-development agreement with Therawis Diagnostics GmbH to develop ... be to develop and market PITX2 as a marker to ... high-risk breast cancer patients. "We are pleased to ...
Breaking Medicine Technology: