Navigation Links
Simple fingertip test may identify breast cancer patients at risk for carpal tunnel syndrome
Date:12/10/2010

A gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center scientists during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium.

SIMPLE FINGERTIP TEST MAY IDENTIFY BREAST CANCER PATIENTS AT RISK FOR CARPAL TUNNEL SYNDROME
(Presentation # P2-14-09)

As many as half of postmenopausal women taking aromatase inhibitor drugs for breast cancer complain of bothersome musculoskeletal symptoms, including carpal tunnel syndrome (CTS). Now, a new study by Johns Hopkins Kimmel Cancer Center researchers shows that a simple test that measures a woman's ability to feel two metal points pressed against her fingertips may help evaluate the risk for developing CTS.

CTS, most often associated with computer keyboard typing, is caused by bone growth in the wrist, compressing nerves and causing radiating arm pain and weak, numb hands and wrists.

For the study, researchers gathered and analyzed information on 104 women participating in a clinical trial of aromatase inhibitors exemestane and letrozole between September 2008 and June 2009. They recorded symptoms of pain and numbness common to carpal tunnel syndrome and also used a disc-criminator, a metal instrument with two sliding prongs used to measure tactile sensitivity. The instrument recorded the shortest distance between the prongs where the women could feel two pressure points versus one, called a two-point discrimination score. The tests were repeated three and six months later.

The percentage of women with carpal tunnel syndrome increased from 11 percent at baseline to 16 percent within six months of aromatase inhibitor treatment. The average two-point discrimination scores worsened from 3.4 mm to 4 mm within three months, particularly among overweight women.

"Our results show that the two-point discrimination score worsens in some women receiving aromatase inhibitor therapy, providing a potential way to measure risk for carpal tunnel syndrome," says lead author Aditya Bardia, M.D., M.P.H., a clinical fellow at the Johns Hopkins Kimmel Cancer Center

Larger studies are needed to confirm the findings before they can be incorporated into clinical practice, he adds.

If further studies confirm the findings, patients at risk for carpal tunnel syndrome could be referred to a rheumatologist for therapy during early stages of the syndrome before surgery is necessary, or could have their medication regimen switched, says senior author Vered Stearns, M.D., associate professor and co-director of the Breast Cancer Program at Johns Hopkins.


'/>"/>

Contact: Vanessa Wasta
wasta@jhmi.edu
410-614-2916
Johns Hopkins Medical Institutions
Source:Eurekalert

Related medicine news :

1. Simple Travel Tips Can Help Keep Pets Safe
2. Simple tools help parents understand a childs risk of obesity, make positive changes
3. Simpler and cheaper antibiotic prophylaxis with insertion of nutrition catheter in the stomach
4. Simple eye test measures damage from multiple sclerosis, UT Southwestern researchers find
5. Autism finding could lead to simple urine test for the condition
6. PC Encryption Compliance Delivered Through The Cloud Now Available As Simple Monthly Service For Business
7. Simple change results in fewer unnecessary imaging exams for patients
8. New research shows cardiologists can quickly detect significant coronary artery disease using a non-invasive simple, short respiratory stress test
9. New Implanted Defibrillator May Be Simpler, Safer
10. Simple Test May Identify Breast Cancer Subtypes
11. New "howsthepatient" iPhone App Provides a Simple, Seamless Way to Send Health Updates to Friends and Family
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... ... May 23, 2017 , ... MDLand ... Integration company, announced today that its iClinic V12.2 solution has achieved approval from ... NCQA recently introduced PCMH 2017 standards which emphasize team-based care with a significant ...
(Date:5/23/2017)... ... May 23, 2017 , ... New England Journal Of ... Worthy of a Policy Response”, -The Rory Staunton Foundation Calls on Health & Human ... the Prevention of Sepsis ( http://www.rorystauntonfoundation.org ) today reported on a new study released ...
(Date:5/23/2017)... ... , ... By all indications, and due to months of wet weather, there ... asking homeowners to scout for any open water sources that can be emptied or ... of mosquitos is the buzz associated with potential infections stemming from their itchy bites, ...
(Date:5/23/2017)... MA (PRWEB) , ... May 23, 2017 , ... Orbita’s ... on Tuesday, May 23, 2017 in San Francisco. Titled Connected Health and IoT: ... Connected Home Event hosted by Parks Associates, a market research and consulting firm ...
(Date:5/22/2017)... ... May 22, 2017 , ... The American Academy of ... healthcare training and clinical application of medical infrared imaging, has announced two new ... thermal imaging services. , The first new educational offering is an online self-directed ...
Breaking Medicine News(10 mins):
(Date:5/3/2017)... 2017  Getinge, a leading global provider of ... and cost efficiency within healthcare and life sciences, ... practice demonstrating that intra-aortic balloon counterpulsation (IABC) appears ... patients. The single-center, retrospective, observational study showed that ... ® 50cc intra-aortic balloon (IAB) in contemporary ...
(Date:5/2/2017)... and LONDON , May ... market intelligence, MarketResearch.com is pleased to announce a business ... that allows for the marketing and distribution of ... through the MarketResearch.com website. The new relationship ... complete product descriptions and tables of contents from research ...
(Date:5/2/2017)... Iowa , May 2, 2017  CIVCO ... patient-centric radiotherapy solutions, announced today that Nat ... been with CIVCO since 2012 and has served ... management, senior vice president and general manager, and ... "I am extremely proud of what ...
Breaking Medicine Technology: